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ROPEGINTERFERON ALFA-2B
981TME683S
US Approved Rx (2021)
First approved in 2021
General
Record Details
Variant Concepts
1
Names
7
Classification
5
Identifiers
12
Subunits
1
Disulfide Links
2
Relationships
1
Active Moiety
1
Modifications
1
Characteristic Attributes
2
ROPEGINTERFERON ALFA-2B
981TME683S
US Approved Rx (2021)
First approved in 2021
General
Approval Year
2021
460
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Type
COMPLETE
Record UNII
981TME683S
Record Status
Validated (UNII)
Record Version
26
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Names
7
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entries
Name
Type
Language
Name
Type
Language
ROPEGINTERFERON ALFA-2B
Official Name
English
ropeginterferon alfa-2b [INN]
Preferred Name
English
ROPEGINTERFERON ALFA-2B [JAN]
Common Name
English
P-1101
Common Name
English
P1101
Common Name
English
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Classification
5
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Designated
ORPHAN DRUG
Designated
Treatment of myelofibrosis
FDA ORPHAN DRUG
424414
Interferons
ATC
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
IMMUNOSTIMULANTS
IMMUNOSTIMULANTS
Interferons
ropeginterferon alfa-2b
WHO-ATC
L03AB15
Designated
ORPHAN DRUG
Designated
Treatment of essential thrombocythemia
FDA ORPHAN DRUG
424514
Pegylated Interferon Alfa
Pharmacologic Substance
[C1909]
Antineoplastic Agent
[C274]
Angiogenesis Inhibitor
[C1742]
Angiogenesis Activator Inhibitor
[C1971]
Recombinant Interferon Alfa
[C225]
Pegylated Interferon Alfa
[C2491]
Peginterferon Alfa-2b
NCI_THESAURUS
C1845
Designated/Approved
ORPHAN DRUG
Designated/Approved
Treatment of polycythemia vera
FDA ORPHAN DRUG
367012
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Identifiers
12
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Code System
Code
Type
Description
Code System
Code
Type
Description
RXCUI
2587059
PRIMARY
NCI_THESAURUS
C152250
ALTERNATIVE
INN
9683
PRIMARY
DRUG BANK
DB15119
PRIMARY
PUBCHEM
86278347
PRIMARY
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Subunits
1
Disulfide Links
2
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From
To
From
To
1_2
1_99
1_30
1_139
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Relationships
1
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Related Record
Type
Details
Related Record
Type
Details
ROPEGINTERFERON ALFA-2B-NJFT
SUB_CONCEPT->SUBSTANCE
Amount:
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Active Moiety
1
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Details
Related Record
Type
Details
981TME683S
ROPEGINTERFERON ALFA-2B
ACTIVE MOIETY
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Modifications
1
Structural Modifications
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Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
AMINO_ACID_SUBSTITUTION
[1_1]
N-TERMINUS
Pro
UNSPECIFIED SUBSTANCE
065be31c
(not in database)
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Characteristic Attributes
2
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Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:NUMBER AVERAGE
CHEMICAL
ESTIMATED 60000 DALTONS (average)
Molecular Formula
CHEMICAL
ESTIMATED
C860H1349N229O255S9
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