Details
| Stereochemistry | EPIMERIC |
| Molecular Formula | C20H31N3O6S |
| Molecular Weight | 441.542 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 4 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2\N=C\N3CCCCCC3)C(=O)OC(C)OC(=O)OCC
InChI
InChIKey=XHKFBADIZIDYBU-MLFVOLAISA-N
InChI=1S/C20H31N3O6S/c1-5-27-19(26)29-13(2)28-18(25)15-20(3,4)30-17-14(16(24)23(15)17)21-12-22-10-8-6-7-9-11-22/h12-15,17H,5-11H2,1-4H3/b21-12+/t13?,14-,15+,17-/m1/s1
| Molecular Formula | C20H31N3O6S |
| Molecular Weight | 441.542 |
| Charge | 0 |
| Count |
|
| Stereochemistry | EPIMERIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 4 |
| E/Z Centers | 1 |
| Optical Activity | UNSPECIFIED |
Bacmecillinam is the orally active 1’-ethoxycarbonyloxyethyl ester of macillinam. It is rapidly absorbed and hydrolyzed, liberating the antibacterially active drug mecillinam. Protective effects of bacmecillinam was tested in experimental mouse intraperitoneal infection model. Drug demonstrated the potent protective effects against E. coli GN 2411-5, E. coli 2848, K. pneumoniae 8045, E. cloacae F-1510 and P. mirabilis F-783 infection.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 17:37:44 GMT 2023
by
admin
on
Sat Dec 16 17:37:44 GMT 2023
|
| Record UNII |
942B99D5UK
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C1500
Created by
admin on Sat Dec 16 17:37:44 GMT 2023 , Edited by admin on Sat Dec 16 17:37:44 GMT 2023
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| Code System | Code | Type | Description | ||
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SUB05668MIG
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100000086088
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C021145
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942B99D5UK
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DTXSID801023645
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50846-45-2
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C72619
Created by
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CHEMBL2106658
Created by
admin on Sat Dec 16 17:37:44 GMT 2023 , Edited by admin on Sat Dec 16 17:37:44 GMT 2023
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4245
Created by
admin on Sat Dec 16 17:37:44 GMT 2023 , Edited by admin on Sat Dec 16 17:37:44 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
