U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C9H18O2
Molecular Weight 158.238
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PELARGONIC ACID

SMILES

CCCCCCCCC(O)=O

InChI

InChIKey=FBUKVWPVBMHYJY-UHFFFAOYSA-N
InChI=1S/C9H18O2/c1-2-3-4-5-6-7-8-9(10)11/h2-8H2,1H3,(H,10,11)

HIDE SMILES / InChI

Molecular Formula C9H18O2
Molecular Weight 158.238
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Pelargonic acid (also called as nonanoic acid), a naturally found in a variety of plants and food products is a cosmetic ingredient, that function as skin-conditioning agent. The Food and Drug Administration (FDA) has approved pelargonic acid as a food additive, and as an ingredient in solutions used commercially to peel fruits and vegetables. FDA considers it safe for humans to eat food containing small amounts of pelargonic acid.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Cytotoxic butanolides from the stem bark of Formosan Lindera communis.
2001 Dec
[Determination of organic acids in cigarette smoke].
2001 Jul
Cometabolic biosynthesis of copolyesters consisting of 3-hydroxyvalerate and medium-chain-length 3-hydroxyalkanoates by Pseudomonas sp. DSY-82.
2001 Oct
Biosynthesis of polyhydroxyalkanoate copolyester containing cyclohexyl groups by Pseudomonas oleovorans.
2001 Oct 22
Increase in meningeal blood flow by nitric oxide--interaction with calcitonin gene-related peptide receptor and prostaglandin synthesis inhibition.
2002 Apr
Dietary antioxidants preserve endothelium dependent vasorelaxation in overfed rats.
2002 Apr
NO donors potentiate the beta-adrenergic stimulation of I(Ca,L) and the muscarinic activation of I(K,ACh) in rat cardiac myocytes.
2002 Apr 15
Nitric oxide of human colorectal adenocarcinoma cell lines promotes tumour cell invasion.
2002 Apr 22
Nitrosation and nitration of 2-amino-3-methylimidazo[4,5-f]quinoline by reactive nitrogen oxygen species.
2002 Aug
The effects of inhalation of a novel nitric oxide donor, DETA/NO, in a patient with severe hypoxaemia due to acute respiratory distress syndrome.
2002 Aug
Skin irritation typing and grading based on laser Doppler perfusion imaging.
2002 Feb
Nitric oxide blocks fast, slow, and persistent Na+ channels in C-type DRG neurons by S-nitrosylation.
2002 Feb
Self-assembled vesicles of monocarboxylic acids and alcohols: conditions for stability and for the encapsulation of biopolymers.
2002 Feb 10
Attractant volatiles released by female and male Triatoma infestans (Hemiptera: Reduviidae), a vector of chagas disease: chemical analysis and behavioral bioassay.
2002 Jan
Soluble guanylyl cyclase activator YC-1 protects white matter axons from nitric oxide toxicity and metabolic stress, probably through Na(+) channel inhibition.
2002 Jan
The synthesis of short- and medium-chain-length poly(hydroxyalkanoate) mixtures from glucose- or alkanoic acid-grown Pseudomonas oleovorans.
2002 Mar
Proteomic analysis of skin irritation reveals the induction of HSP27 by sodium lauryl sulphate in human skin.
2002 May
A new and simple method for delivering clamped nitric oxide concentrations in the physiological range: application to activation of guanylyl cyclase-coupled nitric oxide receptors.
2003 Dec
Air quality model evaluation data for organics. 6. C3-C24 organic acids.
2003 Feb 1
Effect of nitric oxide on excitatory amino acid-evoked discharge of neurons in NTS.
2003 Jan
Binary phase equilibria of three alpha-methyl-substituted sodium alkanoate surfactants.
2003 Jan 15
Superoxide-dependent consumption of nitric oxide in biological media may confound in vitro experiments.
2003 Jan 15
[Effects of reactive species of oxygen and nitrogen on iron ion release from ferritin and synthesis of dinitrosyl iron complexes].
2003 Jan-Feb
Assessment of irritant skin reactions using electrical impedance--a comparison between 2 laboratories.
2003 Jul
Superoxide-NO interaction decreases flow- and agonist-induced dilations of coronary arterioles in Type 2 diabetes mellitus.
2003 Oct
Nonanoic acid--an experimental irritant.
2003 Sep
On the regulation of NMDA receptors by nitric oxide.
2004 Apr
Extract of the seed coat of Tamarindus indica inhibits nitric oxide production by murine macrophages in vitro and in vivo.
2004 Apr
Combination therapy of stroke in rats with a nitric oxide donor and human bone marrow stromal cells enhances angiogenesis and neurogenesis.
2004 Apr 16
Selectivity and stability of organic films at the air-aqueous interface.
2004 Dec 1
In-vitro anti-inflammatory effect of Eucalyptus globulus and Thymus vulgaris: nitric oxide inhibition in J774A.1 murine macrophages.
2004 Feb
Effects of odd-numbered medium-chain fatty acids on the accumulation of long-chain 3-hydroxy-fatty acids in long-chain L-3-hydroxyacyl CoA dehydrogenase and mitochondrial trifunctional protein deficient skin fibroblasts.
