Pyrrolidine Hydrochloride

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H9N.ClH
Molecular Weight	107.582
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.C1CCNC1

InChI

InChIKey=FCLZCOCSZQNREK-UHFFFAOYSA-N

InChI=1S/C4H9N.ClH/c1-2-4-5-3-1;/h5H,1-4H2;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C4H9N
Molecular Weight	71.121
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 4: synthesis of N-1 acidic functionality affording analogues with enhanced antiviral activity against HIV.	2002-10-21	12270193
Dopamine D3 receptor ligands with antagonist properties.	2002-10-04	12362359
Generation and cycloaddition of polymer-supported azomethine ylide via a 1,2-silatropic shift of alpha-silylimines: traceless synthesis of pyrrolidine derivatives.	2002-10-03	12323055
Diastereoisomeric singly bridged cyclophosphazene-macrocyclic compounds.	2002-09-23	12230399
Photomodulation of the chiroptical properties of new chiral methacrylic polymers with side chain azobenzene moieties.	2002-09-16	12298015
A novel metal iodide promoted three-component synthesis of substituted pyrrolidines.	2002-09-05	12201738
Site of protonation of nicotine and nornicotine in the gas phase: pyridine or pyrrolidine nitrogen?	2002-09-04	12197757
Isolation and structure elucidation of two new alkaloids, pandamarilactonine-C and -D, from Pandanus amaryllifolius and revision of relative stereochemistry of pandamarilactonine-A and -B by total synthesis.	2002-09	12237561
Synthesis and evaluation of Glypsi(PO(2)R-N)Pro-containing pseudopeptides as novel inhibitors of the human cyclophilin hCyp-18.	2002-08-29	12190314
Quantitative model studies on the efficiency of precursors in the formation of cooling-active 1-pyrrolidinyl-2-cyclopenten-1-ones and bitter-tasting cyclopenta-[b]azepin-8(1H)-ones.	2002-08-28	12188623
Total synthesis of batzelladine D.	2002-08-22	12182589
Polyhydroxy alkaloids: chromatographic analysis.	2002-08-16	12219930
A novel pyrrolidinyl PNA showing high sequence specificity and preferential binding to DNA over RNA.	2002-08-14	12166999
Content of biogenic amines in a Chardonnay wine obtained through spontaneous and inoculated fermentations.	2002-08-14	12166978
Simultaneous quantitative assay of six HIV protease inhibitors, one metabolite, and two non-nucleoside reverse transcriptase inhibitors in human plasma by isocratic reversed-phase liquid chromatography.	2002-08	12142642
Sebastianines A and B, novel biologically active pyridoacridine alkaloids from the Brazilian ascidian Cystodytes dellechiajei.	2002-07-26	12126446
One-pot synthesis of 3,4-disubstituted 1H-pyrroles from 2-tropanones.	2002-07-12	12098329
Conformational preferences of substituted prolines in the collagen triple helix.	2002-07-05	11979516
Understanding the role of stereoelectronic effects in determining collagen stability. 2. A quantum mechanical/molecular mechanical study of (Proline-Proline-Glycine)(n) polypeptides.	2002-07-03	12083941
Synthesis of new 1-(but-2-ynyl)pyrazoles: containing a pyrrolidine or diethylamine moiety and their muscarinic properties.	2002-07	12207284
Anaerobic degradation of pyrrolidine and piperidine coupled with nitrate reduction.	2002-07	12146621
(R)-N-[11C]methyl-3-pyrrolidyl benzilate, a high-affinity reversible radioligand for PET studies of the muscarinic acetylcholine receptor.	2002-07	12112411
1-Substituted derivatives of 2-aryl-5-oxopyrrolidine-2-carboxylic acid.	2002-07	12094058
1-Substituted derivatives of 2-phenylpyrrolidine-2-carboxamide.	2002-07	12094054
Quantitative structure-activity relationships for a series of symmetrical bisquaternary anticancer compounds.	2002-07	11983519
4-Phenylbutanoyl-2(S)-acylpyrrolidines and 4-phenylbutanoyl-L-prolyl-2(S)-acylpyrrolidines as prolyl oligopeptidase inhibitors.	2002-07	11983517
