Pyrrolidine Hydrochloride

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H9N.ClH
Molecular Weight	107.582
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.C1CCNC1

InChI

InChIKey=FCLZCOCSZQNREK-UHFFFAOYSA-N

InChI=1S/C4H9N.ClH/c1-2-4-5-3-1;/h5H,1-4H2;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C4H9N
Molecular Weight	71.121
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Ab-initio molecular geometry and normal coordinate analysis of pyrrolidine molecule.	2001 Nov	11765792
Molecular orbital calculations and nicotine metabolism: a rationale for experimentally observed metabolite ratios.	2002	12222752
Evidence that RDX biodegradation by Rhodococcus strain DN22 is plasmid-borne and involves a cytochrome p-450.	2002	12174045
Direct chemotactic effect of bradykinin and related peptides-significance of amino- and carboxyterminal character of oligopeptides in chemotaxis of tetrahymena pyriformis.	2002	11779221
Speciation of lead in environmental waters by preconcentration on a new fullerene derivative.	2002 Apr 1	12033239
Aqueous aldol catalysis by a nicotine metabolite.	2002 Apr 3	11916401
Studies on novel peptidomimetics having bi-directional dispositions of hydroxylated D-Pro-Gly motifs anchored on a C(2)-symmetric iminosugar-based foundation.	2002 Apr 5	11925214
Simultaneous quantitative assay of six HIV protease inhibitors, one metabolite, and two non-nucleoside reverse transcriptase inhibitors in human plasma by isocratic reversed-phase liquid chromatography.	2002 Aug	12142642
A novel pyrrolidinyl PNA showing high sequence specificity and preferential binding to DNA over RNA.	2002 Aug 14	12166999
Content of biogenic amines in a Chardonnay wine obtained through spontaneous and inoculated fermentations.	2002 Aug 14	12166978
Polyhydroxy alkaloids: chromatographic analysis.	2002 Aug 16	12219930
Total synthesis of batzelladine D.	2002 Aug 22	12182589
Quantitative model studies on the efficiency of precursors in the formation of cooling-active 1-pyrrolidinyl-2-cyclopenten-1-ones and bitter-tasting cyclopenta-[b]azepin-8(1H)-ones.	2002 Aug 28	12188623
Quantum mechanical study of the conformational behavior of proline and 4R-hydroxyproline dipeptide analogues in vacuum and in aqueous solution.	2002 Feb	11908497
6-Propylamino-2,6-propylepimino-2,4,4,8,8-pentakis(pyrrolidin-1-yl)-1,3,5,7,2lambda5,4lambda5,6lambda5,8lambda5-tetraazatetraphosphorocine.	2002 Feb	11828115
Syn- and anticlinal isomers of 2a'-acetoxy-1,7'-diacetyl-7',7a'-dihydro-2-oxospiro[1H-indole-3(2H),2'(2a'H)-oxeto[3,2-b]indole].	2002 Feb	11828108
Hydroxylated pyrrolidines. Enantiospecific synthesis of all-cis 2,3,4,5-substituted pyrrolidine derivatives from serine.	2002 Feb 22	11846680
An unexpected [1,5]-h shift in the synthesis of nitroanilines.	2002 Feb 7	11820899
Novel cyclic sugar imines: carbohydrate mimics and easily elaborated scaffolds for aza-sugars.	2002 Jan 10	11772101
IL-6 secretion by human pancreatic periacinar myofibroblasts in response to inflammatory mediators.	2002 Jan 15	11777983
Total synthesis of spirotryprostatin B via asymmetric nitroolefination.	2002 Jan 24	11796062
Anaerobic degradation of pyrrolidine and piperidine coupled with nitrate reduction.	2002 Jul	12146621
(R)-N-[11C]methyl-3-pyrrolidyl benzilate, a high-affinity reversible radioligand for PET studies of the muscarinic acetylcholine receptor.	2002 Jul	12112411
1-Substituted derivatives of 2-aryl-5-oxopyrrolidine-2-carboxylic acid.	2002 Jul	12094058
1-Substituted derivatives of 2-phenylpyrrolidine-2-carboxamide.	2002 Jul	12094054
Quantitative structure-activity relationships for a series of symmetrical bisquaternary anticancer compounds.	2002 Jul	11983519
4-Phenylbutanoyl-2(S)-acylpyrrolidines and 4-phenylbutanoyl-L-prolyl-2(S)-acylpyrrolidines as prolyl oligopeptidase inhibitors.	2002 Jul	11983517
