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Details

Stereochemistry ACHIRAL
Molecular Formula C9H9NO4
Molecular Weight 195.1721
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-ACETYL-5-AMINOSALICYLIC ACID

SMILES

CC(=O)NC1=CC(C(O)=O)=C(O)C=C1

InChI

InChIKey=GEFDRROBUCULOD-UHFFFAOYSA-N
InChI=1S/C9H9NO4/c1-5(11)10-6-2-3-8(12)7(4-6)9(13)14/h2-4,12H,1H3,(H,10,11)(H,13,14)

HIDE SMILES / InChI

Molecular Formula C9H9NO4
Molecular Weight 195.1721
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Study of the plasma pharmacokinetics and faecal excretion of the prodrug olsalazine and its metabolites after oral administration to horses.
2002 Apr
Is your patient taking the medicine? A simple assay to measure compliance with 5-aminosalicylic acid-containing compounds.
2002 Dec
Intrarectal administration of 5-aminosalicylic acid to rabbits and dogs.
2002 Mar
Synthesis, characterization and in vitro release of 5-aminosalicylic acid and 5-acetyl aminosalicylic acid of polyanhydride--P(CBFAS).
2003 Mar
Evaluation of biotransformation of sulphasalazine in the colon epithelial Caco-2 cells.
2004 Dec
Comparative pharmacokinetics of equimolar doses of 5-aminosalicylate administered as oral mesalamine (Asacol) and balsalazide: a randomized, single-dose, crossover study in healthy volunteers.
2004 May 15
Inhibitory effect of flavonoids on N-acetylation of 5-aminosalicylic acid in cultured rat hepatocytes.
2004 Sep
Nonadherence in inflammatory bowel disease: results of factor analysis.
2007 Oct
Development and validation of a HPLC-ESI-MS/MS method for the determination of 5-aminosalicylic acid and its major metabolite N-acetyl-5-aminosalicylic acid in human plasma.
2008 Sep 1
Inhibitory effect of flavonoids on the efflux of N-acetyl 5-aminosalicylic acid intracellularly formed in Caco-2 cells.
2009
Safety, efficacy, and pharmacokinetics of balsalazide in pediatric patients with mild-to-moderate active ulcerative colitis: results of a randomized, double-blind study.
2009 Nov
Development and validation of spectrophotometric methods for the estimation of mesalamine in tablet dosage forms.
2010 Jul
Influence of 5-aminosalicylic acid on 6-thioguanosine phosphate metabolite levels: a prospective study in patients under steady thiopurine therapy.
2010 Jul
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Dec 16 09:13:35 UTC 2023
Edited
by admin
on Sat Dec 16 09:13:35 UTC 2023
Record UNII
9H126Z3PF5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
N-ACETYL-5-AMINOSALICYLIC ACID
Systematic Name English
CJ-46A
Code English
SALICYLIC ACID, 5-ACETAMIDO-
Common Name English
BENZOIC ACID, 5-(ACETYLAMINO)-2-HYDROXY-
Systematic Name English
3-CARBOXYPARACETAMOL
Systematic Name English
2-HYDROXY-5-(ACETYLAMINO)BENZOIC ACID
Systematic Name English
5-ACETAMIDOSALICYLIC ACID
Systematic Name English
ACETYLMESALAZINE
Common Name English
NSC-54183
Code English
Code System Code Type Description
EPA CompTox
DTXSID80199002
Created by admin on Sat Dec 16 09:13:36 UTC 2023 , Edited by admin on Sat Dec 16 09:13:36 UTC 2023
PRIMARY
CAS
51-59-2
Created by admin on Sat Dec 16 09:13:36 UTC 2023 , Edited by admin on Sat Dec 16 09:13:36 UTC 2023
PRIMARY
PUBCHEM
65512
Created by admin on Sat Dec 16 09:13:36 UTC 2023 , Edited by admin on Sat Dec 16 09:13:36 UTC 2023
PRIMARY
NSC
54183
Created by admin on Sat Dec 16 09:13:36 UTC 2023 , Edited by admin on Sat Dec 16 09:13:36 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-107-4
Created by admin on Sat Dec 16 09:13:36 UTC 2023 , Edited by admin on Sat Dec 16 09:13:36 UTC 2023
PRIMARY
FDA UNII
9H126Z3PF5
Created by admin on Sat Dec 16 09:13:36 UTC 2023 , Edited by admin on Sat Dec 16 09:13:36 UTC 2023
PRIMARY
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