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Details

Stereochemistry ACHIRAL
Molecular Formula C21H24I3NO4.ClH
Molecular Weight 771.594
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of THYROMEDAN HYDROCHLORIDE

SMILES

Cl.CCN(CC)CCOC(=O)CC1=CC(I)=C(OC2=CC=C(OC)C(I)=C2)C(I)=C1

InChI

InChIKey=MNIDQQFSKKUQGQ-UHFFFAOYSA-N
InChI=1S/C21H24I3NO4.ClH/c1-4-25(5-2)8-9-28-20(26)12-14-10-17(23)21(18(24)11-14)29-15-6-7-19(27-3)16(22)13-15;/h6-7,10-11,13H,4-5,8-9,12H2,1-3H3;1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C21H24I3NO4
Molecular Weight 735.133
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Thyromedan is a thyroalkanoic acid derivative with hypocholesterolemic activity. In clinical trials, Thyromedan in daily doses of 8 to 32 mg caused a decrease in serum cholesterol levels. The serum total triglycerides and the α- and β-lipoprotein partition of cholesterol and triglycerides were unaffected.

Originator

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Patents

Patents

20060024365
8

Sample Use Guides

In Vivo Use Guide
8 to 32 mg/day
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:16:56 GMT 2023
Edited
by admin
on Fri Dec 15 15:16:56 GMT 2023
Record UNII
9L1802A75R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
THYROMEDAN HYDROCHLORIDE
USAN  
USAN  
Official Name English
TYROMEDAN HYDROCHLORIDE
Common Name English
2-(Diethylamino)ethyl [3,5-diiodo-4-(3-iodo-4-methoxyphenoxy)phenyl]acetate hydrochloride
Systematic Name English
BENZENEACETIC ACID, 3,5-DIIODO-4-(3-IODO-4-METHOXYPHENOXY)-, 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE
Common Name English
SK&F-13364-A
Code English
THYROMEDAN HYDROCHLORIDE [USAN]
Common Name English
THYROMEDAN HCL
Common Name English
SK&F 13364-A
Code English
Classification Tree Code System Code
NCI_THESAURUS C1553
Created by admin on Fri Dec 15 15:16:56 GMT 2023 , Edited by admin on Fri Dec 15 15:16:56 GMT 2023
Code System Code Type Description
FDA UNII
9L1802A75R
Created by admin on Fri Dec 15 15:16:56 GMT 2023 , Edited by admin on Fri Dec 15 15:16:56 GMT 2023
PRIMARY
EPA CompTox
DTXSID10205605
Created by admin on Fri Dec 15 15:16:56 GMT 2023 , Edited by admin on Fri Dec 15 15:16:56 GMT 2023
PRIMARY
ChEMBL
CHEMBL2111061
Created by admin on Fri Dec 15 15:16:56 GMT 2023 , Edited by admin on Fri Dec 15 15:16:56 GMT 2023
PRIMARY
NCI_THESAURUS
C80845
Created by admin on Fri Dec 15 15:16:56 GMT 2023 , Edited by admin on Fri Dec 15 15:16:56 GMT 2023
PRIMARY
CAS
57-65-8
Created by admin on Fri Dec 15 15:16:56 GMT 2023 , Edited by admin on Fri Dec 15 15:16:56 GMT 2023
PRIMARY
PUBCHEM
151112
Created by admin on Fri Dec 15 15:16:56 GMT 2023 , Edited by admin on Fri Dec 15 15:16:56 GMT 2023
PRIMARY
NIH
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