Ethyl methanesulfonate

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C3H8O3S
Molecular Weight	124.159
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOS(C)(=O)=O

InChI

InChIKey=PLUBXMRUUVWRLT-UHFFFAOYSA-N

InChI=1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C3H8O3S
Molecular Weight	124.159
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Induction of genome instability by DNA damage in Saccharomyces cerevisiae.	2003-03-01	12547388
Conserved residues R420 and Q428 in a cytoplasmic loop of the citrate/malate transporter CimH of Bacillus subtilis are accessible from the external face of the membrane.	2003-01-21	12525174
Ethylmethanesulfonate saturation mutagenesis in Arabidopsis to determine frequency of herbicide resistance.	2003-01	12529522
Repairability during G1 of lesions eliciting sister chromatid exchanges induced by methylmethanesulfonate or ethylmethanesulfonate in bromodeoxyuridine-substituted and unsubstituted DNA strands.	2003-01	12473730
Post-genomic insights into plant nodulation symbioses.	2003	12540294
Identification of cells deficient in signaling-induced alternative splicing by use of somatic cell genetics.	2002-12	12515380
Genetic analyses of essential genes in cytological region 61D1-2 to 61F1-2 of Drosophila melanogaster.	2002-12	12471442
Comparative surface accessibility of a pore-lining threonine residue (T6') in the glycine and GABA(A) receptors.	2002-11-22	12239220
Identification of a tyrosine in the agonist binding site of the homomeric rho1 gamma-aminobutyric acid (GABA) receptor that, when mutated, produces spontaneous opening.	2002-11-15	12226075
Serotonin 5-HT(3) receptors in rat CA1 hippocampal interneurons: functional and molecular characterization.	2002-11-01	12411518
Chemotherapeutically induced deletion of expanded triplet repeats.	2002-10-31	12379466
A ubiquitin-proteasome pathway represses the Drosophila immune deficiency signaling cascade.	2002-10-15	12401167
Accessibility and conformational coupling in serotonin transporter predicted internal domains.	2002-10-01	12351711
DNA alkylating agents alleviate silencing of class II transactivator gene expression in L1210 lymphoma cells.	2002-09-15	12218125
[Arabidopsis: a genetic tool to know the unknowns].	2002-09	12357596
Localization of the activation gate for small conductance Ca2+-activated K+ channels.	2002-08-01	12151529
Alteration in the cytosolic triacylglycerol biosynthetic machinery leads to decreased cell growth and triacylglycerol synthesis in oleaginous yeast.	2002-08-01	11972450
Monitoring DNA damage in wood small-reed (Calamagrostis epigejos) plants growing in a sediment reservoir with substrates from uranium mining.	2002-08	12196007
Screening for gene regulation mutants by bioluminescence imaging.	2002-07-09	12107339
Site-directed mutagenesis and chemical modification of the six native cysteine residues of the rat mitochondrial carnitine carrier: implications for the role of cysteine-136.	2002-07-09	12093282
Influence of mus201 and mus308 mutations of Drosophila melanogaster on the genotoxicity of model chemicals in somatic cells in vivo measured with the comet assay.	2002-06-19	12052499
Use of an in situ disulfide cross-linking strategy to map proximities between amino acid residues in transmembrane domains I and VII of the M3 muscarinic acetylcholine receptor.	2002-06-18	12056896
DNA methylation and epigenetic inheritance.	2002-06	12095278
Molecular and physiological analysis of Arabidopsis mutants defective in cytosolic or chloroplastic aspartate aminotransferase.	2002-06	12068109
The jing Zn-finger transcription factor is a mediator of cellular differentiation in the Drosophila CNS midline and trachea.	2002-06	12015288
[Clastogenicity of ethyl methanesulfonate and dimethyl terephthalate in the micronucleus test and ways for its modification].	2002-05-16	12012591
[Study on genetic radioresistance of natural Drosophila Melanogaster population from radionuclide contaminated regions of Byelarus].	2002-05-15	12004604
Harlequin (hlq) and short blue root (sbr), two Arabidopsis mutants that ectopically express an abscisic acid- and auxin-inducible transgenic carrot promoter and have pleiotropic effects on morphogenesis.	2002-05	12008902
[Analysis of brain morphological changes induced by ethyl methanesulfonate in Drosophila melanogaster].	2002-04-12	11944325
[Mutagens inducing mutations in mammalian mitochondrial DNA].	2002-04	12013884
Efficacy of vitamin-C (L-ascorbic acid) in reducing genotoxicity in fish (Oreochromis mossambicus) induced by ethyl methane sulphonate.	2002-04	11996135
Tomato mutants as tools for functional genomics.	2002-04	11856605
Cytoplasmic vestibule of the weak inward rectifier Kir6.2 potassium channel.	2002-03-22	11790775
The NMDA receptor M3 segment is a conserved transduction element coupling ligand binding to channel opening.	2002-03-15	11896144
DNA damage and repair in lymphoblastoid cell lines from normal donors and fragile X syndrome patients.	2002-03-12	11886710
Evidence for a centrally located gate in the pore of a serotonin-gated ion channel.	2002-03-01	11880493
Ethanol-enhanced cytotoxicity of alkylating agents.	2002-03	11923592
Induction of micronuclei in human cell lines and primary cells by combination treatment with gamma-radiation and ethyl methanesulfonate.	2002-03	11880548
Large-scale structure-function analysis of the Arabidopsis RPM1 disease resistance protein.	2002-02	11884685
Interallelic complementation provides genetic evidence for the multimeric organization of the Phycomyces blakesleeanus phytoene dehydrogenase.	2002-02	11846791
Mapping the agonist binding site of the nicotinic acetylcholine receptor by cysteine scanning mutagenesis: antagonist footprint and secondary structure prediction.	2002-02	11809872
Evaluation of genotoxic activity of maleic hydrazide, ethyl methane sulfonate, and N-nitroso diethylamine in Tradescantia.	2002-01-31	11816231
[Genoprotective human blood activity and its mechanisms].	2002-01	11868261
Root, root hair, and symbiotic mutants of the model legume Lotus japonicus.	2002-01	11843301
Yeast nuclear genes for mtDNA maintenance.	2002	12013792
Influence of sodium arsenite on the genotoxicity of potassium dichromate and ethyl methanesulfonate: studies with the wing spot test in Drosophila.	2002	11813296
The mitochondrial oxoglutarate carrier: cysteine-scanning mutagenesis of transmembrane domain IV and sensitivity of Cys mutants to sulfhydryl reagents.	2001-12-25	11747458
A gap junctionally transmitted epithelial cell signal regulates endocytic yolk uptake in Oncopeltus fasciatus.	2001-11-01	11784019
Transformation system of Beauveria bassiana and Metarhizium anisopliae using nitrate reductase gene of Aspergillus nidulans.	2001-07	12019757
A dinoflagellate mutant with higher frequency of multiple fission.	2001	11732200

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:41:00 GMT 2025` Edited by `admin` on `Mon Mar 31 18:41:00 GMT 2025`
Record UNII	9H154DI0UP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Ethyl methanesulfonate

Systematic Name

English

NSC-26805

Preferred Name

English

Ethyl methanesulfonate [MI]

Common Name

English

Ethyl methanesulfonate [IARC]

Common Name

English

Ethyl methanesulfonate [HSDB]

Common Name

English

Ethyl methanesulphonate

Systematic Name

English

EMS

Common Name

English

Classification Tree Code System Code

IARC

Ethyl methanesulfonate

NCI_THESAURUS

C45175