CALCIUM ARSENATE

US Previously Marketed

First marketed in 1921

Details

Stereochemistry	ACHIRAL
Molecular Formula	2AsO4.3Ca
Molecular Weight	398.072
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Ca++].[Ca++].[Ca++].[O-][As]([O-])([O-])=O.[O-][As]([O-])([O-])=O

InChI

InChIKey=RMBBSOLAGVEUSI-UHFFFAOYSA-H

InChI=1S/2AsH3O4.3Ca/c2*2-1(3,4)5;;;/h2*(H3,2,3,4,5);;;/q;;3*+2/p-6

HIDE SMILES / InChI

Molecular Formula	AsO4
Molecular Weight	138.9192
Charge	-3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Ca
Molecular Weight	40.078
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://link.springer.com/chapter/10.1007/978-1-4684-6168-8_3 | https://www.nj.gov/health/eoh/rtkweb/documents/fs/0086.pdf

Ammonium dihydrogen arsenate is an inorganic compound that has been considered a potential electro-optic material and has been explored by a number of investigators for modulation purposes. Ammonium arsenate is a cancerogenic substance.

Approval Year

PubMed

Title	Date	PubMed
Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.	1994 Nov 15	7954421
Inorganic and methylated arsenic compounds induce cell death in murine macrophages via different mechanisms.	1998 Apr	9548797
Purine nucleoside phosphorylase as a cytosolic arsenate reductase.	2002 Nov	12388830
Human 3'-phosphoadenosine 5'-phosphosulfate synthetase (isoform 1, brain): kinetic properties of the adenosine triphosphate sulfurylase and adenosine 5'-phosphosulfate kinase domains.	2004 Apr 13	15065880
Regulation of cytoplasmic stress granules by apoptosis-inducing factor.	2004 Sep 1	15316071
Developmentally restricted genetic determinants of human arsenic metabolism: association between urinary methylated arsenic and CYT19 polymorphisms in children.	2005 Jun	15929903
Redox regulation of RhoA.	2006 Dec 5	17128987
Organic anion transporting polypeptide-C mediates arsenic uptake in HEK-293 cells.	2006 Jul	16479312
Glutathione-S-transferase-omega [MMA(V) reductase] knockout mice: enzyme and arsenic species concentrations in tissues after arsenate administration.	2006 Nov 1	16930657
Glutathione-dependent reduction of arsenate by glycogen phosphorylase a reaction coupled to glycogenolysis.	2007 Nov	17693425
Glutathione-dependent reduction of arsenate by glycogen phosphorylase responsiveness to endogenous and xenobiotic inhibitors.	2007 Nov	17693424
Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols.	2009 Aug	19478237
Effects of different inorganic arsenic species in Cyprinus carpio (Cyprinidae) tissues after short-time exposure: bioaccumulation, biotransformation and biological responses.	2009 Dec	19632019
Inorganic arsenic modulates the expression of selenoproteins in mouse embryonic stem cell.	2009 Jun 1	19429247
Disruption of the arsenic (+3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention of orally administered arsenate.	2009 Oct	19691357
Role of autophagy in arsenite-induced neurotoxicity: the involvement of α-synuclein.	2015 Mar 18	25639566

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:42:07 UTC 2023` Edited by `admin` on `Fri Dec 15 16:42:07 UTC 2023`
Record UNII	95OX15I8ZU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CALCIUM ARSENATE

Systematic Name

English

CALCIUM ARSENATE [MI]

Common Name

English

CALCAREA ARSENICICA

Common Name

English

Calcium arsenate [WHO-DD]

Common Name

English

ARSENIC ACID (H(SUB 3)ASO(SUB 4)) CALCIUM SALT (2:3)

Common Name

English

CALCIUM ARSENATE [HSDB]

Common Name

English

CALCAREA ARSENICICA [HPUS]

Common Name

English

ARSENIC ACID (H3ASO4), CALCIUM SALT (2:3)

Common Name

English

CALCIUM ARSENATE (CA3(ASO4)2)

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

13501