Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H9NO4 |
| Molecular Weight | 195.1721 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)NC1=CC(C(O)=O)=C(O)C=C1
InChI
InChIKey=GEFDRROBUCULOD-UHFFFAOYSA-N
InChI=1S/C9H9NO4/c1-5(11)10-6-2-3-8(12)7(4-6)9(13)14/h2-4,12H,1H3,(H,10,11)(H,13,14)
| Molecular Formula | C9H9NO4 |
| Molecular Weight | 195.1721 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Development and validation of spectrophotometric methods for the estimation of mesalamine in tablet dosage forms. | 2010-07 |
|
| Influence of 5-aminosalicylic acid on 6-thioguanosine phosphate metabolite levels: a prospective study in patients under steady thiopurine therapy. | 2010-07 |
|
| Safety, efficacy, and pharmacokinetics of balsalazide in pediatric patients with mild-to-moderate active ulcerative colitis: results of a randomized, double-blind study. | 2009-11 |
|
| Inhibitory effect of flavonoids on the efflux of N-acetyl 5-aminosalicylic acid intracellularly formed in Caco-2 cells. | 2009 |
|
| Development and validation of a HPLC-ESI-MS/MS method for the determination of 5-aminosalicylic acid and its major metabolite N-acetyl-5-aminosalicylic acid in human plasma. | 2008-09-01 |
|
| Nonadherence in inflammatory bowel disease: results of factor analysis. | 2007-10 |
|
| Evaluation of biotransformation of sulphasalazine in the colon epithelial Caco-2 cells. | 2004-12 |
|
| Inhibitory effect of flavonoids on N-acetylation of 5-aminosalicylic acid in cultured rat hepatocytes. | 2004-09 |
|
| Comparative pharmacokinetics of equimolar doses of 5-aminosalicylate administered as oral mesalamine (Asacol) and balsalazide: a randomized, single-dose, crossover study in healthy volunteers. | 2004-05-15 |
|
| Synthesis, characterization and in vitro release of 5-aminosalicylic acid and 5-acetyl aminosalicylic acid of polyanhydride--P(CBFAS). | 2003-03 |
|
| Is your patient taking the medicine? A simple assay to measure compliance with 5-aminosalicylic acid-containing compounds. | 2002-12 |
|
| Study of the plasma pharmacokinetics and faecal excretion of the prodrug olsalazine and its metabolites after oral administration to horses. | 2002-04 |
|
| Intrarectal administration of 5-aminosalicylic acid to rabbits and dogs. | 2002-03 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:34:56 GMT 2025
by
admin
on
Mon Mar 31 22:34:56 GMT 2025
|
| Record UNII |
9H126Z3PF5
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID80199002
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51-59-2
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65512
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54183
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200-107-4
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9H126Z3PF5
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admin on Mon Mar 31 22:34:56 GMT 2025 , Edited by admin on Mon Mar 31 22:34:56 GMT 2025
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| Related Record | Type | Details | ||
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PARENT -> METABOLITE LESS ACTIVE | |||
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PARENT -> METABOLITE |
