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Details

Stereochemistry ACHIRAL
Molecular Formula C9H18O2
Molecular Weight 158.2384
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PELARGONIC ACID

SMILES

CCCCCCCCC(=O)O

InChI

InChIKey=FBUKVWPVBMHYJY-UHFFFAOYSA-N
InChI=1S/C9H18O2/c1-2-3-4-5-6-7-8-9(10)11/h2-8H2,1H3,(H,10,11)

HIDE SMILES / InChI

Molecular Formula C9H18O2
Molecular Weight 158.2384
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Pelargonic acid (also called as nonanoic acid), a naturally found in a variety of plants and food products is a cosmetic ingredient, that function as skin-conditioning agent. The Food and Drug Administration (FDA) has approved pelargonic acid as a food additive, and as an ingredient in solutions used commercially to peel fruits and vegetables. FDA considers it safe for humans to eat food containing small amounts of pelargonic acid.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Lipolytic and esterolytic activities in posterior lingual glands of rat: a histochemical study.
2002
Autoantibody-mediated atherosclerosis.
2002 Dec
Attraction of Amblyomma variegatum (ticks) to the attraction-aggregation-attachment-pheromone with or without carbon dioxide.
2003
Cyclic GMP mediates influence of macula densa nitric oxide over tubuloglomerular feedback.
2003
Upregulation of neurogenesis and reduction in functional deficits following administration of DEtA/NONOate, a nitric oxide donor, after traumatic brain injury in rats.
2003 Aug
Role of intrinsic nitrergic neurones on vagally mediated striated muscle contractions in the hamster oesophagus.
2003 Aug 15
A new and simple method for delivering clamped nitric oxide concentrations in the physiological range: application to activation of guanylyl cyclase-coupled nitric oxide receptors.
2003 Dec
Binary phase equilibria of three alpha-methyl-substituted sodium alkanoate surfactants.
2003 Jan 15
Assessment of irritant skin reactions using electrical impedance--a comparison between 2 laboratories.
2003 Jul
The effect of a glucocorticoid on olfactory response of isolated mouse olfactory cells.
2003 Jul-Aug
Mammary blood flow does not limit milk yield in lactating goats.
2003 Jun
[Neuropeptide release in the dura mater encephali in response to nitric oxide--relevance for the development of vascular headaches?].
2003 Jun
Contributions of endothelial and neuronal nitric oxide synthases to cerebrovascular responses to hyperoxia.
2003 Oct
Superoxide-NO interaction decreases flow- and agonist-induced dilations of coronary arterioles in Type 2 diabetes mellitus.
2003 Oct
Nonanoic acid--an experimental irritant.
2003 Sep
Photoelectron resonance capture ionization mass spectrometry: a soft ionization source for mass spectrometry of particle-phase organic compounds.
2004
The effect of a nebulized NO donor, DPTA/NO, on acute hypoxic pulmonary hypertension in newborn piglets.
2004
On the regulation of NMDA receptors by nitric oxide.
2004 Apr
Extract of the seed coat of Tamarindus indica inhibits nitric oxide production by murine macrophages in vitro and in vivo.
2004 Apr
Combination therapy of stroke in rats with a nitric oxide donor and human bone marrow stromal cells enhances angiogenesis and neurogenesis.
2004 Apr 16
Selectivity and stability of organic films at the air-aqueous interface.
2004 Dec 1
Formulation and in vitro evaluation of transdermal patches of melatonin.
2004 Feb
In-vitro anti-inflammatory effect of Eucalyptus globulus and Thymus vulgaris: nitric oxide inhibition in J774A.1 murine macrophages.
2004 Feb
Effects of odd-numbered medium-chain fatty acids on the accumulation of long-chain 3-hydroxy-fatty acids in long-chain L-3-hydroxyacyl CoA dehydrogenase and mitochondrial trifunctional protein deficient skin fibroblasts.
2004 Feb
PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes.
2004 Feb
Nitric oxide decreases the biological activity of norepinephrine resulting in altered vascular tone in the rat mesenteric arterial bed.
2004 Jan
Position in cell cycle controls the sensitivity of colon cancer cells to nitric oxide-dependent programmed cell death.
2004 Jun 15
Angeli's salt and spinal motor neuron injury.
2004 Mar
Basal nitric oxide production contributes to membrane potential and vasotone regulation of guinea pig in vitro spiral modiolar artery.
2004 Mar
Oral prednisone suppresses allergic but not irritant patch test reactions in individuals hypersensitive to nickel.
2004 May
cGMP-generating cells in the bladder wall: identification of distinct networks of interstitial cells.
