U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 6C6H11NO.Tc
Molecular Weight 776.95
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 1

SHOW SMILES / InChI
Structure of TECHNETIUM TC-99M SESTAMIBI

SMILES

[Tc+].COC(C)(C)C[N+]#[C-].COC(C)(C)C[N+]#[C-].COC(C)(C)C[N+]#[C-].COC(C)(C)C[N+]#[C-].COC(C)(C)C[N+]#[C-].COC(C)(C)C[N+]#[C-]

InChI

InChIKey=ZBTQTVSNLRPJHI-UHFFFAOYSA-N
InChI=1S/6C6H11NO.Tc/c6*1-6(2,8-4)5-7-3;/h6*5H2,1-2,4H3;/q;;;;;;+1

HIDE SMILES / InChI
Molecular Formula C6H11NO
Molecular Weight 113.1576
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Tc
Molecular Weight 98.0
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

1973
98
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Approved
8429
OSTEOLITE

Approved Use

Unknown

Launch Date

1977
Diagnostic
Approved
8429
DRAXIMAGE MDP-10

Approved Use

MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis.

Launch Date

1978
PubMed

PubMed

TitleDatePubMed
Future of low specific activity molybdenum-99/technetium-99m generator.
2012 Oct
Patents

Patents

20050082469
43

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:22:20 GMT 2023
Edited
by admin
on Sat Dec 16 17:22:20 GMT 2023
Record UNII
971Z4W1S09
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TECHNETIUM TC-99M SESTAMIBI
Common Name English
TECHNETIUM TC 99M SESTAMIBI [VANDF]
Common Name English
TC99M-RP-30A
Code English
TECHNETIUM TC 99M SESTAMIBI [USAN]
Common Name English
TECHNETIUM TC-99M SESTAMIBI KIT [ORANGE BOOK]
Common Name English
TECHNETIUM (99MTC) SESTAMIBI
INN  
INN  
Official Name English
TECHNETIUM TC-99M SESTAMIBI KIT
ORANGE BOOK  
Common Name English
SESTAMIBI
VANDF  
Common Name English
Technetium (99m tc) sestamibi [WHO-DD]
Common Name English
SESTAMIBI [VANDF]
Common Name English
CARDIOLITE
Common Name English
TC99M RP-30A
Code English
TECHNETIUM TC 99M SESTAMIBI
MI   USAN   VANDF  
USAN  
Official Name English
technetium (⁹⁹mTc) sestamibi [INN]
Common Name English
TECHNETIUM TC 99M SESTAMIBI [MI]
Common Name English
TECHNETIUM (99M TC) SESTAMIBI
WHO-DD  
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C2124
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
NDF-RT N0000000205
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
NDF-RT N0000177914
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
WHO-ATC V09GA01
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
Code System Code Type Description
ChEMBL
CHEMBL2110552
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
DRUG BANK
DB09161
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
DRUG CENTRAL
5124
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
MESH
D017256
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
FDA UNII
971Z4W1S09
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
USAN
Z-56
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
RXCUI
1482913
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY RxNorm
EPA CompTox
DTXSID00911248
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
EVMPD
SUB10857MIG
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
MERCK INDEX
m10509
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY Merck Index
LACTMED
Technetium Tc 99m Sestamibi
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
SMS_ID
100000091371
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
CAS
109581-73-9
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
DAILYMED
971Z4W1S09
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
WIKIPEDIA
Technetium (99mTc) sestamibi
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
INN
6243
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
NCI_THESAURUS
C1419
Created by admin on Sat Dec 16 17:22:20 GMT 2023 , Edited by admin on Sat Dec 16 17:22:20 GMT 2023
PRIMARY
Related Record Type Details
Structure of TECHNETIUM TC-99M SESTAMIBI
ACTIVE MOIETY
Structure of TECHNETIUM TC-99M
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966