Details
Stereochemistry | ACHIRAL |
Molecular Formula | H3N |
Molecular Weight | 16.0296 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[13NH3]
InChI
InChIKey=QGZKDVFQNNGYKY-BJUDXGSMSA-N
InChI=1S/H3N/h1H3/i1-1
Molecular Formula | H3N |
Molecular Weight | 16.0296 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
[13N]Ammonia ([13N]NH3) is a useful 13N-labeled compound that has been developed as a positron emission tomography (PET) imaging agent for assessing regional blood flow in tissues. It is indicated for diagnostic PET imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease. No adverse reactions have been reported for Ammonia N 13 Injection based on a review of the published literature, publicly available reference sources, and adverse drug reaction reporting systems. The possibility of interactions of Ammonia N 13 Injection with other drugs taken by patients undergoing PET imaging has not been studied.
Approval Year
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Diagnostic | AMMONIA N 13 Approved UseAmmonia N 13 Injection is a radioactive diagnostic agent for Positron Emission Tomography (PET) indicated for diagnostic PET imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease. Launch Date2007 |
Sample Use Guides
Rest Imaging Study:
• Aseptically withdraw Ammonia N 13 Injection from its container and administer 10-20 mCi (0.368 – 0.736 GBq) as a bolus through a catheter inserted into a large peripheral vein.
• Start imaging 3 minutes after the injection and acquire images for a total
of 10-20 minutes.
Stress Imaging Study:
• If a rest imaging study is performed, begin the stress imaging study 40 minutes or more after the first Ammonia N13 injection to allow sufficient isotope decay.
• Administer a pharmacologic stress-inducing drug in accordance with its
labeling.
• Aseptically withdraw Ammonia N 13 Injection from its container and
administer 10-20 mCi (0.368 – 0.736 GBq) of Ammonia N 13 Injection as a bolus at 8 minutes after the administration of the pharmacologic stress-inducing drug.
• Start imaging 3 minutes after the Ammonia N 13 Injection and acquire
images for a total of 10-20 minutes.
Route of Administration:
Intravenous
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 17:19:55 GMT 2023
by
admin
on
Fri Dec 15 17:19:55 GMT 2023
|
Record UNII |
9OQO0E343Z
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
NDF-RT |
N0000177914
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
||
|
NDF-RT |
N0000000205
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
||
|
NCI_THESAURUS |
C1446
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
DB09326
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
9OQO0E343Z
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
C79714
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
SUB11705MIG
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
1305558
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | RxNorm | ||
|
4472
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
9OQO0E343Z
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
135980
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
BB-73
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
34819-78-8
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
Ammonia N-13
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
CHEMBL1160819
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
Nitrogen-13
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
Ammonia N 13
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
DTXSID601027603
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY | |||
|
119432
Created by
admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
|
PRIMARY |
Related Record | Type | Details | ||
---|---|---|---|---|
|
NON-LABELED -> LABELED |
|
Related Record | Type | Details | ||
---|---|---|---|---|
|
ACTIVE MOIETY |
|