One-pot synthesis of 3,4-disubstituted 1H-pyrroles from 2-tropanones.	2002 Jul 12	12098329
Sebastianines A and B, novel biologically active pyridoacridine alkaloids from the Brazilian ascidian Cystodytes dellechiajei.	2002 Jul 26	12126446
Understanding the role of stereoelectronic effects in determining collagen stability. 2. A quantum mechanical/molecular mechanical study of (Proline-Proline-Glycine)(n) polypeptides.	2002 Jul 3	12083941
Conformational preferences of substituted prolines in the collagen triple helix.	2002 Jul 5	11979516
New enamine derivatives of lapachol and biological activity.	2002 Jun	12098751
Unique ionic iodine atom transfer cyclization: a new route to iodomethylated pyrrolidine derivatives from gamma-iodoolefin and chloramine-T.	2002 Jun 13	12049527
Studies on the metabolism and toxicological detection of the new designer drug 4'-methyl-alpha-pyrrolidinopropiophenone in urine using gas chromatography-mass spectrometry.	2002 Jun 15	12015267
Design, synthesis, and evaluation of new chemosensitizers in multi-drug-resistant Plasmodium falciparum.	2002 Jun 20	12061877
Synthesis, antiarrhythmic, and antihypertensive effects of novel 1-substituted pyrrolidin-2-one and pyrrolidine derivatives with adrenolytic activity.	2002 Mar	11900863
Antifungal amides from Piper arboreum and Piper tuberculatum.	2002 Mar	11853747
Synthesis, structure, and preparative transamination of tetrazinc carbamato complexes having the basic zinc carboxylate structure.	2002 Mar 11	11874346
Collagen stability: insights from NMR spectroscopic and hybrid density functional computational investigations of the effect of electronegative substituents on prolyl ring conformations.	2002 Mar 20	11890798
Synthesis of aza polycyclic compounds derived from pyrrolidine, indolizidine, and indole via intramolecular Diels-Alder cycloadditions of neutral 2-azadienes.	2002 Mar 22	11895415
Antioxidative properties of pyrrolidinium and piperidinium salts.	2002 Mar-Apr	12064738
Characterization of a novel inhibitor of cytosolic phospholipase A2alpha, pyrrophenone.	2002 May 1	11964173
Isolation and characterization of a novel Pseudomonas sp., strain YG1, capable of degrading pyrrolidine under denitrifying conditions.	2002 May 21	12052559
1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 4: synthesis of N-1 acidic functionality affording analogues with enhanced antiviral activity against HIV.	2002 Oct 21	12270193
Generation and cycloaddition of polymer-supported azomethine ylide via a 1,2-silatropic shift of alpha-silylimines: traceless synthesis of pyrrolidine derivatives.	2002 Oct 3	12323055
Dopamine D3 receptor ligands with antagonist properties.	2002 Oct 4	12362359
Isolation and structure elucidation of two new alkaloids, pandamarilactonine-C and -D, from Pandanus amaryllifolius and revision of relative stereochemistry of pandamarilactonine-A and -B by total synthesis.	2002 Sep	12237561
Photomodulation of the chiroptical properties of new chiral methacrylic polymers with side chain azobenzene moieties.	2002 Sep 16	12298015
Diastereoisomeric singly bridged cyclophosphazene-macrocyclic compounds.	2002 Sep 23	12230399
Site of protonation of nicotine and nornicotine in the gas phase: pyridine or pyrrolidine nitrogen?	2002 Sep 4	12197757

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 12:50:54 GMT 2023` Edited by `admin` on `Sat Dec 16 12:50:54 GMT 2023`
Record UNII	94N92BZG67
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Pyrrolidine Hydrochloride

Systematic Name

English

Pyrrolidine, hydrochloride (1:1)

Systematic Name

English

PYRROLIDINE, HYDROCHLORIDE

Systematic Name

English

NSC-203096

Code

English

Code System Code Type Description

FDA UNII

94N92BZG67