IOLOPRIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C15H21IN2O3
Molecular Weight	404.2433
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN1CCC[C@H]1CNC(=O)C2=C(O)C(I)=CC=C2OC

InChI

InChIKey=CANPFCFJURGKAX-JTQLQIEISA-N

InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C15H21IN2O3
Molecular Weight	404.2433
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Vulnerability of positron emission tomography radiotracers to endogenous competition. New insights.	2001 Jun	11476162
The variable number of tandem repeats polymorphism of the dopamine transporter gene is not associated with significant change in dopamine transporter phenotype in humans.	2001 May	11282255
Dopamine D(2) receptor availability and amphetamine-induced dopamine release in unipolar depression.	2001 Sep 1	11543733
Cerebrospinal fluid analysis differentiates multiple system atrophy from Parkinson's disease.	2004 May	15133823
Striatal amphetamine-induced dopamine release in patients with schizotypal personality disorder studied with single photon emission computed tomography and [123I]iodobenzamide.	2004 May 15	15121484
Abnormalities of dopaminergic neurotransmission in SCA2: a combined 123I-betaCIT and 123I-IBZM SPECT study.	2004 Nov	15390003
Occupancy of dopamine D2 receptors by the atypical antipsychotic drugs risperidone and olanzapine: theoretical implications.	2004 Oct	15083259
Combined 123I-FP-CIT and 123I-IBZM SPECT for the diagnosis of parkinsonian syndromes: study on 72 patients.	2005 May	15375677
Dopaminergic function in a family with the PARK6 form of autosomal recessive Parkinson's syndrome.	2005 Oct	15785866
Acute prefrontal rTMS increases striatal dopamine to a similar degree as D-amphetamine.	2007 Dec 15	17993266
Decreased dopamine transporter availability in male smokers -- a dual isotope SPECT study.	2008 Jan 1	17900774
Baseline and amphetamine-stimulated dopamine activity are related in drug-naïve schizophrenic subjects.	2009 Jun 15	19167701
Simultaneous 99mTc and 123I dual-isotope brain striatal phantom single photon emission computed tomography: validation of 99mTc-TRODAT-1 and 123I-IBZM simultaneous dopamine system brain imaging.	2009 Nov	19858039
Impact of scatter correction on D2 receptor occupancy measurements using 123I-IBZM SPECT: comparison to 11C-Raclopride PET.	2010 May 1	20083205

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:00:37 GMT 2023` Edited by `admin` on `Sat Dec 16 09:00:37 GMT 2023`
Record UNII	9J5D4ZN1JK
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IOLOPRIDE

Common Name

English

(S)-(-)-IBZM

Common Name

English

N-(((2S)-1-ETHYLPYRROLIDIN-2-YL)METHYL)-2-HYDROXY-3-IODO-6-METHOXYBENZAMIDE

Systematic Name

English

BENZAMIDE, N-(((2S)-1-ETHYL-2-PYRROLIDINYL)METHYL)-2-HYDROXY-3-IODO-6-METHOXY-

Systematic Name

English

(S)-N-(1-ETHYL-2-PYRROLIDINYL)METHYL-2-HYDROXY-3-IODO-6-METHOXYBENZAMIDE

Systematic Name

English

(S)-N-((1-ETHYLPYRROLIDIN-2-YL)METHYL)-2-HYDROXY-3-IODO-6-METHOXYBENZAMIDE

Systematic Name

English

N-(((2S)-1-ETHYL-2-PYRROLIDINYL)METHYL)-2-HYDROXY-3-IODO-6-METHOXYBENZAMIDE

Systematic Name

English

BENZAMIDE, N-((1-ETHYL-2-PYRROLIDINYL)METHYL)-2-HYDROXY-3-IODO-6-METHOXY-, (S)-

Systematic Name

English

(S)-(-)-3-IODO-2-HYDROXY-6-METHOXY-N-((1-ETHYL-2-PYRROLIDINYL)METHYL)BENZAMIDE

Systematic Name

English

Code System Code Type Description

CAS

84226-06-2