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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 11:33:21 GMT 2025
Edited
by admin
on Wed Apr 02 11:33:21 GMT 2025
Protein Type ENZYME
Protein Sub Type PHOSPHATASE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
9N4Y2R43OM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RECAP
Preferred Name English
ILOFOTASE ALFA
USAN   INN  
Official Name English
ilofotase alfa [INN]
Common Name English
ILOFOTASE ALFA [USAN]
Common Name English
HUMAN RECAP
Common Name English
-365-INTESTINAL ALKALINE PHOSPHATASE (279-LEUCINE,328-VALINE) (HUMAN) FUSION PROTEIN WITH 366-430-PLACENTAL ALKALINE PHOSPHATASE (HUMAN) FUSION PROTEIN WITH 431-484-INTESTINAL ALKALINE PHOSPHATASE (478-LEUCINE) (HUMAN), DIMER
Common Name English
RECOMBINANT HUMAN ALKALINE PHOSPHATASE (HUMAN INTESTINAL (ALPI), PLACENTAL (ALPP) CHIMERIC PROTEIN)
Common Name English
HUMAN INTESTINAL-TYPE ALKALINE PHOSPHATASE (IAP) VARIANT (H279>L, L328>V, P478>L), ENGINEERED BY SUBSTITUTING ITS CROWN DOMAIN (366-430) WITH THE HUMAN PLACENTAL-TYPE ALKALINE PHOSPHATASE (PLACENTAL ALKALINE PHOSPHATASE 1, PLAP-1) CROWN DOMAIN (364-428,
Common Name English
CHIMERIC HUMAN ALKALINE PHOSPHATASE (HUMAN INTESTINAL ALKALINE PHOSPHATASE (HIAP) CATALYTIC DOMAIN AND THE HUMAN PLACENTAL ALKALINE PHOSPHATASE (HPLAP) CROWN DOMAIN THAT LACKS THE GLYCOSYLPHOSPHATIDYLINOSITOL (GPI) ANCHOR OF HIAP)
Common Name English
Code System Code Type Description
INN
11641
Created by admin on Wed Apr 02 11:33:21 GMT 2025 , Edited by admin on Wed Apr 02 11:33:21 GMT 2025
PRIMARY INN
NCI_THESAURUS
C179090
Created by admin on Wed Apr 02 11:33:21 GMT 2025 , Edited by admin on Wed Apr 02 11:33:21 GMT 2025
PRIMARY
USAN
JK-253
Created by admin on Wed Apr 02 11:33:21 GMT 2025 , Edited by admin on Wed Apr 02 11:33:21 GMT 2025
PRIMARY
CAS
2387636-92-0
Created by admin on Wed Apr 02 11:33:21 GMT 2025 , Edited by admin on Wed Apr 02 11:33:21 GMT 2025
PRIMARY
SMS_ID
100000169924
Created by admin on Wed Apr 02 11:33:21 GMT 2025 , Edited by admin on Wed Apr 02 11:33:21 GMT 2025
PRIMARY
FDA UNII
9N4Y2R43OM
Created by admin on Wed Apr 02 11:33:21 GMT 2025 , Edited by admin on Wed Apr 02 11:33:21 GMT 2025
PRIMARY
From To
1_101 2_101
1_121 1_183
1_481 2_481
1_467 1_474
2_121 2_183
2_467 2_474
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_122
N 1_249
N 2_122
N 2_249
Related Record Type Details
Structure of ADENOSINE TRIPHOSPHATE
TARGET -> SUBSTRATE
recAP has a dual mechanism of action via dephosphorylation of both lipopolysaccharides (LPS) and extracellular ATP.
Related Record Type Details
ILOFOTASE ALFA
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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