U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Details

Stereochemistry RACEMIC
Molecular Formula C23H17FN6O2
Molecular Weight 428.4185
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CMN-290

SMILES

CNC(=O)C1=CC=C(C=C1F)C2=NN3C(=CN=C3N=C2)C(O)C4=CC5=CC=CN=C5C=C4

InChI

InChIKey=OQRVHBURGPDXFS-UHFFFAOYSA-N
InChI=1S/C23H17FN6O2/c1-25-22(32)16-6-4-14(10-17(16)24)19-11-27-23-28-12-20(30(23)29-19)21(31)15-5-7-18-13(9-15)3-2-8-26-18/h2-12,21,31H,1H3,(H,25,32)

HIDE SMILES / InChI

Molecular Formula C23H17FN6O2
Molecular Weight 428.4185
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

Substance Class Chemical
Created
by admin
on Wed Apr 02 07:50:19 GMT 2025
Edited
by admin
on Wed Apr 02 07:50:19 GMT 2025
Record UNII
9K3JG6H3K5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CMN290
Preferred Name English
CMN-290
Code English
2-FLUORO-4-(7-(HYDROXY(6-QUINOLYL)METHYL)IMIDAZO(1,2-B)(1,2,4)TRIAZIN-2-YL)-N-METHYL-BENZAMIDE
Systematic Name English
CAPMATINIB METABOLITE M8
Common Name English
Code System Code Type Description
FDA UNII
9K3JG6H3K5
Created by admin on Wed Apr 02 07:50:19 GMT 2025 , Edited by admin on Wed Apr 02 07:50:19 GMT 2025
PRIMARY
PUBCHEM
165412044
Created by admin on Wed Apr 02 07:50:19 GMT 2025 , Edited by admin on Wed Apr 02 07:50:19 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> METABOLITE
PLASMA
PARENT -> METABOLITE
MINOR
FECAL; URINE