Design, synthesis, and evaluation of new chemosensitizers in multi-drug-resistant Plasmodium falciparum.	2002-06-20	12061877
Antioxidative properties of pyrrolidinium and piperidinium salts.	2002-06-18	12064738
Studies on the metabolism and toxicological detection of the new designer drug 4'-methyl-alpha-pyrrolidinopropiophenone in urine using gas chromatography-mass spectrometry.	2002-06-15	12015267
Unique ionic iodine atom transfer cyclization: a new route to iodomethylated pyrrolidine derivatives from gamma-iodoolefin and chloramine-T.	2002-06-13	12049527
New enamine derivatives of lapachol and biological activity.	2002-06	12098751
Isolation and characterization of a novel Pseudomonas sp., strain YG1, capable of degrading pyrrolidine under denitrifying conditions.	2002-05-21	12052559
Characterization of a novel inhibitor of cytosolic phospholipase A2alpha, pyrrophenone.	2002-05-01	11964173
Studies on novel peptidomimetics having bi-directional dispositions of hydroxylated D-Pro-Gly motifs anchored on a C(2)-symmetric iminosugar-based foundation.	2002-04-05	11925214
Aqueous aldol catalysis by a nicotine metabolite.	2002-04-03	11916401
Speciation of lead in environmental waters by preconcentration on a new fullerene derivative.	2002-04-01	12033239
Synthesis of aza polycyclic compounds derived from pyrrolidine, indolizidine, and indole via intramolecular Diels-Alder cycloadditions of neutral 2-azadienes.	2002-03-22	11895415
Collagen stability: insights from NMR spectroscopic and hybrid density functional computational investigations of the effect of electronegative substituents on prolyl ring conformations.	2002-03-20	11890798
Synthesis, structure, and preparative transamination of tetrazinc carbamato complexes having the basic zinc carboxylate structure.	2002-03-11	11874346
Synthesis, antiarrhythmic, and antihypertensive effects of novel 1-substituted pyrrolidin-2-one and pyrrolidine derivatives with adrenolytic activity.	2002-03	11900863
Antifungal amides from Piper arboreum and Piper tuberculatum.	2002-03	11853747
Hydroxylated pyrrolidines. Enantiospecific synthesis of all-cis 2,3,4,5-substituted pyrrolidine derivatives from serine.	2002-02-22	11846680
An unexpected [1,5]-h shift in the synthesis of nitroanilines.	2002-02-07	11820899
Quantum mechanical study of the conformational behavior of proline and 4R-hydroxyproline dipeptide analogues in vacuum and in aqueous solution.	2002-02	11908497
6-Propylamino-2,6-propylepimino-2,4,4,8,8-pentakis(pyrrolidin-1-yl)-1,3,5,7,2lambda5,4lambda5,6lambda5,8lambda5-tetraazatetraphosphorocine.	2002-02	11828115
Syn- and anticlinal isomers of 2a'-acetoxy-1,7'-diacetyl-7',7a'-dihydro-2-oxospiro[1H-indole-3(2H),2'(2a'H)-oxeto[3,2-b]indole].	2002-02	11828108
Total synthesis of spirotryprostatin B via asymmetric nitroolefination.	2002-01-24	11796062
Molecular orbital calculations and nicotine metabolism: a rationale for experimentally observed metabolite ratios.	2002	12222752
Evidence that RDX biodegradation by Rhodococcus strain DN22 is plasmid-borne and involves a cytochrome p-450.	2002	12174045
Direct chemotactic effect of bradykinin and related peptides-significance of amino- and carboxyterminal character of oligopeptides in chemotaxis of tetrahymena pyriformis.	2002	11779221

Patents

Substance Class	Chemical Created by `admin` on `Tue Apr 01 19:51:16 GMT 2025` Edited by `admin` on `Tue Apr 01 19:51:16 GMT 2025`
Record UNII	94N92BZG67
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-203096

Preferred Name

English

Pyrrolidine Hydrochloride

Systematic Name

English

Pyrrolidine, hydrochloride (1:1)

Systematic Name

English

PYRROLIDINE, HYDROCHLORIDE

Systematic Name

English

Code System Code Type Description

FDA UNII

94N92BZG67