Navenibart

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 15:44:37 GMT 2025` Edited by `admin` on `Wed Apr 02 15:44:37 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	975UQE9GY6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Immunoglobulin G1 [256-tyrosine,258-threonine,260-glutamic acid,de-C-terminal-lysine], anti-(human plasma kallikrein) (human-Mus musculus monoclonal STAR-0215 ?1-chain), disulfide with human-Mus musculus monoclonal STAR-0215 ?-chain, dimer

Preferred Name

English

Navenibart

Official Name

English

STAR-0215

Code

English

navenibart [INN]

Common Name

English

NAVENIBART [USAN]

Common Name

English

Code System Code Type Description

USAN

LM-72

Created by admin on Wed Apr 02 15:44:37 GMT 2025 , Edited by admin on Wed Apr 02 15:44:37 GMT 2025

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FDA UNII

975UQE9GY6

Created by admin on Wed Apr 02 15:44:37 GMT 2025 , Edited by admin on Wed Apr 02 15:44:37 GMT 2025

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NCI_THESAURUS

C203148

Created by admin on Wed Apr 02 15:44:37 GMT 2025 , Edited by admin on Wed Apr 02 15:44:37 GMT 2025

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INN

12991

Created by admin on Wed Apr 02 15:44:37 GMT 2025 , Edited by admin on Wed Apr 02 15:44:37 GMT 2025

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SMS_ID

300000048416

Created by admin on Wed Apr 02 15:44:37 GMT 2025 , Edited by admin on Wed Apr 02 15:44:37 GMT 2025

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CAS

2803430-16-0

Created by admin on Wed Apr 02 15:44:37 GMT 2025 , Edited by admin on Wed Apr 02 15:44:37 GMT 2025

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From	To
1_22	1_96
2_22	2_96
2_148	2_204
2_224	4_214
2_265	2_325
1_148	1_204
2_371	2_429
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_224	3_214
1_230	2_230
1_233	2_233
1_265	1_325
1_371	1_429

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_301
N	2_301

Related Record Type Details


					975UQE9GY6

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION					PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL