U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 17:35:46 GMT 2025
Edited
by admin
on Tue Apr 01 17:35:46 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
9AB783U039
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTIDIURETIC HORMONE RECEPTOR 1A
Preferred Name English
VASOPRESSIN V1A RECEPTOR
Common Name English
AVPR1A
Common Name English
VASCULAR/HEPATIC-TYPE ARGININE VASOPRESSIN RECEPTOR
Common Name English
AVPR V1A
Common Name English
Code System Code Type Description
FDA UNII
9AB783U039
Created by admin on Tue Apr 01 17:35:46 GMT 2025 , Edited by admin on Tue Apr 01 17:35:46 GMT 2025
PRIMARY
SMS_ID
300000009707
Created by admin on Tue Apr 01 17:35:46 GMT 2025 , Edited by admin on Tue Apr 01 17:35:46 GMT 2025
PRIMARY
UNIPROT
P37288
Created by admin on Tue Apr 01 17:35:46 GMT 2025 , Edited by admin on Tue Apr 01 17:35:46 GMT 2025
PRIMARY
From To
1_124 1_203
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_27
N 1_196
Related Record Type Details
Structure of BALOVAPTAN
INHIBITOR -> TARGET
Structure of RIBUVAPTAN
INHIBITOR -> TARGET
Structure of Invopressin
PARTIAL AGONIST->TARGET
Designed as mixed agonist-antagonist peptide selective for the vasopressin 1a (V1a) receptor with no vasopressin 2 (V2) receptor activity at therapeutic concentrations.
Structure of SKF-100273
INHIBITOR -> TARGET
BINDING
IC50
Structure of RELCOVAPTAN
INHIBITOR -> TARGET
BINDING
IC50
Structure of NERATINIB
INHIBITOR->OFF-TARGET
Structure of SELEPRESSIN
AGONIST -> TARGET
Structure of SRX-246
INHIBITOR -> TARGET
Structure of VASOPRESSIN H-3
RADIOLIGAND->TARGET
Kd
Structure of PECAVAPTAN
INHIBITOR -> TARGET
Vasopressin
AGONIST -> TARGET
BINDING
IC50
Structure of WAY-267464
INHIBITOR -> TARGET
ANTAGONIST
Structure of CONIVAPTAN
INHIBITOR -> TARGET
Structure of TC-OT-39
INHIBITOR -> TARGET
ANTAGONIST
Structure of NERATINIB
INHIBITOR -> TARGET
Structure of PF-184563
INHIBITOR -> TARGET
ANTAGONIST
Oxytocin
AGONIST -> TARGET
IC50
Structure of 2?-(7,7-Dimethylspiro[furo[3,4-b]pyridine-5(7H),4?-piperidin]-1?-yl)-1,3-dihydrospiro[2H-indene-2,5?(4?H)-oxazol]-4?-one
INHIBITOR -> TARGET
FELYPRESSIN
AGONIST -> TARGET
Structure of SRX-251
INHIBITOR -> TARGET
Structure of OPC-21268
OFF-TARGET->NON-INHIBITOR
Inhibits Rat receptor but not human
Ki

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID SUBSTITUTION [1_404] DEXFOSFOSERINE VI4F0K069V
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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