U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:07:59 GMT 2023
Edited
by admin
on Sat Dec 16 15:07:59 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
9D2R4T39AY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IZURALIMAB
USAN   INN  
Official Name English
IMMUNOGLOBULIN HALF-IG G1-KAPPA/SCFV-H-CH2-CH3, ANTI-(HOMO SAPIENS ICOS (INDUCIBLE T-CELL COSTIMULATORY, ACTIVATION-INDUCIBLE LYMPHOCYTE IMMUNOMEDIATORY MOLECULE, AILIM, CD278)) AND ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), M
Common Name English
IZURALIMAB [USAN]
Common Name English
IMMUNOGLOBULIN, ANTI-(HUMAN PROGRAMMED CELL DEATH 1) (HUMAN-MUS MUSCULUS MONOCLONAL XMAB23104 SINGLE-CHAIN VARIABLE FRAGMENT VL-LINKER-VH) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN .GAMMA.1-CHAIN C-REGION C-TERMINAL FRAGMENT), (260->234'),(263->237')-
Common Name English
izuralimab [INN]
Common Name English
XMAB23104
Code English
Izuralimab [WHO-DD]
Common Name English
XMAB-23104
Code English
Code System Code Type Description
NCI_THESAURUS
C157578
Created by admin on Sat Dec 16 15:07:59 GMT 2023 , Edited by admin on Sat Dec 16 15:07:59 GMT 2023
PRIMARY
CAS
2329669-80-7
Created by admin on Sat Dec 16 15:07:59 GMT 2023 , Edited by admin on Sat Dec 16 15:07:59 GMT 2023
PRIMARY
FDA UNII
9D2R4T39AY
Created by admin on Sat Dec 16 15:07:59 GMT 2023 , Edited by admin on Sat Dec 16 15:07:59 GMT 2023
PRIMARY
INN
11466
Created by admin on Sat Dec 16 15:07:59 GMT 2023 , Edited by admin on Sat Dec 16 15:07:59 GMT 2023
PRIMARY
USAN
JK-25
Created by admin on Sat Dec 16 15:07:59 GMT 2023 , Edited by admin on Sat Dec 16 15:07:59 GMT 2023
PRIMARY
From To
1_23 1_88
1_149 1_225
1_260 2_234
1_263 2_237
1_294 1_354
1_400 1_458
2_22 2_96
2_152 2_208
2_268 2_328
2_228 3_214
2_374 2_432
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Link Type Site
N 1_330
N 2_304
Related Record Type Details
TARGET -> INHIBITOR
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL