MIOFLAZINE HYDROCHLORIDE ANHYDROUS

Details

Stereochemistry	RACEMIC
Molecular Formula	C29H30Cl2F2N4O2.2ClH
Molecular Weight	648.399
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MIOFLAZINE HYDROCHLORIDE ANHYDROUS

Structure Search

SMILES

Cl.Cl.NC(=O)C1CN(CC(=O)NC2=C(Cl)C=CC=C2Cl)CCN1CCCC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4

InChI

InChIKey=MTGXEWVJNCWUJP-UHFFFAOYSA-N

InChI=1S/C29H30Cl2F2N4O2.2ClH/c30-24-4-1-5-25(31)28(24)35-27(38)18-36-15-16-37(26(17-36)29(34)39)14-2-3-23(19-6-10-21(32)11-7-19)20-8-12-22(33)13-9-20;;/h1,4-13,23,26H,2-3,14-18H2,(H2,34,39)(H,35,38);2*1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C29H30Cl2F2N4O2
Molecular Weight	575.477
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2332029 | https://www.ncbi.nlm.nih.gov/pubmed/1576096

Mioflazine, a calcium antagonist, was developed as a cardioprotector. It protected a human atrial muscle against the destructive effects of high concentrations of Ca2+. Information about the current study of this agent is not available.

Approval Year

PubMed

Title	Date	PubMed
Protection of human, rat, and guinea-pig atrial muscle by mioflazine, lidoflazine, and verapamil against the destructive effects of high concentrations of Ca2+.	1992-02	1576096
A comparison of the cardioprotective effects of calcium antagonists from different classes upon ischaemic damage in the guinea-pig working heart.	1989-07	2797212
[Protective effects of lidoflazine and mioflazine in ischemic myocardium].	1988-04	3197595
[Preventive effect of mioflazine on myocardial calcium-overload during postischemic reperfusion in the rabbit heart].	1988-04	3219938

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:24:18 GMT 2025` Edited by `admin` on `Mon Mar 31 21:24:18 GMT 2025`
Record UNII	9C6FZ205W8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-PIPERAZINEACETAMIDE, 3-(AMINOCARBONYL)-4-(4,4-BIS(4-FLUOROPHENYL)BUTYL)-N-(2,6-DICHLOROPHENYL)-, DIHYDROCHLORIDE

Preferred Name

English

MIOFLAZINE HYDROCHLORIDE ANHYDROUS

Common Name

English

1-PIPERAZINEACETAMIDE, 3-(AMINOCARBONYL)-4-(4,4-BIS(4-FLUOROPHENYL)BUTYL)-N-(2,6-DICHLOROPHENYL)-, HYDROCHLORIDE (1:2)

Systematic Name

English

Code System Code Type Description

PUBCHEM

3086174