Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H18O2 |
| Molecular Weight | 158.238 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCCC(O)=O
InChI
InChIKey=FBUKVWPVBMHYJY-UHFFFAOYSA-N
InChI=1S/C9H18O2/c1-2-3-4-5-6-7-8-9(10)11/h2-8H2,1H3,(H,10,11)
| Molecular Formula | C9H18O2 |
| Molecular Weight | 158.238 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Pelargonic acid (also called as nonanoic acid), a naturally found in a variety of plants and food products is a cosmetic ingredient, that function as skin-conditioning agent. The Food and Drug Administration (FDA) has approved pelargonic acid as a food additive, and as an ingredient in solutions used commercially to peel fruits and vegetables. FDA considers it safe for humans to eat food containing small amounts of pelargonic acid.
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
Sources: https://www.ncbi.nlm.nih.gov/pubmed/23177536 |
Primary | Unknown Approved UseUnknown |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Cerebral vascular effects of angiotensin II: new insights from genetic models. | 2006-04 |
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| Thermal stabilization of human albumin by medium- and short-chain n-alkyl fatty acid anions. | 2006-03 |
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| Enhanced odor discrimination and impaired olfactory memory by spatially controlled switch of AMPA receptors. | 2005-11 |
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| Role of SGK1 in nitric oxide inhibition of ENaC in Na+-transporting epithelia. | 2005-09 |
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| NO-cGMP signaling molecules in cells of the rat molar dentin-pulp complex. | 2005-07 |
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| Mechanism of neopterin-induced myocardial dysfunction in the isolated perfused rat heart. | 2005-06-20 |
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| The vasoactive peptide adrenomedullin is secreted by adipocytes and inhibits lipolysis through NO-mediated beta-adrenergic agonist oxidation. | 2005-06 |
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| Antifeedants against Hylobius abietis pine weevils: an active compound in extract of bark of Tilia cordata linden. | 2005-05 |
|
| Analysis of nitric oxide donor effectiveness in resistance vessels. | 2005-05 |
|
| Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis. | 2005-04 |
|
| Sex difference in nitric oxide synthase-dependent dilatation of cerebral arterioles during long-term alcohol consumption. | 2005-03 |
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| Nitric oxide synthase in the gill of Atlantic salmon: colocalization with and inhibition of Na+,K+-ATPase. | 2005-03 |
|
| CGRP release and c-fos expression within trigeminal nucleus caudalis of the rat following glyceryltrinitrate infusion. | 2005-03 |
|
| Effects of a nebulized NONOate, DPTA/NO, on group B streptococcus-induced pulmonary hypertension in newborn piglets. | 2005-03 |
|
| Purification and characterization of cytochrome c' from Neisseria meningitidis. | 2005-02 |
|
| Differential role of nitric oxide in regional sympathetic responses to stimulation of NTS A2a adenosine receptors. | 2005-02 |
|
| Selectivity and stability of organic films at the air-aqueous interface. | 2004-12-01 |
|
| cGMP-generating cells in the bladder wall: identification of distinct networks of interstitial cells. | 2004-11 |
|
| Differential mechanisms of nitric oxide- and peroxynitrite-induced cell death. | 2004-10 |
|
| [Studies on synthesis of polyhydroxyalkanoate consisting of 3-hydroxyvalerate by Aeromonas hydrophila]. | 2004-09 |
|
| Semiochemistry of the goldeneyed lacewing Chrysopa oculata: attraction of males to a male-produced pheromone. | 2004-09 |
|
| Position in cell cycle controls the sensitivity of colon cancer cells to nitric oxide-dependent programmed cell death. | 2004-06-15 |
|
| Oral prednisone suppresses allergic but not irritant patch test reactions in individuals hypersensitive to nickel. | 2004-05 |
|
| Combination therapy of stroke in rats with a nitric oxide donor and human bone marrow stromal cells enhances angiogenesis and neurogenesis. | 2004-04-16 |
|
| On the regulation of NMDA receptors by nitric oxide. | 2004-04 |
|
| Extract of the seed coat of Tamarindus indica inhibits nitric oxide production by murine macrophages in vitro and in vivo. | 2004-04 |
|
| Angeli's salt and spinal motor neuron injury. | 2004-03 |
|
| Basal nitric oxide production contributes to membrane potential and vasotone regulation of guinea pig in vitro spiral modiolar artery. | 2004-03 |
|
| Formulation and in vitro evaluation of transdermal patches of melatonin. | 2004-02 |
|
| In-vitro anti-inflammatory effect of Eucalyptus globulus and Thymus vulgaris: nitric oxide inhibition in J774A.1 murine macrophages. | 2004-02 |
|