2004 Nov
Differential mechanisms of nitric oxide- and peroxynitrite-induced cell death.
2004 Oct
[Studies on synthesis of polyhydroxyalkanoate consisting of 3-hydroxyvalerate by Aeromonas hydrophila].
2004 Sep
Semiochemistry of the goldeneyed lacewing Chrysopa oculata: attraction of males to a male-produced pheromone.
2004 Sep
Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis.
2005 Apr
Purification and characterization of cytochrome c' from Neisseria meningitidis.
2005 Feb
Differential role of nitric oxide in regional sympathetic responses to stimulation of NTS A2a adenosine receptors.
2005 Feb
NO-cGMP signaling molecules in cells of the rat molar dentin-pulp complex.
2005 Jul
The vasoactive peptide adrenomedullin is secreted by adipocytes and inhibits lipolysis through NO-mediated beta-adrenergic agonist oxidation.
2005 Jun
Mechanism of neopterin-induced myocardial dysfunction in the isolated perfused rat heart.
2005 Jun 20
Sex difference in nitric oxide synthase-dependent dilatation of cerebral arterioles during long-term alcohol consumption.
2005 Mar
Nitric oxide synthase in the gill of Atlantic salmon: colocalization with and inhibition of Na+,K+-ATPase.
2005 Mar
CGRP release and c-fos expression within trigeminal nucleus caudalis of the rat following glyceryltrinitrate infusion.
2005 Mar
Effects of a nebulized NONOate, DPTA/NO, on group B streptococcus-induced pulmonary hypertension in newborn piglets.
2005 Mar
Antifeedants against Hylobius abietis pine weevils: an active compound in extract of bark of Tilia cordata linden.
2005 May
Analysis of nitric oxide donor effectiveness in resistance vessels.
2005 May
Enhanced odor discrimination and impaired olfactory memory by spatially controlled switch of AMPA receptors.
2005 Nov
Role of SGK1 in nitric oxide inhibition of ENaC in Na+-transporting epithelia.
2005 Sep
Cerebral vascular effects of angiotensin II: new insights from genetic models.
2006 Apr
Thermal stabilization of human albumin by medium- and short-chain n-alkyl fatty acid anions.
2006 Mar
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Jun 26 13:44:25 UTC 2021
Edited
by admin
on Sat Jun 26 13:44:25 UTC 2021
Record UNII
97SEH7577T
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PELARGONIC ACID
INCI   MI  
INCI  
Official Name English
PELARGONIC ACID [MI]
Common Name English
NONOIC ACID
Common Name English
NONANOIC ACID
FCC   FHFI   HSDB  
Systematic Name English
FEMA NO. 2784
Code English
NONANOIC ACID [FCC]
Common Name English
PELARGONIC ACID [INCI]
Common Name English
NSC-62787
Code English
GRANTRICO
Common Name English
NSC-65450
Code English
NONANOIC ACID [HSDB]
Common Name English
THINEX
Common Name English
NSC-65455
Code English
1-OCTANECARBOXYLIC ACID
Systematic Name English
NONYLIC ACID
Common Name English
NONANOIC ACID [FHFI]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 217500
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
CFR 21 CFR 172.515
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
NCI_THESAURUS C541
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
JECFA EVALUATION NONANOIC ACID
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
Code System Code Type Description
EPA CompTox
112-05-0
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
PRIMARY
FDA UNII
97SEH7577T
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
PRIMARY
PUBCHEM
8158
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
PRIMARY
HSDB
5554
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
PRIMARY
CAS
112-05-0
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
PRIMARY
RXCUI
2054105
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
PRIMARY
MERCK INDEX
M8449
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
PRIMARY Merck Index
NCI_THESAURUS
C82932
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
PRIMARY
WIKIPEDIA
NONANOIC ACID
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
PRIMARY
ECHA (EC/EINECS)
203-931-2
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
PRIMARY
RXCUI
2054104
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
ALTERNATIVE
MESH
C008776
Created by admin on Sat Jun 26 13:44:25 UTC 2021 , Edited by admin on Sat Jun 26 13:44:25 UTC 2021
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
PARENT -> CONSTITUENT ALWAYS PRESENT
Compound measured as 1.80% of the composition of the steam distillate of Elymus repens rhizome as per R Boesel in Planta Medica iss:4 pg:399-400, 1989.
Related Record Type Details
ACTIVE MOIETY