SEBACIC ACID

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H18O4
Molecular Weight	202.2475
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CCCCCCCCC(O)=O

InChI

InChIKey=CXMXRPHRNRROMY-UHFFFAOYSA-N

InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14)

HIDE SMILES / InChI

Molecular Formula	C10H18O4
Molecular Weight	202.2475
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Acne 100 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=79f8fc90-2447-4224-ac79-1645d1c82d4f	Inactive ingredient		Approved 8583	KLEER-PLEX ADVANCED ACNE CARE SYSTEM Approved Use Acne Treatment. - For the management of acne. - Clears up most acne pimples, blackheads, and whiteheads and allows skin to heal. - Penetrates pores to eliminate most acne blemishes. - Helps prevent new acne pimples.

PubMed

Title	Date	PubMed
μ-Decane-dioato-bis-[aqua-bis-(1,10-phenanthroline-κN,N')manganese(II)] dinitrate-sebacic acid-water (1/1/2).	2010-12-15	21522598
Six weeks' sebacic acid supplementation improves fasting plasma glucose, HbA1c and glucose tolerance in db/db mice.	2010-12	20977585
Polyethylene sebacate-doxorubicin nanoparticles for hepatic targeting.	2010-11-30	20854883
Effect of oral sebacic Acid on postprandial glycemia, insulinemia, and glucose rate of appearance in type 2 diabetes.	2010-11	20724647
catena-Poly[[[1,2-bis-(benzimidazol-2-yl)ethane]cadmium(II)]-μ-sebacato].	2010-03-13	21580506
Glycolic acid modulates the mechanical property and degradation of poly(glycerol, sebacate, glycolic acid).	2010-01	19189387
Degradation behavior of poly(glycerol sebacate).	2009-12-15	19107788
Polyethylene sebacate: genotoxicity, mutagenicity evaluation and application in periodontal drug delivery system.	2009-12	19455616
Production of bioactive metabolites by Nocardia levis MK-VL_113.	2009-10	19708882
2-Amino-6-methyl-1,3-benzothia-zole-deca-nedioic acid (2/1).	2009-08-19	21577592
Paraquat induces oxidative stress, neuronal loss in substantia nigra region and parkinsonism in adult rats: neuroprotection and amelioration of symptoms by water-soluble formulation of coenzyme Q10.	2009-07-27	19635141
Medium-chain fatty acids and glutathione derivatives as inhibitors of S-nitrosoglutathione reduction mediated by alcohol dehydrogenase 3.	2009-06-15	19428350
Inhaled steroid/tobacco smoke particle interactions: a new light on steroid resistance.	2009-06-11	19519905
Sampling and analysis of nanoparticles with cold fibre SPME device.	2009-06	19425018
Influence of Honey on the Suppression of Human Low Density Lipoprotein (LDL) Peroxidation (In vitro).	2009-03	18955249
Nanoparticles of polyethylene sebacate: a new biodegradable polymer.	2009	19629708
Synthesis and evaluation of novel biodegradable hydrogels based on poly(ethylene glycol) and sebacic acid as tissue engineering scaffolds.	2008-01	18072747
A QSPR for the plasticization efficiency of polyvinylchloride plasticizers.	2008-01	17566774
Structural characterization of synthetic poly(ester amide) from sebacic acid and 4-amino-1-butanol by matrix-assisted laser desorption ionization time-of-flight/time-of-flight tandem mass spectrometry.	2008	18278818
Poly(glycerol sebacate) supports the proliferation and phenotypic protein expression of primary baboon vascular cells.	2007-12-15	17584900
Effects of insemination quantity on honey bee queen physiology.	2007-10-03	17912357
A new potentiometric ammonium electrode for biosensor construction.	2006	16893815
Carbohydrate, glycolipid, and lipid components from the photobiont (Scytonema sp.) of the lichen, Dictyomema glabratum.	2005-08-15	15963960
Application of TPX polymer membranes for the controlled release of triprolidine.	2002-01-31	11790496
In vitro fibrillogenesis of the amyloid beta 1-42 peptide: cholesterol potentiation and aspirin inhibition.	2002	12475558
Pharmacokinetics of the carmustine implant.	2002	12074689
The lock-in phase in the urotropine-sebacic acid system.	2001-08	11498619
Urinary organic acids in peroxisomal disorders: a simple screening method.	2001-07-05	11482738
A new HPLC method for the direct analysis of triglycerides of dicarboxylic acids in biological samples.	1999-11	10556649
Sebacic acid binding to human plasma albumin.	1993-02-09	8442769
Use of even-numbered carbon atom dicarboxylic salts in parenteral nutrition as fuel substrate.	1992-01-01	1738216
Inhibition of HIV-1 proteinase by non-peptide carboxylates.	1991-04-15	2018518
Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.	1991-01-02	2026685
Prenatal diagnosis of glutaric aciduria type II by direct chemical analysis of dicarboxylic acids in amniotic fluid.	1984-01	6698061
C6-C10-dicarboxylic aciduria: biochemical considerations in relation to diagnosis of beta-oxidation defects.	1982	6959231

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:48:31 GMT 2025` Edited by `admin` on `Mon Mar 31 17:48:31 GMT 2025`
Record UNII	97AN39ICTC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SEBACIC ACID

Official Name

English

NSC-19492

Preferred Name

English

DECANEDIOIC ACID

Systematic Name

English

SEBACIC ACID [MART.]

Common Name

English

FEMA NO. 4943

Code

English

Sebacic acid [WHO-DD]

Common Name

English

SEBACIC ACID [MI]

Common Name

English

1,8-OCTANEDICARBOXYLIC ACID

Systematic Name

English

Classification Tree Code System Code

Food Contact Sustance Notif, (FCN No.)

FCN NO. 78