Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H26N4.4ClH |
| Molecular Weight | 348.184 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN
InChI
InChIKey=XLDKUDAXZWHPFH-UHFFFAOYSA-N
InChI=1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
| Molecular Formula | C10H26N4 |
| Molecular Weight | 202.3402 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Reaction of superoxide and nitric oxide with peroxynitrite. Implications for peroxynitrite-mediated oxidation reactions in vivo. | 2001-08-03 |
|
| Regional distribution of ornithine decarboxylase activity and polyamine levels in experimental cat brain tumors. | 2001-08 |
|
| Genetic analysis of spermidine synthase from Leishmania donovani. | 2001-07 |
|
| Polyamine metabolism in brain tumours: diagnostic relevance of quantitative biochemistry. | 2001-07 |
|
| Polyamine depletion arrests growth of IEC-6 and Caco-2 cells by different mechanisms. | 2001-07 |
|
| Occurrence of cadaverine in hairy roots of Brugmansia candida. | 2001-07 |
|
| Effects of two photoreactive spermine analogues on peptide bond formation and their application for labeling proteins in Escherichia coli functional ribosomal complexes. | 2001-06-26 |
|
| Translocon pores in the endoplasmic reticulum are permeable to a neutral, polar molecule. | 2001-06-22 |
|
| Polyamine synthesis and interconversion by the Microsporidian Encephalitozoon cuniculi. | 2001-06-20 |
|
| Antizyme regulates the degradation of ornithine decarboxylase in fission yeast Schizosaccharomyces pombe. Study in the spe2 knockout strains. | 2001-06-15 |
|
| Chemistry of the diazeniumdiolates. 2. Kinetics and mechanism of dissociation to nitric oxide in aqueous solution. | 2001-06-13 |
|
| Different roles of spermine in glucocorticoid- and Fas-induced apoptosis. | 2001-06-10 |
|
| Chemoprevention by difluoromethylornithine: correlation of an in vitro human cell assay with human clinical data for biomarker modulation. | 2001-06-09 |
|
| Determination of polyamines in human saliva by high-performance liquid chromatography with fluorescence detection. | 2001-06-05 |
|
| Importance of the 3' untranslated region of ornithine decarboxylase mRNA in the translational regulation of the enzyme. | 2001-06-01 |
|
| Agmatine and putrescine uptake in the human glioma cell line SK-MG-1. | 2001-06 |
|
| Permeability characteristics of polyamines across intestinal epithelium using the Caco-2 monolayer system: comparison between transepithelial flux and mitogen-stimulated uptake into epithelial cells. | 2001-06 |
|
| Spermine: an "invisible" component in the crystals of B-DNA. A grand canonical Monte Carlo and molecular dynamics simulation study. | 2001-05-18 |
|
| Polyamines in the basal ganglia of human brain. Influence of aging and degenerative movement disorders. | 2001-05-18 |
|
| Spermine supports catalysis of hairpin ribozyme variants to differing extents. | 2001-05-11 |
|
| A clinical inflammatory syndrome attributable to aerosolized lipid-DNA administration in cystic fibrosis. | 2001-05-01 |
|
| Inactivation of catalase and superoxide dismutase by singlet oxygen derived from photoactivated dye. | 2001-05 |
|
| A spermine-coupled cholesterol metabolite from the shark with potent appetite suppressant and antidiabetic properties. | 2001-05 |
|
| Inhibition of Na+,K+-ATPase by interferon gamma down-regulates intestinal epithelial transport and barrier function. | 2001-05 |
|
| NF-kappaB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells. | 2001-05 |
|
| Polyamine and thiol metabolism in Trypanosoma granulosum: similarities with Trypanosoma cruzi. | 2001-04-20 |
|
| Involvement of polyamines in B cell receptor-mediated apoptosis: spermine functions as a negative modulator. | 2001-04-15 |
|
| Effect of the interaction between a low tyramine-producing Lactobacillus and proteolytic staphylococci on biogenic amine production during ripening and storage of dry sausages. | 2001-04-11 |
|
| Non-destructive quantitation of spermine in human prostate tissue samples using HRMAS 1H NMR spectroscopy at 9.4 T. | 2001-04-06 |
|
| Heme oxygenase-1 induction by nitric oxide in RAW 264.7 macrophages is upregulated by a cyclo-oxygenase-2 inhibitor. | 2001-04-03 |
|
| Intestinal ornithine decarboxylase in short bowel syndrome patients with oral diet. | 2001-04 |
|
| 5-Methoxysalicylic acid and spermine: a new matrix for the matrix-assisted laser desorption/ionization mass spectrometry analysis of oligonucleotides. | 2001-04 |
|
| Transgenic manipulation of the metabolism of polyamines in poplar cells. | 2001-04 |
|
| Spermine mediates inward rectification in potassium channels of turtle retinal Müller cells. | 2001-04 |
|
| Resistance of activated human Th2 cells to NO-induced apoptosis is mediated by gamma-glutamyltranspeptidase. | 2001-04 |
|
| Regulation of estrogenic and nuclear factor kappa B functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells. | 2001-03-29 |
|
| Polyamines secreted by cancer cells possibly account for the impairment of the human erythrocyte sodium pump activity. | 2001-03 |
|
| X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid. | 2001-03 |
|
| A mammalian sequence-dependent upstream open reading frame mediates polyamine-regulated translation in yeast. | 2001-03 |
|
| Investigation of the ternary D-myo-inositol 1,2,6-tris(phosphate)-spermine-Zn2+ system in solution. | 2001-03 |
|
| Enhancement of gene delivery by an analogue of alpha-MSH in a receptor-independent fashion. | 2001-02-09 |
|
| Methyl jasmonate upregulates biosynthetic gene expression, oxidation and conjugation of polyamines, and inhibits shoot formation in tobacco thin layers. | 2001-02 |
|
| Phosphodiester and phosphorothioate oligonucleotide condensation and preparation of antisense nanoparticles. | 2001-01-12 |
|
| Chemical, microbiological, and AromaScan evaluation of mahi-mahi fillets under various storage conditions. | 2001-01 |
|
| Influence of heavy metals on the accumulation of trimethylglycine, putrescine and spermine in food plants. | 2001 |
|
| Polyamines of the thermophilic eubacteria belonging to the genera Thermosipho, Thermaerobacter and Caldicellulosiruptor. | 2001 |
|
| Amine oxidase, spermine, and hyperthermia induce cytotoxicity in P-glycoprotein overexpressing multidrug resistant Chinese hamster ovary cells. | 2001 |
|
| Androgen responsiveness and intrarenal localization of transcripts coding for the enzymes of polyamine metabolism in the mouse. | 2001 |
|
| Polyamines of the hyperthermophilic archaebacteria belonging to the genera Thermococcus and Methanothermus and two new genera Caldivirga and Palaeococcus. | 2001 |
|
| Phase 1 study of N1-N11-diethylnorspermine (DENSPM) administered TID for 6 days in patients with advanced malignancies. | 2001 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:19:38 GMT 2025
by
admin
on
Mon Mar 31 21:19:38 GMT 2025
|
| Record UNII |
9CI1570O48
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
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DTXSID0059792
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306-67-2
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9CI1570O48
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69852
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9384
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m10140
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206-189-8
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