U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 13:44:26 GMT 2023
Edited
by admin
on Sat Dec 16 13:44:26 GMT 2023
Nucleic Acid Type OLIGONUCLEOTIDE
Nucleic Acid Subtype
Record UNII
950736UC77
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
INOTERSEN SODIUM
USAN  
USAN  
Official Name English
INOTERSEN SODIUM [ORANGE BOOK]
Common Name English
ISIS-420915 SODIUM SALT
Code English
INOTERSEN SODIUM [USAN]
Common Name English
TEGSEDI
Brand Name English
Inotersen sodium [WHO-DD]
Common Name English
ISIS-420915 SODIUM
Code English
INOTERSEN SODIUM [MI]
Common Name English
ISIS 420915 SODIUM
Code English
Classification Tree Code System Code
EU-Orphan Drug EU/3/14/1250
Created by admin on Sat Dec 16 13:44:26 GMT 2023 , Edited by admin on Sat Dec 16 13:44:26 GMT 2023
Code System Code Type Description
CAS
1432726-13-0
Created by admin on Sat Dec 16 13:44:26 GMT 2023 , Edited by admin on Sat Dec 16 13:44:26 GMT 2023
PRIMARY
EPA CompTox
DTXSID801027904
Created by admin on Sat Dec 16 13:44:26 GMT 2023 , Edited by admin on Sat Dec 16 13:44:26 GMT 2023
PRIMARY
FDA UNII
950736UC77
Created by admin on Sat Dec 16 13:44:26 GMT 2023 , Edited by admin on Sat Dec 16 13:44:26 GMT 2023
PRIMARY
RXCUI
2099290
Created by admin on Sat Dec 16 13:44:26 GMT 2023 , Edited by admin on Sat Dec 16 13:44:26 GMT 2023
PRIMARY
DAILYMED
950736UC77
Created by admin on Sat Dec 16 13:44:26 GMT 2023 , Edited by admin on Sat Dec 16 13:44:26 GMT 2023
PRIMARY
MERCK INDEX
m12102
Created by admin on Sat Dec 16 13:44:26 GMT 2023 , Edited by admin on Sat Dec 16 13:44:26 GMT 2023
PRIMARY
PUBCHEM
121493436
Created by admin on Sat Dec 16 13:44:26 GMT 2023 , Edited by admin on Sat Dec 16 13:44:26 GMT 2023
PRIMARY
USAN
CD-07
Created by admin on Sat Dec 16 13:44:26 GMT 2023 , Edited by admin on Sat Dec 16 13:44:26 GMT 2023
PRIMARY
DRUG BANK
DBSALT002811
Created by admin on Sat Dec 16 13:44:26 GMT 2023 , Edited by admin on Sat Dec 16 13:44:26 GMT 2023
PRIMARY
NCI_THESAURUS
C175090
Created by admin on Sat Dec 16 13:44:26 GMT 2023 , Edited by admin on Sat Dec 16 13:44:26 GMT 2023
PRIMARY
Sugar Site Range Site Count
Deoxyribose (DNA) 1_6-1_15 10 / 20
2-O-beta-hydroxy-ethoxy-methyl Ribose (Qiagen) 1_1-1_5;1_16-1_20 10 / 20
Linkage Site Range Site Count
Sodium Phosporothioate 1_2-1_20 19 / 19
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
NUCLEOSIDE_SUBSTITUTION [1_10] SITE_SPECIFIC 5-METHYLDEOXYCYTIDINE B200GV71QM
NUCLEOSIDE_SUBSTITUTION [1_1] [1_3] [1_4] [1_17] SITE_SPECIFIC 2'-O-(2-METHOXYETHYL)-5-METHYLURIDINE 9Q36I4D9VB
NUCLEOSIDE_SUBSTITUTION [1_2] [1_18] [1_19] [1_20] SITE_SPECIFIC 2'-O-(2-METHOXYETHYL)-5-METHYLCYTIDINE AOQ54IZZ6J