AMENTOFLAVONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C30H18O10
Molecular Weight	538.4579
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC=C(C=C1)C2=CC(=O)C3=C(O)C=C(O)C(C4=CC(=CC=C4O)C5=CC(=O)C6=C(O)C=C(O)C=C6O5)=C3O2

InChI

InChIKey=YUSWMAULDXZHPY-UHFFFAOYSA-N

InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H

HIDE SMILES / InChI

Molecular Formula	C30H18O10
Molecular Weight	538.4579
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Biflavonoids as novel antituberculosis agents.	2001 Aug 20	11514148
Antiviral amentoflavone from Selaginella sinensis.	2001 Mar	11256492
Downregulation of COX-2 and iNOS by amentoflavone and quercetin in A549 human lung adenocarcinoma cell line.	2002 May-Jun	12144868
Inhibition of TNFalpha-induced cyclooxygenase-2 expression by amentoflavone through suppression of NF-kappaB activation in A549 cells.	2002 Sep	12349896
Inhibition of COX isoforms by nutraceuticals.	2004	15364641
Cytotoxic effects of mammea type coumarins from Calophyllum brasiliense.	2004 Aug 13	15261767
Effects of St. John's wort extract and single constituents on stress-induced hyperthermia in mice.	2006 Dec	17051457
Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 1.	2006 Feb	17576437
[Determination of amentoflavone in 11 species of Selaginella medicinal material by HPLC].	2006 Jan	16722315
Inhibition of human cytochrome CYP 1 enzymes by flavonoids of St. John's wort.	2006 Jan 16	16271822
Amentoflavone, a biflavonoid from Biophytum sensitivum augments lymphocyte proliferation, natural killer cell and antibody dependent cellular cytotoxicity through enhanced production of IL-2 and IFN-gamma and restrains serum sialic acid and gamma glutamyl transpeptidase production in tumor - bearing animals.	2007	18038762
Phytochemical investigation and hepatoprotective activity of Cupressus sempervirens L. leaves growing in Egypt.	2007 Aug	17680494
Antimalarial and vasorelaxant constituents of the leaves of Allanblackia monticola (Guttiferae).	2007 Jan	17244407
In silico prediction of pregnane X receptor activators by machine learning approaches.	2007 Jan	17003167
[Study on HPLC fingerprint characteristics of Selaginella plants].	2007 Oct	18306737
Brain-to-plasma distribution ratio of the biflavone amentoflavone in the mouse.	2008 Apr	19356077
Inhibition of tumor specific angiogenesis by amentoflavone.	2008 Feb	18298378
Seco-terpenoids and other constituents from Elateriospermum tapos.	2008 Feb	18179177
Biflavonoids isolated from Selaginella tamariscina regulate the expression of matrix metalloproteinase in human skin fibroblasts.	2008 Jan 15	18029185
How to realize the linear scale-up process for rapid purification using high-performance counter-current chromatography.	2008 Jun 20	18479689
Modulatory effect of Byrsonima basiloba extracts on the mutagenicity of certain direct and indirect-acting mutagens in Salmonella typhimurium assays.	2008 Mar	18361746
Antimicrobial activity of the crude extracts and five flavonoids from the twigs of Dorstenia barteri (Moraceae).	2008 Mar 28	18280679
Anti-Helicobacter pylori activity and immunostimulatory effect of extracts from Byrsonima crassa Nied. (Malpighiaceae).	2009 Jan 16	19149866

Substance Class	Chemical Created by `admin` on `Fri Dec 15 20:09:53 GMT 2023` Edited by `admin` on `Fri Dec 15 20:09:53 GMT 2023`
Record UNII	9I1VC79L77
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AMENTOFLAVONE

Official Name

English

3''',8-BIFLAVONE, 4',4''',5,5'',7,7''-HEXAHYDROXY

Common Name

English

I3',II8-BIAPIGENIN

Common Name

English

GINKGETIN, DIDEMETHYL-

Common Name

English

AMENTOFLAVONE [INCI]

Common Name

English

TRIDEMETHYLSCIADOPITYSIN

Common Name

English

4H-1-BENZOPYRAN-4-ONE, 8-(5-(5,7-DIHYDROXY-4-OXO-4H-1-BENZOPYRAN-2-YL)-2-HYDROXYPHENYL)-5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)-

Systematic Name

English

NSC-295677

Code

English

AMENTHOFLAVONE

Common Name

English

Classification Tree Code System Code

DSLD

3991 (Number of products:2)