CLOMETOCILLIN SODIUM

Details

Stereochemistry	EPIMERIC
Molecular Formula	C17H17Cl2N2O5S.Na
Molecular Weight	455.288
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C(OC)C3=CC=C(Cl)C(Cl)=C3)C([O-])=O

InChI

InChIKey=VJOSJOPYZRNYSD-HUDLNOPTSA-M

InChI=1S/C17H18Cl2N2O5S.Na/c1-17(2)12(16(24)25)21-14(23)10(15(21)27-17)20-13(22)11(26-3)7-4-5-8(18)9(19)6-7;/h4-6,10-12,15H,1-3H3,(H,20,22)(H,24,25);/q;+1/p-1/t10-,11?,12+,15-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C17H17Cl2N2O5S
Molecular Weight	432.298
Charge	-1
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	3 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14145726 | https://www.ncbi.nlm.nih.gov/pubmed/9578165

Clometocillin, one of the forms of penicillin, was active against pen-I or pen-R pneumococci and was used in children. The modern information about its application is not available.

Approval Year

PubMed

Title	Date	PubMed
[USE IN CHILDREN OF A NEW ORAL PENICILLIN: CLOMETOCILLIN].	1964 Apr 25	14145726
In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae.	1998 Mar	9578165

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:51:38 GMT 2023` Edited by `admin` on `Sat Dec 16 08:51:38 GMT 2023`
Record UNII	9N5QS4F3AF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLOMETOCILLIN SODIUM

Common Name

English

CLOMETOCILLIN SODIUM SALT [MI]

Common Name

English

CLOMETOCILLIN SODIUM SALT

Common Name

English

RIXAPEN

Common Name

English

4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, 6-(((3,4-DICHLOROPHENYL)METHOXYACETYL)AMINO)-3,3-DIMETHYL-7-OXO-, MONOSODIUM SALT, (2S-(2.ALPHA.,5.ALPHA.,6.BETA.))-

Systematic Name

English

Code System Code Type Description

MERCK INDEX

m3646