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Details

Stereochemistry ACHIRAL
Molecular Formula 3C14H9F3NO2.Al
Molecular Weight 867.649
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALUMINUM FLUFENAMATE

SMILES

c1ccc(c(c1)C(=O)[O-])Nc2cccc(c2)C(F)(F)F.c1ccc(c(c1)C(=O)[O-])Nc2cccc(c2)C(F)(F)F.c1ccc(c(c1)C(=O)[O-])Nc2cccc(c2)C(F)(F)F.[Al+3]

InChI

InChIKey=OSQHGAXCVAYZPZ-UHFFFAOYSA-K
InChI=1S/3C14H10F3NO2.Al/c3*15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20;/h3*1-8,18H,(H,19,20);/q;;;+3/p-3

HIDE SMILES / InChI

Molecular Formula C14H9F3NO2
Molecular Weight 280.2225
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Al
Molecular Weight 26.9815
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Aluminum flufenamate is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. Antiphlogistic pain reliever Opyrin (Aluminum flufenamate) was launched in Japan by Taisho Pharmaceutical in 1967.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Opyrin

Approved Use

Rheumatoid arthritis, osteoarthritis

Launch Date

-94694400000
Primary
Opyrin

Approved Use

Rheumatoid arthritis, osteoarthritis

Launch Date

-94694400000
PubMed

PubMed

TitleDatePubMed
Clinical evaluation of naproxen in the treatment of osteoarthritis--double-blind, cross-over trial.
1973
[Comparative effectiveness of new antirheumatic drugs].
1980
The bioavailability of flufenamic acid from aluminum flufenamate tablet and flufenamic acid capsule, and the influence of food and aluminum hydroxide gel.
1982 Mar
Patents

Sample Use Guides

Patients with osteoarthritis received aluminium flufenamate in a daily
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Jun 26 06:23:28 UTC 2021
Edited
by admin
on Sat Jun 26 06:23:28 UTC 2021
Record UNII
9NZ7H8YAHG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALUMINUM FLUFENAMATE
JAN  
Common Name English
ALUMINIUM FLUFENAMATE
Common Name English
ALUMINIUM N-(3'-TRIFLUOROMETHYLPHENY)ANTHRANILATE
Common Name English
ALUMINUM, TRIS(2-((3-(TRIFLUOROMETHYL)PHENYL)AMINO-.KAPPA.N)BENZOATO-.KAPPA.O)-
Common Name English
FLUFENAMATE ALUMINIUM [WHO-DD]
Common Name English
BENZOIC ACID, 2-((3-(TRIFLUOROMETHYL)PHENYL)AMINO)-, ALUMINUM SALT(3:1)
Common Name English
BENZOIC ACID, 2-((3-(TRIFLUOROMETHYL)PHENYL)AMINO)-, ALUMINIUM SALT(3:1)
Common Name English
ALUMINUM N-(3'-TRIFLUOROMETHYLPHENY)ANTHRANILATE
Common Name English
FLUFENAMATE ALUMINUM [JAN]
Common Name English
FLUFENAMATE ALUMINIUM
WHO-DD  
Common Name English
ALUMINIUM, TRIS(2-((3-(TRIFLUOROMETHYL)PHENYL)AMINO-.KAPPA.N)BENZOATO-.KAPPA.O)-
Common Name English
ALFENAMIN
Brand Name English
FLUFENAMIC ACID ALUMINUM SALT [MI]
Common Name English
OPYRIN
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C257
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
Code System Code Type Description
EPA CompTox
16449-54-0
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
PRIMARY
CAS
16449-54-0
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
PRIMARY
RXCUI
17612
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
PRIMARY RxNorm
NCI_THESAURUS
C79784
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
PRIMARY
MERCK INDEX
M5433
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
PRIMARY Merck Index
FDA UNII
9NZ7H8YAHG
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
PRIMARY
CAS
61891-34-7
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
ALTERNATIVE
MESH
C027885
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
PRIMARY
EVMPD
SUB02210MIG
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
PRIMARY
ECHA (EC/EINECS)
240-498-9
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
PRIMARY
PUBCHEM
27881
Created by admin on Sat Jun 26 06:23:28 UTC 2021 , Edited by admin on Sat Jun 26 06:23:28 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE