Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | 2C2H3O2.Cd |
| Molecular Weight | 230.499 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Cd++].CC([O-])=O.CC([O-])=O
InChI
InChIKey=LHQLJMJLROMYRN-UHFFFAOYSA-L
InChI=1S/2C2H4O2.Cd/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2
| Molecular Formula | C2H3O2 |
| Molecular Weight | 59.044 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Cd |
| Molecular Weight | 112.411 |
| Charge | 2 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: human serum albumin aggregation Sources: https://www.ncbi.nlm.nih.gov/pubmed/24771482 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Exposure of chick embryos to cadmium changes the extra-embryonic vascular branching pattern and alters expression of VEGF-A and VEGF-R2. | 2015-11-15 |
|
| The role of mitogen-activated protein kinase in cadmium-induced primary rat cerebral cortical neurons apoptosis via a mitochondrial apoptotic pathway. | 2015-01 |
|
| Critical cysteines in Akt1 regulate its activity and proteasomal degradation: implications for neurodegenerative diseases. | 2014-09 |
|
| Cadmium induces PC12 cells apoptosis via an extracellular signal-regulated kinase and c-Jun N-terminal kinase-mediated mitochondrial apoptotic pathway. | 2014-05 |
|
| Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals. | 2014-01 |
|
| Protective effects of quercetin on cadmium-induced cytotoxicity in primary cultures of rat proximal tubular cells. | 2013-04 |
|
| Disturbance of SHH signalling pathway during early embryogenesis in the cadmium-induced omphalocele chick model. | 2013-02 |
|
| Cadmium-induced up-regulation of aldo-keto reductase 1C3 expression in human nasal septum carcinoma RPMI-2650 cells: Involvement of reactive oxygen species and phosphatidylinositol 3-kinase/Akt. | 2011-05 |
|
| Involvement of E2F1 transcriptional activity in cadmium-induced cell-cycle arrest at G1 in human lung fibroblasts. | 2011-03 |
|
| Pre-treatment with N-acetylcysteine upregulates superoxide dismutase 2 and catalase genes in cadmium-induced oxidative stress in the chick omphalocele model. | 2011-02 |
|
| Biochemical and molecular effects of gestational and lactational coexposure to lead and cadmium on ovarian steroidogenesis are associated with oxidative stress in F1 generation rats. | 2010-12-25 |
|
| Gene expression profiling in human lung fibroblast following cadmium exposure. | 2008-03 |
|
| Effect of co-exposure to lead and cadmium on antioxidant status in rat ovarian granulose cells. | 2007-03 |
|
| The in vitro immune modulation by cadmium depends on the way of cell activation. | 2006-05-01 |
|
| A rapid and transient ROS generation by cadmium triggers apoptosis via caspase-dependent pathway in HepG2 cells and this is inhibited through N-acetylcysteine-mediated catalase upregulation. | 2006-05-01 |
|
| Integrating time-course microarray gene expression profiles with cytotoxicity for identification of biomarkers in primary rat hepatocytes exposed to cadmium. | 2006-01-01 |
|
| Role of mitogen activated protein kinases and protein kinase C in cadmium-induced apoptosis of primary epithelial lung cells. | 2005-08-01 |
|
| Effects of cadmium exposure on testis apoptosis in the marine teleost Gobius niger. | 2005-05-15 |
|
| Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway. | 2004-11-01 |
|
| Induction of orphan nuclear receptor Nur77 gene expression and its role in cadmium-induced apoptosis in lung. | 2004-08 |
|
| Identification of genes that are induced after cadmium exposure by suppression subtractive hybridization. | 2003-09-30 |
|
| Reactive oxygen species may participate in the mutagenicity and mutational spectrum of cadmium in Chinese hamster ovary-K1 cells. | 1996-12 |
|
| Nerve growth factor-stimulated calcium uptake into PC12 cells: uniqueness of the channel and evidence for phosphorylation. | 1992-04 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:08:32 GMT 2025
by
admin
on
Mon Mar 31 19:08:32 GMT 2025
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| Record UNII |
95KC50Z1L0
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| Record Status |
Validated (UNII)
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| Record Version |
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