| Effects of odd-numbered medium-chain fatty acids on the accumulation of long-chain 3-hydroxy-fatty acids in long-chain L-3-hydroxyacyl CoA dehydrogenase and mitochondrial trifunctional protein deficient skin fibroblasts. | 2004-02 |
|
| PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes. | 2004-02 |
|
| Nitric oxide decreases the biological activity of norepinephrine resulting in altered vascular tone in the rat mesenteric arterial bed. | 2004-01 |
|
| Photoelectron resonance capture ionization mass spectrometry: a soft ionization source for mass spectrometry of particle-phase organic compounds. | 2004 |
|
| The effect of a nebulized NO donor, DPTA/NO, on acute hypoxic pulmonary hypertension in newborn piglets. | 2004 |
|
| A new and simple method for delivering clamped nitric oxide concentrations in the physiological range: application to activation of guanylyl cyclase-coupled nitric oxide receptors. | 2003-12 |
|
| Contributions of endothelial and neuronal nitric oxide synthases to cerebrovascular responses to hyperoxia. | 2003-10 |
|
| Superoxide-NO interaction decreases flow- and agonist-induced dilations of coronary arterioles in Type 2 diabetes mellitus. | 2003-10 |
|
| Nonanoic acid--an experimental irritant. | 2003-09 |
|
| The effect of a glucocorticoid on olfactory response of isolated mouse olfactory cells. | 2003-08-22 |
|
| Role of intrinsic nitrergic neurones on vagally mediated striated muscle contractions in the hamster oesophagus. | 2003-08-15 |
|
| Upregulation of neurogenesis and reduction in functional deficits following administration of DEtA/NONOate, a nitric oxide donor, after traumatic brain injury in rats. | 2003-08 |
|
| Assessment of irritant skin reactions using electrical impedance--a comparison between 2 laboratories. | 2003-07 |
|
| Mammary blood flow does not limit milk yield in lactating goats. | 2003-06 |
|
| [Neuropeptide release in the dura mater encephali in response to nitric oxide--relevance for the development of vascular headaches?]. | 2003-06 |
|
| Binary phase equilibria of three alpha-methyl-substituted sodium alkanoate surfactants. | 2003-01-15 |
|
| Attraction of Amblyomma variegatum (ticks) to the attraction-aggregation-attachment-pheromone with or without carbon dioxide. | 2003 |
|
| Cyclic GMP mediates influence of macula densa nitric oxide over tubuloglomerular feedback. | 2003 |
|
| Autoantibody-mediated atherosclerosis. | 2002-12 |
|
| Lipolytic and esterolytic activities in posterior lingual glands of rat: a histochemical study. | 2002 |
| Substance Class |
Chemical
Created
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admin
on
Edited
Wed Apr 02 18:45:43 GMT 2025
by
admin
on
Wed Apr 02 18:45:43 GMT 2025
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| Record UNII |
97SEH7577T
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| Record Status |
Validated (UNII)
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| Classification Tree | Code System | Code | ||
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EPA PESTICIDE CODE |
217500
Created by
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CFR |
21 CFR 172.515
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NCI_THESAURUS |
C541
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JECFA EVALUATION |
NONANOIC ACID
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DTXSID3021641
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97SEH7577T
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pelargonic acid
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8158
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272
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32361
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97SEH7577T
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5554
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112-05-0
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2054105
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m8449
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PRIMARY | Merck Index | ||
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65450
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29019
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65455
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C82932
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62787
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NONANOIC ACID
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203-931-2
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2054104
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C008776
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SALT/SOLVATE -> PARENT |
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PARENT -> CONSTITUENT ALWAYS PRESENT |
Compound measured as 1.80% of the composition of the steam distillate of Elymus repens rhizome as per R Boesel in Planta Medica iss:4 pg:399-400, 1989.
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ACTIVE MOIETY |
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