SR-144190 HYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C33H38F2N4O3.ClH
Molecular Weight	613.138
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CN(C)C(=O)NC1(CCN(CC[C@]2(CN(CCO2)C(=O)C3=CC=CC=C3)C4=CC(F)=C(F)C=C4)CC1)C5=CC=CC=C5

InChI

InChIKey=CUYCXSCEWNTJEZ-WAQYZQTGSA-N

InChI=1S/C33H38F2N4O3.ClH/c1-37(2)31(41)36-32(26-11-7-4-8-12-26)15-18-38(19-16-32)20-17-33(27-13-14-28(34)29(35)23-27)24-39(21-22-42-33)30(40)25-9-5-3-6-10-25;/h3-14,23H,15-22,24H2,1-2H3,(H,36,41);1H/t33-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	C33H38F2N4O3
Molecular Weight	576.6766
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Biochemical and pharmacological activities of SR 144190, a new potent non-peptide tachykinin NK2 receptor antagonist.	1997 Oct	9413022
Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays.	2013 Jun 17	23611293

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 19:11:31 GMT 2023` Edited by `admin` on `Sat Dec 16 19:11:31 GMT 2023`
Record UNII	9K6Z7W9CH3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SR-144190 HYDROCHLORIDE

Common Name

English

MORPHOLINE, 4-BENZOYL-2-(3,4-DIFLUOROPHENYL)-2-(2-(4-(((DIMETHYLAMINO)CARBONYL)AMINO)-4-PHENYL-1-PIPERIDINYL)ETHYL)-, MONOHYDROCHLORIDE, (2R)-

Systematic Name

English

UREA, N'-(1-(2-((2R)-4-BENZOYL-2-(3,4-DIFLUOROPHENYL)-2-MORPHOLINYL)ETHYL)-4-PHENYL-4-PIPERIDINYL)-N,N-DIMETHYL-, HYDROCHLORIDE (1:1)

Systematic Name

English

3-(1-(2-((2R)-4-BENZOYL-2-(3,4-DIFLUOROPHENYL)MORPHOLIN-2-YL)ETHYL)-4-PHENYLPIPERIDIN-4-YL)-1,1-DIMETHYLUREA HYDROCHLORIDE (1:1)

Systematic Name

English

Code System Code Type Description

FDA UNII

9K6Z7W9CH3

Created by admin on Sat Dec 16 19:11:31 GMT 2023 , Edited by admin on Sat Dec 16 19:11:31 GMT 2023

PRIMARY

PUBCHEM

60196402

Created by admin on Sat Dec 16 19:11:31 GMT 2023 , Edited by admin on Sat Dec 16 19:11:31 GMT 2023

PRIMARY

EPA CompTox

DTXSID4047339

Created by admin on Sat Dec 16 19:11:31 GMT 2023 , Edited by admin on Sat Dec 16 19:11:31 GMT 2023

PRIMARY

CAS

181640-09-5

Created by admin on Sat Dec 16 19:11:31 GMT 2023 , Edited by admin on Sat Dec 16 19:11:31 GMT 2023

PRIMARY

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