NITROMIDE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H5N3O5
Molecular Weight	211.1317
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

NC(=O)C1=CC(=CC(=C1)[N+]([O-])=O)[N+]([O-])=O

InChI

InChIKey=UUKWKUSGGZNXGA-UHFFFAOYSA-N

InChI=1S/C7H5N3O5/c8-7(11)4-1-5(9(12)13)3-6(2-4)10(14)15/h1-3H,(H2,8,11)

HIDE SMILES / InChI

Molecular Formula	C7H5N3O5
Molecular Weight	211.1317
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Nitromide is an anti-parasitic agent. In combination with sulfanitran (Unistat) it was used as an aid in the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, and E. acervulina.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Eimeria tenella 10	Inhibitor 8,504

Conditions

Condition	Modality	Targets	Highest Phase	Product
Coccidiosis 45	Curative		Approved 8,583	UNISTAT-2

PubMed

Show entries

Title	Date	PubMed
Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro.	1996 Dec	9039272
Pi-Pi complexation of bupivacaine and analogues with aromatic receptors: implications for overdose remediation.	2007	18019843
Continuous separation of racemic 3,5-dinitrobenzoyl-amino acids in a centrifugal contact separator with the aid of cinchona-based chiral host compounds.	2009	19142941
Charge-transfer interaction between poly(9-vinylcarbazole) and 3,5-dinitrobenzamido group or 3-nitrobenzamido group.	2010 Mar 2	19919049

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Patents

Sample Use Guides

In Vivo Use Guide

Chickens: 227 grams per ton nitromide (0.025 percent) and 272 grams per ton sulfanitran (0.03 percent).

Route of Administration: Oral

In Vitro Use Guide

Nitromide was active against Eimeria tenella at 100 ug/ml.

Substance Class	Chemical
Record UNII	9DUJ3CMK8S
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

NITROMIDE

Official Name

English

NITROMIDE [MI]

Preferred Name

English

BENZAMIDE, 3,5-DINITRO-

Systematic Name

English

NITROMIDE [USAN]

Common Name

English

UNISTAT 2 COMPONENT NITROMIDE

Common Name

English

Showing 1 to 5 of 8 entries

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Code System

Code

Type

Description

SMS_ID

300000051344

PRIMARY

CAS

121-81-3

PRIMARY

ChEMBL

CHEMBL1437065

PRIMARY

FDA UNII

9DUJ3CMK8S

PRIMARY

MESH

C008599

PRIMARY

Showing 1 to 5 of 11 entries

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