PLATELET-DERIVED GROWTH FACTOR RECEPTOR BETA

Approval Year

Substance Class	Protein
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	9B09G8YMGH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PLATELET-DERIVED GROWTH FACTOR RECEPTOR BETA

Common Name

English

BETA PLATELET-DERIVED GROWTH FACTOR RECEPTOR

Preferred Name

English

CD140B

Common Name

English

PDGFR-B

Common Name

English

CD-140B

Common Name

English

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Code System

Code

Type

Description

FDA UNII

9B09G8YMGH

PRIMARY

PHAROS

P09619

PRIMARY

UNIPROT

P09619

PRIMARY

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Subunit 0

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From	To
1_22	1_68
1_117	1_158
1_203	1_259
1_404	1_476

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Glycosylation Type

HUMAN

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Glycosylation Link Type	Site
N	1_13
N	1_57
N	1_71
N	1_183
N	1_198

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Related Record

Type

Details


					M59NC4E26P

MASITINIB

INHIBITOR -> TARGET


					3P63ZTE3OY

SERALUTINIB

INHIBITOR -> TARGET

Amount:


					G6HRD2P839

Nintedanib

INHIBITOR -> TARGET


					Y6UHU32G5Z

IDRX-42

INHIBITOR -> TARGET

Qualification:

IC50

Amount:

2.6 NANOMOLAR (average)


					WD3N2P38NO

3-HYDROXY-APATINIB, TRANS-

INHIBITOR -> TARGET

Qualification:

IC50

Amount:

46.9 NANOMOLAR (average)

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Structural Modifications

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Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
	[1_530] [1_547] [1_549] [1_684] [1_708] [1_719] [1_731] [1_739] [1_743] [1_746] [1_825] [1_977] [1_989]		TYROSINE		TYROSINE O-PHOSPHATE	2R86C98KDX

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL

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