CHINIOFON

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H6INO4S.CHO3.Na
Molecular Weight	435.124
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].OC([O-])=O.OC1=C(I)C=C(C2=C1N=CC=C2)S(O)(=O)=O

InChI

InChIKey=FNXKBSAUKFCXIK-UHFFFAOYSA-M

InChI=1S/C9H6INO4S.CH2O3.Na/c10-6-4-7(16(13,14)15)5-2-1-3-11-8(5)9(6)12;2-1(3)4;/h1-4,12H,(H,13,14,15);(H2,2,3,4);/q;;+1/p-1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C9H6INO4S
Molecular Weight	351.118
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	CHO3
Molecular Weight	61.0168
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/18742353 | https://www.ncbi.nlm.nih.gov/mesh/67002833

CHINIOFON, an iodoxyquinolin sulphonate derivative, is an antiprotozoal agent used in the treatment of amebiasis. It radiolabelled form can be used in radioisotope scanning.

Approval Year

PubMed

Title	Date	PubMed
Interaction of PACls with sulfate.	2004	15272715
Antineoplastic and antibacterial activity of some mononuclear Ru(II) complexes.	2004 Apr	15449735
Dual emission probe for luminescence oxygen sensing: a critical comparison between intensity, lifetime and ratiometric measurements.	2005 Apr 30	18970028
mRNA expression and localization of bNOS, eNOS and iNOS in human cervix at preterm and term labour.	2005 Aug 10	16092967
Migration and mental health in Europe (the state of the mental health in Europe working group: appendix 1).	2005 Aug 31	16135246
[Assay of three kinds of aluminum fractions (Al(a), Al(b) and Al(c)) in polynuclear aluminum solutions by Al-Ferron timed spectrophotometry and demarcation of their time limits].	2005 Feb	15852869
The modeled structure of the RNA dependent RNA polymerase of GBV-C virus suggests a role for motif E in Flaviviridae RNA polymerases.	2005 Oct 14	16225688
Effect of citric acid on aluminum hydrolytic speciation.	2005 Sep	16112170
Al(III) speciation distribution and transformation in high concentration PACl solutions.	2006	17278740
Ischemic preconditioning: protection against myocardial necrosis and apoptosis.	2007	18078014
Relative importance of hydrolyzed Al(III) species (Al(a), Al(b), and Al(c)) during coagulation with polyaluminum chloride: a case study with the typical micro-polluted source waters.	2007 Dec 15	17888935
A generalized analysis of hydrophobic and loop clusters within globular protein sequences.	2007 Jan 8	17210072
Proton-transfer compounds of 8-hydroxy-7-iodoquinoline-5-sulfonic acid (ferron) with 4-chloroaniline and 4-bromoaniline.	2007 Jul	17609572
Simulation of developmental changes in action potentials with ventricular cell models.	2007 Mar	19003434
Highly selective and sensitized spectrophotometric determination of iron (III) following potentiometric study.	2007 Sep	17970298
Enhanced coagulation with polyaluminum chlorides: role of pH/alkalinity and speciation.	2008 Apr	18328534
Glucose-insulin therapy, plasma substrate levels and cardiac recovery after cardiac ischemic events.	2008 Apr	18266096
Wake up and smell the coffee: yet another no go for cardiac patients? : editorial to "caffeinated coffee blunts the myocardial protective effects of statins against ischemia-reperfusion injury in the rat" by Ye et al.	2008 Aug	18415673
The novel adipocytokine visfatin exerts direct cardioprotective effects.	2008 Aug	18400051
OnD-CRF: predicting order and disorder in proteins using [corrected] conditional random fields.	2008 Jun 1	18430742
3-Amino-pyridinium 4-hydr-oxy-3-iodo-naphthalene-1-sulfonate dihydrate.	2008 May 17	21202620
Effect of vitamin K supplementation on insulin resistance in older men and women.	2008 Nov	18697901
[Al species distribution of organic silicate aluminum hybrid flocculants by Al-ferron complexation timed spectrophotometric method].	2008 Sep	19068635
Impaired leukocyte influx in cervix of postterm women not responding to prostaglandin priming.	2008 Sep 2	18764934
Preparation of high concentration polyaluminum chloride with high content of Alb or Alc.	2009	19999987
Hydrolysis and coagulation behavior of polyferric sulfate and ferric sulfate.	2009	19342808
Modified ferron assay for speciation characterization of hydrolyzed Al(III): a precise k value based judgment.	2009	19237778
Characterization of hydrolyzed Fe(III) species produced in Fenton's reaction.	2009 Dec 14	20184003
Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database.	2009 Dec 3	19959591
Comparison of coagulation behavior and floc structure characteristic of different polyferric-cationic polymer dual-coagulants in humic acid solution.	2009 Feb	19046756
Clustering of cancer among families of cases with Hodgkin Lymphoma (HL), Multiple Myeloma (MM), Non-Hodgkin's Lymphoma (NHL), Soft Tissue Sarcoma (STS) and control subjects.	2009 Feb 27	19250521
k-Value-based ferron assay and its application.	2009 Jul 1	19419729
Study on the hydrolysis/precipitation behavior of Keggin Al13 and Al30 polymers in polyaluminum solutions.	2009 Jun	19409689
Ethnicity and incidence of Hodgkin lymphoma in Canadian population.	2009 May 11	19432977
Transmembrane AMPA receptor regulatory proteins and AMPA receptor function in the cerebellum.	2009 Sep 1	19185052
Grand challenges in bone endocrinology.	2010	22649353
Neuronal potassium channel openers in the management of epilepsy: role and potential of retigabine.	2010	22291509
Adverse drug effects in hospitalized elderly: data from the healthcare cost and utilization project.	2010	22291486
Visfatin/PBEF/Nampt: A New Cardiovascular Target?	2010	21833174
Low HDL Cholesterol is Associated with Lower Gray Matter Volume in Cognitively Healthy Adults.	2010	20725527
[Comparative study on the coagulation of PACl with different contents of aluminum polymeric species].	2010 Aug	21090298
Using small-scale studies to prioritize threats and guide recovery of a rare hemiparasitic plant: Cordylanthus rigidus ssp. littoralis.	2010 Jan 26	20126657
Integrative physiology: defined novel metabolic roles of osteocalcin.	2010 Jul	20592887
No bones about it: insulin modulates skeletal remodeling.	2010 Jul 23	20655463
In the shadow of a new smoke free policy: A discourse analysis of health care providers' engagement in tobacco control in community mental health.	2010 Jul 28	20667105
Mutation of actin Tyr-53 alters the conformations of the DNase I-binding loop and the nucleotide-binding cleft.	2010 Mar 26	20100837
Catestatin improves post-ischemic left ventricular function and decreases ischemia/reperfusion injury in heart.	2010 Nov	21104119
Aluminum polymers formed following alum treatment of lake water.	2010 Nov	20825969
Conformational dynamics of actin: effectors and implications for biological function.	2010 Oct	20672362
The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription.	2010 Sep 16	20862324

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:45:39 GMT 2023` Edited by `admin` on `Sat Dec 16 17:45:39 GMT 2023`
Record UNII	98F8Y85B6W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CHINIOFON

Official Name

English

chiniofon [INN]

Common Name

English

NSC-758879

Code

English

A MIXTURE OF FOUR PARTS BY WEIGHT OF 8-HYDROXY-7-IODO-5-QUINOLINESULFONIC ACID AND ONE PART BY WEIGHT OF SODIUM BICARBONATE

Common Name

English

Chiniofon [WHO-DD]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QP51AX01