LMV-601

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NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C11H15OS2.K
Molecular Weight	266.465
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LMV-601

Structure Search

SMILES

[K+].[H][C@]12CCC[C@@]1([H])[C@H]3C[C@@H]2C[C@@H]3OC([S-])=S

InChI

InChIKey=IGULCCCBGBDZKQ-UATZLORTSA-M

InChI=1S/C11H16OS2.K/c13-11(14)12-10-5-6-4-9(10)8-3-1-2-7(6)8;/h6-10H,1-5H2,(H,13,14);/q;+1/p-1/t6-,7-,8-,9-,10+;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C11H15OS2
Molecular Weight	227.366
Charge	-1
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	K
Molecular Weight	39.0983
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Phosphatidylcholine-specific phospholipase C 2 Target ID: Phosphatidylcholine-specific phospholipase C Sources: http://www.lesgaga.com/pipeline.html\|https://www.ncbi.nlm.nih.gov/pubmed/21046515	Inhibitor 8297
Protein kinase C (PKC) 44 Target ID: CHEMBL2093867 Sources: http://www.lesgaga.com/pipeline.html	Inhibitor 8297

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:12:12 GMT 2023` Edited by `admin` on `Sat Dec 16 05:12:12 GMT 2023`
Record UNII	9K6IDM1E83
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LMV-601

Common Name

English

SPK-601

Code

English

CARBONODITHIOIC ACID, O-((3AR,4R,5S,7R,7AR)-OCTAHYDRO-4,7-METHANO-1H-INDEN-5-YL) ESTER, POTASSIUM SALT (1:1)

Systematic Name

English

LMV-601 [MI]

Common Name

English

D609, C-EXO-O-EXO-(S)-

Code

English

D609, C-EXO-O-EXO-(-)-

Code

English

Code System Code Type Description

EPA CompTox

DTXSID60735361

Created by admin on Sat Dec 16 05:12:12 GMT 2023 , Edited by admin on Sat Dec 16 05:12:12 GMT 2023

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PUBCHEM

46909535

Created by admin on Sat Dec 16 05:12:12 GMT 2023 , Edited by admin on Sat Dec 16 05:12:12 GMT 2023

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FDA UNII

9K6IDM1E83

Created by admin on Sat Dec 16 05:12:12 GMT 2023 , Edited by admin on Sat Dec 16 05:12:12 GMT 2023

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CAS

1096687-52-3

Created by admin on Sat Dec 16 05:12:12 GMT 2023 , Edited by admin on Sat Dec 16 05:12:12 GMT 2023

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MANUFACTURER PRODUCT INFORMATION

LMV-601

Created by admin on Sat Dec 16 05:12:12 GMT 2023 , Edited by admin on Sat Dec 16 05:12:12 GMT 2023

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Biological Activity of SPK-601: SPK-601(LMV-601) is a potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor., SPK-601 is useful antimicrobial agent. Target: PC-PLC

MERCK INDEX

m11847

Created by admin on Sat Dec 16 05:12:12 GMT 2023 , Edited by admin on Sat Dec 16 05:12:12 GMT 2023

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Related Record Type Details


					9K6IDM1E83

LMV-601

ACTIVE MOIETY

Comments:

Originator: BioSphings; Developer: Lumavita; Class: Antiviral, Small molecule; Mechanism of Action: Phosphatidylcholine-specific phospholipase C inhbitor; Highest Development Phase: Phase I for Herpes simplex virus infections, Human papillomavirus infections; Most Recent Events: 15 Mar 2011 Phase-I clinical trials in Human papillomavirus infections in Germany (Topical), 02 Feb 2006 Preclinical trials in Human papillomavirus infections in Japan (unspecified route), 02 Feb 2006 Preclinical trials in Herpes zoster in Japan (unspecified route)