PROTEINASE-ACTIVATED RECEPTOR 1

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:46:42 UTC 2023` Edited by `admin` on `Sat Dec 16 11:46:42 UTC 2023`
Protein Type	RECEPTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	990CCI0EDF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PROTEINASE-ACTIVATED RECEPTOR 1

Common Name

English

CF2R

Common Name

English

PAR1

Common Name

English

Thrombin receptor

Common Name

English

PAR-1

Common Name

English

TR

Common Name

English

Coagulation factor II receptor

Common Name

English

Code System Code Type Description

UNIPROT

P25116

Created by admin on Sat Dec 16 11:46:42 UTC 2023 , Edited by admin on Sat Dec 16 11:46:42 UTC 2023

PRIMARY

PHAROS

P25116

Created by admin on Sat Dec 16 11:46:42 UTC 2023 , Edited by admin on Sat Dec 16 11:46:42 UTC 2023

PRIMARY

FDA UNII

990CCI0EDF

Created by admin on Sat Dec 16 11:46:42 UTC 2023 , Edited by admin on Sat Dec 16 11:46:42 UTC 2023

PRIMARY

From	To
1_134	1_213

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_21
N	1_34
N	1_209
N	1_218

Related Record Type Details


					ZCE93644N2

VORAPAXAR

INHIBITOR -> TARGET

Comments:

Blocks thrombin activation of receptor on platelets

Qualification:

Ki

Amount:


					HTI275SD2D

ATOPAXAR

INHIBITOR -> TARGET

Amount:


					25ADE2236L

THROMBIN

ACTIVATOR -> TARGET

Comments:

Cleaves the extracellular chain to unveil a new amino terminus that binds to the second transmembrane loop, causing platelet activation.

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL