MIPOMERSEN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Previously Marketed

First approved in 2013

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Mon Mar 31 23:08:00 GMT 2025` Edited by `admin` on `Mon Mar 31 23:08:00 GMT 2025`
Nucleic Acid Type	OLIGONUCLEOTIDE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	9GJ8S4GU0M
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MIPOMERSEN [MI]

Preferred Name

English

MIPOMERSEN

Official Name

English

MIPOMERSEN [VANDF]

Common Name

English

mipomersen [INN]

Common Name

English

Mipomersen [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

221406

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

WHO-ATC

C10AX11

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

NDF-RT

N0000191627

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

WHO-VATC

QC10AX11

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

NDF-RT

N0000191626

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

Code System Code Type Description

DRUG CENTRAL

4747

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

MESH

C524142

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

ChEMBL

CHEMBL2219536

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

SMS_ID

100000124380

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

INN

8946

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

PUBCHEM

118984467

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

WIKIPEDIA

Mipomersen

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

EPA CompTox

DTXSID10142864

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

EVMPD

SUB32496

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

LACTMED

Mipomersen

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

DRUG BANK

DB05528

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

DAILYMED

9GJ8S4GU0M

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

RXCUI

1367839

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

RxNorm

NCI_THESAURUS

C174575

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

NDF-RT

N0000011392

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

Oligonucleotides, Antisense [Chemical/Ingredient]

MERCK INDEX

m7558

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

Merck Index

IUPHAR

7364

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

FDA UNII

9GJ8S4GU0M

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

CAS

1000120-98-8

Created by admin on Mon Mar 31 23:08:00 GMT 2025 , Edited by admin on Mon Mar 31 23:08:00 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
2-O-beta-hydroxy-ethoxy-methyl Ribose (Qiagen)	1_1-1_5;1_16-1_20	10 / 20
Deoxyribose (DNA)	1_6-1_15	10 / 20

Linkage	Site Range	Site Count
Phosporothioate	1_2-1_20	19 / 19

Related Record Type Details


					18EAY4870E

MIPOMERSEN SODIUM

SALT/SOLVATE -> PARENT

Related Record Type Details


					9GJ8S4GU0M

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
BASE SUBSTITUTION	[1_12] [1_15]		CYTOSINE		5-METHYLCYTOSINE	6R795CQT4H

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:CALCULATED	CHEMICAL