TOCAMPHYL

First approved in 1954

Details

Stereochemistry	EPIMERIC
Molecular Formula	C19H26O4.C4H11NO2
Molecular Weight	423.543
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCCNCCO.CC(OC(=O)[C@]1(C)CC[C@H](C(O)=O)C1(C)C)C2=CC=C(C)C=C2

InChI

InChIKey=WSEQDEFUEFCRLT-MULMSPGLSA-N

InChI=1S/C19H26O4.C4H11NO2/c1-12-6-8-14(9-7-12)13(2)23-17(22)19(5)11-10-15(16(20)21)18(19,3)4;6-3-1-5-2-4-7/h6-9,13,15H,10-11H2,1-5H3,(H,20,21);5-7H,1-4H2/t13?,15-,19+;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C4H11NO2
Molecular Weight	105.1356
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C19H26O4
Molecular Weight	318.4073
Charge	0
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	2 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7930779

Tocamphyl is a choleretic agent derived from a root extract of Curcuma longa, L. The drug was marketed in Japan, however, it is no longer available.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Biliary tract diseases 11 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1817202	Primary		Approved 8429	Gallogen Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
ABI Chem	AC1L2J87
BOC Sciences	5634-42-4	https://www.bocsci.com/tocamphyl-cas-5634-42-4-item-27676.html
ChemMol	99117238	http://www.chemmol.com/chemmol/99117238.html
Molcore	MC560674	https://www.molcore.com/product/5634-42-4
NovoSeek	21853
PubChem	21853	https://pubchem.ncbi.nlm.nih.gov/compound/21853
Smolecule	S545519	http://www.smolecule.com/products/s545519
THE BioTek	bt-285888	https://www.thebiotek.com/product/inhibitors/bt-285888
eNovation Chemicals	D671283	https://www.enovationchem.com/ProductDetails.asp?ProductID=D671283

PubMed

Title	Date	PubMed
[Effect of intraduodenal infusion of tocamphyl on pancreatic exocrine secretion and bile flow in rats].	1991 Dec	1817202
Effect of intraduodenal infusion of tocamphyl on pancreatic exocrine secretion and gastrointestinal hormone release in rats.	1994 Jun	7930779

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:11:33 UTC 2023` Edited by `admin` on `Fri Dec 15 15:11:33 UTC 2023`
Record UNII	9C8C4SBN10
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TOCAMPHYL

Official Name

English

Tocamphyl [WHO-DD]

Common Name

English

DIETHANOLAMINE SALT OF THE MONO-(+)-CAMPHORIC ACID ESTER OF P-TOLYLMETHYLCARBINOL

Common Name

English

TOCAMPHYL [USAN]

Common Name

English

TOCAMPHYL [MI]

Common Name

English

1,3-CYCLOPENTANEDICARBOXYLIC ACID, 1,2,2-TRIMETHYL-, 1-(1-(4-METHYLPHENYL)ETHYL) ESTER, COMPD. WITH 2,2'-IMINOBIS(ETHANOL) (1:1)

Common Name

English

TOCAMPHYL [JAN]

Common Name

English

tocamphyl [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66913