2004 Feb
Nitric oxide decreases the biological activity of norepinephrine resulting in altered vascular tone in the rat mesenteric arterial bed.
2004 Jan
Position in cell cycle controls the sensitivity of colon cancer cells to nitric oxide-dependent programmed cell death.
2004 Jun 15
Basal nitric oxide production contributes to membrane potential and vasotone regulation of guinea pig in vitro spiral modiolar artery.
2004 Mar
cGMP-generating cells in the bladder wall: identification of distinct networks of interstitial cells.
2004 Nov
Differential mechanisms of nitric oxide- and peroxynitrite-induced cell death.
2004 Oct
[Studies on synthesis of polyhydroxyalkanoate consisting of 3-hydroxyvalerate by Aeromonas hydrophila].
2004 Sep
Semiochemistry of the goldeneyed lacewing Chrysopa oculata: attraction of males to a male-produced pheromone.
2004 Sep
Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis.
2005 Apr
Differential role of nitric oxide in regional sympathetic responses to stimulation of NTS A2a adenosine receptors.
2005 Feb
NO-cGMP signaling molecules in cells of the rat molar dentin-pulp complex.
2005 Jul
Mechanism of neopterin-induced myocardial dysfunction in the isolated perfused rat heart.
2005 Jun 20
Sex difference in nitric oxide synthase-dependent dilatation of cerebral arterioles during long-term alcohol consumption.
2005 Mar
Effects of a nebulized NONOate, DPTA/NO, on group B streptococcus-induced pulmonary hypertension in newborn piglets.
2005 Mar
Antifeedants against Hylobius abietis pine weevils: an active compound in extract of bark of Tilia cordata linden.
2005 May
Enhanced odor discrimination and impaired olfactory memory by spatially controlled switch of AMPA receptors.
2005 Nov
Role of SGK1 in nitric oxide inhibition of ENaC in Na+-transporting epithelia.
2005 Sep
Cerebral vascular effects of angiotensin II: new insights from genetic models.
2006 Apr
Thermal stabilization of human albumin by medium- and short-chain n-alkyl fatty acid anions.
2006 Mar
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Wed Jul 05 22:43:51 UTC 2023
Edited
by admin
on Wed Jul 05 22:43:51 UTC 2023
Record UNII
97SEH7577T
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PELARGONIC ACID
INCI   MI  
INCI  
Official Name English
PELARGONIC ACID [MI]
Common Name English
NONOIC ACID
Common Name English
NONANOIC ACID
FCC   FHFI   HSDB  
Systematic Name English
FEMA NO. 2784
Code English
NONANOIC ACID [FCC]
Common Name English
PELARGONIC ACID [INCI]
Common Name English
NSC-62787
Code English
GRANTRICO
Common Name English
NSC-65450
Code English
NONANOIC ACID [HSDB]
Common Name English
THINEX
Common Name English
NSC-65455
Code English
1-OCTANECARBOXYLIC ACID
Systematic Name English
NONYLIC ACID
Common Name English
NONANOIC ACID [FHFI]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 217500
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
CFR 21 CFR 172.515
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
NCI_THESAURUS C541
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
JECFA EVALUATION NONANOIC ACID
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
Code System Code Type Description
EPA CompTox
DTXSID3021641
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
FDA UNII
97SEH7577T
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
ALANWOOD
pelargonic acid
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
PUBCHEM
8158
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
CHEBI
32361
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
DAILYMED
97SEH7577T
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
HSDB
5554
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
CAS
112-05-0
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
RXCUI
2054105
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
MERCK INDEX
M8449
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY Merck Index
NSC
65450
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
CHEBI
29019
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
NSC
65455
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
NCI_THESAURUS
C82932
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
NSC
62787
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
WIKIPEDIA
NONANOIC ACID
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
ECHA (EC/EINECS)
203-931-2
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
RXCUI
2054104
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
ALTERNATIVE
MESH
C008776
Created by admin on Wed Jul 05 22:43:51 UTC 2023 , Edited by admin on Wed Jul 05 22:43:51 UTC 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
PARENT -> CONSTITUENT ALWAYS PRESENT
Compound measured as 1.80% of the composition of the steam distillate of Elymus repens rhizome as per R Boesel in Planta Medica iss:4 pg:399-400, 1989.
Related Record Type Details
ACTIVE MOIETY