GUANCLOFINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H12Cl2N4
Molecular Weight	247.124
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of GUANCLOFINE

Structure Search

SMILES

NC(=N)NCCNC1=C(Cl)C=CC=C1Cl

InChI

InChIKey=YDDRXDOPBABLRB-UHFFFAOYSA-N

InChI=1S/C9H12Cl2N4/c10-6-2-1-3-7(11)8(6)14-4-5-15-9(12)13/h1-3,14H,4-5H2,(H4,12,13,15)

HIDE SMILES / InChI

Molecular Formula	C9H12Cl2N4
Molecular Weight	247.124
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6128849

Guanclofine was studied as an adrenergic neuron blocking agent.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Influence of adrenergic neuron blocking agents on the adrenaline-induced platelet reactions.	1982	6128849
[Effect of guanclofin on catecholamine release by the adrenal medulla].	1982 Jul-Aug	7128781

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:42:09 GMT 2023` Edited by `admin` on `Fri Dec 15 15:42:09 GMT 2023`
Record UNII	9D89762N7C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GUANCLOFINE

Official Name

English

guanclofine [INN]

Common Name

English

(2-(2,6-DICHLOROANILINO)ETHYL)GUANIDINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C270

Created by admin on Fri Dec 15 15:42:09 GMT 2023 , Edited by admin on Fri Dec 15 15:42:09 GMT 2023

Code System Code Type Description

MESH

C035768

Created by admin on Fri Dec 15 15:42:09 GMT 2023 , Edited by admin on Fri Dec 15 15:42:09 GMT 2023

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INN

3923

Created by admin on Fri Dec 15 15:42:09 GMT 2023 , Edited by admin on Fri Dec 15 15:42:09 GMT 2023

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SMS_ID

100000084473

Created by admin on Fri Dec 15 15:42:09 GMT 2023 , Edited by admin on Fri Dec 15 15:42:09 GMT 2023

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PUBCHEM

68754

Created by admin on Fri Dec 15 15:42:09 GMT 2023 , Edited by admin on Fri Dec 15 15:42:09 GMT 2023

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FDA UNII

9D89762N7C

Created by admin on Fri Dec 15 15:42:09 GMT 2023 , Edited by admin on Fri Dec 15 15:42:09 GMT 2023

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CAS

55926-23-3

Created by admin on Fri Dec 15 15:42:09 GMT 2023 , Edited by admin on Fri Dec 15 15:42:09 GMT 2023

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EVMPD

SUB07983MIG

Created by admin on Fri Dec 15 15:42:09 GMT 2023 , Edited by admin on Fri Dec 15 15:42:09 GMT 2023

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EPA CompTox

DTXSID60204527

Created by admin on Fri Dec 15 15:42:09 GMT 2023 , Edited by admin on Fri Dec 15 15:42:09 GMT 2023

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NCI_THESAURUS

C65829

Created by admin on Fri Dec 15 15:42:09 GMT 2023 , Edited by admin on Fri Dec 15 15:42:09 GMT 2023

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ChEMBL

CHEMBL2106795

Created by admin on Fri Dec 15 15:42:09 GMT 2023 , Edited by admin on Fri Dec 15 15:42:09 GMT 2023

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