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Details

Stereochemistry RACEMIC
Molecular Formula C20H18N2O
Molecular Weight 302.3697
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NICOFETAMIDE

SMILES

O=C(NC(CC1=CC=CC=C1)C2=CC=CC=C2)C3=CN=CC=C3

InChI

InChIKey=DWODOIKZDGJOPQ-UHFFFAOYSA-N
InChI=1S/C20H18N2O/c23-20(18-12-7-13-21-15-18)22-19(17-10-5-2-6-11-17)14-16-8-3-1-4-9-16/h1-13,15,19H,14H2,(H,22,23)

HIDE SMILES / InChI

Molecular Formula C20H18N2O
Molecular Weight 302.3697
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Nicofetamide is the antispasmodic drug used in the treatment intestinal spasms, painful menstruation with uterine spasms, pylorospasm, habitual vomiting, and other smooth muscle spasms. Nicofetamide has also been used to facilitate and accelerate labor. Nicofetamide is administered rectally in the form of suppositories at a dosage of 400–1200 mg per day. The drug was marketed in Italy by the Bracco company.

Approval Year

Substance Class Chemical
Record UNII
9882JU353F
Record Status Validated (UNII)
Record Version