Ultevursen

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 14:45:59 UTC 2023` Edited by `admin` on `Sat Dec 16 14:45:59 UTC 2023`
Nucleic Acid Type	OLIGONUCLEOTIDE
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	94AC8YWE3I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Ultevursen

Official Name

English

ultevursen [INN]

Common Name

English

RNA, (P-thio)[2′-O-(2-methoxyethyl)](A-G-m5C-m5U-m5U-m5C-G-G-A-G-A-A-A-m5U-m5U-m5U-A-A-A-m5U-m5C)

Common Name

English

all-P-ambo-2'-O-(2-methoxyethyl)-P-thioadenylyl-(3'→5')-2'-O-(2-methoxyethyl)-P-thioguanylyl-(3'→5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3'→5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiouridylyl-(3'→5')-2'-O-(2-methoxyethyl)-5-methyl-P-thi

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C190320

Created by admin on Sat Dec 16 14:45:59 UTC 2023 , Edited by admin on Sat Dec 16 14:45:59 UTC 2023

PRIMARY

CAS

2642382-41-8

Created by admin on Sat Dec 16 14:45:59 UTC 2023 , Edited by admin on Sat Dec 16 14:45:59 UTC 2023

PRIMARY

FDA UNII

94AC8YWE3I

Created by admin on Sat Dec 16 14:45:59 UTC 2023 , Edited by admin on Sat Dec 16 14:45:59 UTC 2023

PRIMARY

INN

12307

Created by admin on Sat Dec 16 14:45:59 UTC 2023 , Edited by admin on Sat Dec 16 14:45:59 UTC 2023

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methoxyethyl ribose	1_1-1_21	21 / 21

Linkage	Site Range	Site Count
Phosporothioate	1_1-1_20	20 / 20

Related Record Type Details


					94AC8YWE3I

Ultevursen

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOSIDE BASE SUBSTITUTION	[1_4] [1_5] [1_14] [1_15] [1_16] [1_20]	SITE_SPECIFIC			THYMINE RIBOSIDE	ZS1409014A
NUCLEOSIDE BASE SUBSTITUTION	[1_3] [1_6] [1_21]	SITE_SPECIFIC			5-METHYLCYTIDINE	TL9PB228DC