Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C8H14FNO4 |
Molecular Weight | 207.1995 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
N[C@@H](C[C@H](CCCF)C(O)=O)C(O)=O
InChI
InChIKey=MKDNDKMECWBLOF-WDSKDSINSA-N
InChI=1S/C8H14FNO4/c9-3-1-2-5(7(11)12)4-6(10)8(13)14/h5-6H,1-4,10H2,(H,11,12)(H,13,14)/t5-,6-/m0/s1
Molecular Formula | C8H14FNO4 |
Molecular Weight | 207.1995 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Florilglutamic acid enters cells through a transport system known as xC- (cystine/glutamate antiporter) which is more abundant in cancer tissue. Florilglutamic acid (18F) is a radioactive compound for use with an imaging method known as positron
emission tomography (PET). When injected into the patient, florilglutamic acid (18F) is
more effectively taken up by the cancer cells in the liver from where it is expected to emit radiation
that can be detected in a PET scan, thereby allowing the cancer to be diagnosed. Orphan designation (EU/3/16/1632) was granted by the European Commission to Piramal Imaging GmbH, Germany, for florilglutamic acid (18F) for the diagnosis of hepatocellular carcinoma.
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 01:32:29 GMT 2023
by
admin
on
Sat Dec 16 01:32:29 GMT 2023
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Record UNII |
954ZFH0S16
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Record Status |
Validated (UNII)
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Record Version |
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-
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Common Name | English |
Classification Tree | Code System | Code | ||
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FDA ORPHAN DRUG |
517616
Created by
admin on Sat Dec 16 01:32:29 GMT 2023 , Edited by admin on Sat Dec 16 01:32:29 GMT 2023
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Code System | Code | Type | Description | ||
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1196794-42-9
Created by
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954ZFH0S16
Created by
admin on Sat Dec 16 01:32:29 GMT 2023 , Edited by admin on Sat Dec 16 01:32:29 GMT 2023
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44473414
Created by
admin on Sat Dec 16 01:32:29 GMT 2023 , Edited by admin on Sat Dec 16 01:32:29 GMT 2023
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DTXSID10152544
Created by
admin on Sat Dec 16 01:32:29 GMT 2023 , Edited by admin on Sat Dec 16 01:32:29 GMT 2023
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100000177263
Created by
admin on Sat Dec 16 01:32:29 GMT 2023 , Edited by admin on Sat Dec 16 01:32:29 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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LABELED -> NON-LABELED |
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