CEFAZAFLUR

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C13H13F3N6O4S3
Molecular Weight	470.47
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@H]2NC(=O)CSC(F)(F)F)C(O)=O

InChI

InChIKey=HGXLJRWXCXSEJO-GMSGAONNSA-N

InChI=1S/C13H13F3N6O4S3/c1-21-12(18-19-20-21)28-3-5-2-27-10-7(9(24)22(10)8(5)11(25)26)17-6(23)4-29-13(14,15)16/h7,10H,2-4H2,1H3,(H,17,23)(H,25,26)/t7-,10-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C13H13F3N6O4S3
Molecular Weight	470.47
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2569531 | https://www.ncbi.nlm.nih.gov/pubmed/313753 | https://www.ncbi.nlm.nih.gov/pubmed/26651 | https://www.ncbi.nlm.nih.gov/pubmed/924896

Cefazaflur (INN) is a semisynthetic first-generation cephalosporin antibiotic patented by Smithkline Corp. For treatment of bacterial infections.

Originator

Approval Year

PubMed

Title	Date	PubMed
In vitro studies with cefazaflur and other parenteral cephalosporins.	1977 Sep	924896

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:18:29 GMT 2023` Edited by `admin` on `Sat Dec 16 17:18:29 GMT 2023`
Record UNII	97I0692RNT
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CEFAZAFLUR

Official Name

English

cefazaflur [INN]

Common Name

English

(6R,7R)-3-(((1-METHYL-1H-TETRAZOL-5-YL)THIO)METHYL)-8-OXO-7-(2-((TRIFLUOROMETHYL)THIO)ACETAMIDO)-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLATE

Systematic Name

English

5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 3-(((1-METHYL-1H-TETRAZOL-5-YL)THIO)METHYL)-8-OXO-7-((((TRIFLUOROMETHYL)THIO)ACETYL)AMINO)-, (6R-TRANS)-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C357