Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na]
InChI
InChIKey=MPMYQQHEHYDOCL-UHFFFAOYSA-N
InChI=1S/Na.H
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effect of increased dietary calcium on the development of reduced renal mass saline hypertension in rats. | 1990 Feb |
|
| Mechanisms of sodium retention in heart failure: relation to the renin-angiotensin-aldosterone system. | 1991 Jun |
|
| The role of cell swelling in the stimulation of glycogen synthesis by insulin. | 1992 Mar 15 |
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| Ni2+ transport by the human Na+/Ca2+ exchanger expressed in Sf9 cells. | 1999 May |
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| Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization. | 1999 May 21 |
|
| Molecular mechanism of the intestinal biotin transport process. | 1999 Oct |
|
| Influence of ammonia on sodium absorption in rat proximal colon. | 2000 Aug |
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| Inactivation properties of human recombinant class E calcium channels. | 2000 Feb |
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| Interactions of the renin-angiotensin system and neuronal nitric oxide synthase in regulation of cyclooxygenase-2 in the macula densa. | 2000 Jan |
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| Role of Na(+)/H(+) exchanger NHE3 in nephron function: micropuncture studies with S3226, an inhibitor of NHE3. | 2000 Mar |
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| The molecular basis for Na-dependent phosphate transport in human erythrocytes and K562 cells. | 2000 Sep |
|
| Alternatively spliced isoform of apical Na(+)-K(+)-Cl(-) cotransporter gene encodes a furosemide-sensitive Na(+)-Cl(-)cotransporter. | 2001 Apr |
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| Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi network. | 2001 May 18 |
|
| Role of superoxide in modulating the renal effects of angiotensin II. | 2003 Dec |
|
| Involvement of transient receptor potential-like channels in responses to mGluR-I activation in midbrain dopamine neurons. | 2003 Oct |
|
| The effect of cations on the amidase activity of human tissue kallikrein: 1-linear competitive inhibition by sodium, potassium, calcium and magnesium. 2-linear mixed inhibition by aluminium. | 2004 Aug |
|
| Glucocorticoid-mediated mineralocorticoid receptor activation and hypertension. | 2004 Jul |
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| The human tumour suppressor gene SLC5A8 expresses a Na+-monocarboxylate cotransporter. | 2004 Jun 15 |
|
| Biotin uptake by human proximal tubular epithelial cells: cellular and molecular aspects. | 2005 Apr |
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| Na+/Ca2+ exchanger activity modulates connective tissue growth factor mRNA expression in transforming growth factor beta1- and Des-Arg10-kallidin-stimulated myofibroblasts. | 2005 Apr 15 |
|
| Monovalent cation leaks in human red cells caused by single amino-acid substitutions in the transport domain of the band 3 chloride-bicarbonate exchanger, AE1. | 2005 Nov |
|
| High-yield functional expression of human sodium/d-glucose cotransporter1 in Pichia pastoris and characterization of ligand-induced conformational changes as studied by tryptophan fluorescence. | 2005 Nov 29 |
|
| The mineralocorticoid receptor: a journey exploring its diversity and specificity of action. | 2005 Sep |
|
| Triphenyltin impairs a protein kinase A (PKA)-dependent increase of cytosolic Na+ and Ca2+ and PKA-independent increase of cytosolic Ca2+ associated with insulin secretion in hamster pancreatic beta-cells. | 2006 Nov 1 |
|
| Adaptive downregulation of a quinidine-sensitive cation conductance in renal principal cells of TWIK-1 knockout mice. | 2006 Oct |
|
| Evidence for a decrease in cardiovascular risk factors following recombinant growth hormone administration in abstinent anabolic-androgenic steroid users. | 2007 Jun |
|
| Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha-hydroxylase expression in vitro. | 2007 Nov |
|
| G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis. | 2008 Sep |
|
| A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia. | 2009 Aug 18 |
|
| Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation. | 2009 Jan |
|
| Human and rat Nav1.3 voltage-gated sodium channels differ in inactivation properties and sensitivity to the pyrethroid insecticide tefluthrin. | 2009 Jan |
|
| Effects of enalapril and sodium depletion on the renin-angiotensin system in hydronephrotic mice. | 2009 Jul |
|
| Interaction of sodium loading and enalapril on renin mRNA and renin release in hydronephrotic mice. | 2009 Jun 25 |
|
| Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770. | 2009 Nov 3 |
|
| Long-term terbutaline exposure stimulates alpha1-Na+-K+-ATPase expression at posttranscriptional level in rat fetal distal lung epithelial cells. | 2010 Jan |
|
| Low temperature and chemical rescue affect molecular proximity of DeltaF508-cystic fibrosis transmembrane conductance regulator (CFTR) and epithelial sodium channel (ENaC). | 2012 May 11 |
|
| Increased zinc and manganese in parallel with neurodegeneration, synaptic protein changes and activation of Akt/GSK3 signaling in ovine CLN6 neuronal ceroid lipofuscinosis. | 2013 |
|
| Varicella-zoster viruses associated with post-herpetic neuralgia induce sodium current density increases in the ND7-23 Nav-1.8 neuroblastoma cell line. | 2013 |
|
| Nickel induces interleukin-1β secretion via the NLRP3-ASC-caspase-1 pathway. | 2014 Apr |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:53:41 GMT 2023
by
admin
on
Fri Dec 15 15:53:41 GMT 2023
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| Record UNII |
9NEZ333N27
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| Record Status |
Validated (UNII)
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| Record Version |
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| Classification Tree | Code System | Code | ||
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CFR |
21 CFR 176.170
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DSLD |
145 (Number of products:10421)
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FDA ORPHAN DRUG |
408413
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CFR |
21 CFR 101.74
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26763-3
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CFR |
21 CFR 862.1665
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| Code System | Code | Type | Description | ||
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C830
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231-132-9
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100000078099
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5360545
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9NEZ333N27
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Sodium
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m9978
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687
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| Related Record | Type | Details | ||
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PARENT -> CONSTITUENT ALWAYS PRESENT |
Nutritional value per 100 g (3.5 oz) - 33 mg (2%)
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