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Details

Stereochemistry ABSOLUTE
Molecular Formula C28H35N5O5
Molecular Weight 521.608
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MORPHICEPTIN

SMILES

N[C@@H](CC1=CC=C(O)C=C1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N4CCC[C@H]4C(N)=O

InChI

InChIKey=LSQXZIUREIDSHZ-ZJZGAYNASA-N
InChI=1S/C28H35N5O5/c29-21(16-19-10-12-20(34)13-11-19)27(37)33-15-5-9-24(33)26(36)31-22(17-18-6-2-1-3-7-18)28(38)32-14-4-8-23(32)25(30)35/h1-3,6-7,10-13,21-24,34H,4-5,8-9,14-17,29H2,(H2,30,35)(H,31,36)/t21-,22-,23-,24-/m0/s1

HIDE SMILES / InChI

Molecular Formula C28H35N5O5
Molecular Weight 521.608
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Morphiceptin (Tyr-Pro-Phe-Pro-NH2), an amide of a fragment of the milk protein beta-casein, is a selective ligand of the mu opioid receptor, an important target in pain regulation. Now is used the analogs of morphiceptin, which are studied for the treatment of different diseases.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
97TZA8ANPC
Record Status Validated (UNII)
Record Version