U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2013
596
Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 10:14:47 UTC 2023
Edited
by admin
on Sat Dec 16 10:14:47 UTC 2023
Nucleic Acid Type OLIGONUCLEOTIDE
Nucleic Acid Subtype ANTI-SENSE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
9GJ8S4GU0M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MIPOMERSEN
DASH   INN   MI   VANDF   WHO-DD  
INN  
Official Name English
MIPOMERSEN [VANDF]
Common Name English
mipomersen [INN]
Common Name English
MIPOMERSEN [MI]
Common Name English
Mipomersen [WHO-DD]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 221406
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
WHO-ATC C10AX11
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
NDF-RT N0000191627
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
WHO-VATC QC10AX11
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
NDF-RT N0000191626
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
Code System Code Type Description
DRUG CENTRAL
4747
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
MESH
C524142
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
ChEMBL
CHEMBL2219536
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
INN
8946
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
PUBCHEM
118984467
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
WIKIPEDIA
Mipomersen
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
EPA CompTox
DTXSID10142864
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
EVMPD
SUB32496
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
LACTMED
Mipomersen
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
DRUG BANK
DB05528
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
DAILYMED
9GJ8S4GU0M
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
RXCUI
1367839
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY RxNorm
NCI_THESAURUS
C174575
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
NDF-RT
N0000011392
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY Oligonucleotides, Antisense [Chemical/Ingredient]
MERCK INDEX
m7558
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY Merck Index
IUPHAR
7364
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
FDA UNII
9GJ8S4GU0M
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
CAS
1000120-98-8
Created by admin on Sat Dec 16 10:14:47 UTC 2023 , Edited by admin on Sat Dec 16 10:14:47 UTC 2023
PRIMARY
Sugar Site Range Site Count
2-O-beta-hydroxy-ethoxy-methyl Ribose (Qiagen) 1_1-1_5;1_16-1_20 10 / 20
Deoxyribose (DNA) 1_6-1_15 10 / 20
Linkage Site Range Site Count
Phosporothioate 1_2-1_20 19 / 19
Related Record Type Details
MIPOMERSEN SODIUM
SALT/SOLVATE -> PARENT
Related Record Type Details
MIPOMERSEN
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
BASE SUBSTITUTION [1_12] [1_15] CYTOSINE 5-METHYLCYTOSINE 6R795CQT4H
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:CALCULATED CHEMICAL
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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