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Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 19:02:09 GMT 2023
Edited
by admin
on Sat Dec 16 19:02:09 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
93NRF4S9HR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Tobemstomig
INN  
Official Name English
RO-7247669
Code English
RO 7247669 [WHO-DD]
Common Name English
tobemstomig [INN]
Common Name English
PD1-LAG3 BSAB (RO-7247669)
Common Name English
RO7247669
Code English
Immunoglobulin G1 [151-glutamic acid,217-glutamic acid,236-alanine,237-alanine,331-glycine,351-cysteine,368-serine,370-alanine,409-valine], anti-(human lymphocyte activation gene-3 protein) (human-Oryctolagus cuniculus monoclonal LAG3-0414 γ1-chain), di
Common Name English
immunoglobulin G1-kappa with crossed domains, anti-[Homo sapiens PDCD1 (programmed cell death 1, PD1, PD-1, CD279)] and anti-[Homo sapiens LAG3 (lymphocyte activating 3, lymphocyte-activation 3, CD223)], humanized monoclonal antibody, bispecific
Common Name English
PD1/LAG3 (RO-7247669)
Common Name English
PD1-LAG3 (RO-7247669)
Common Name English
Anti-PD1/Anti-LAG3 Bispecific Antibody RO7247669
Common Name English
Code System Code Type Description
NCI_THESAURUS
C173539
Created by admin on Sat Dec 16 19:02:10 GMT 2023 , Edited by admin on Sat Dec 16 19:02:10 GMT 2023
PRIMARY
FDA UNII
93NRF4S9HR
Created by admin on Sat Dec 16 19:02:10 GMT 2023 , Edited by admin on Sat Dec 16 19:02:10 GMT 2023
PRIMARY
INN
12318
Created by admin on Sat Dec 16 19:02:10 GMT 2023 , Edited by admin on Sat Dec 16 19:02:10 GMT 2023
PRIMARY
CAS
2648839-43-2
Created by admin on Sat Dec 16 19:02:10 GMT 2023 , Edited by admin on Sat Dec 16 19:02:10 GMT 2023
PRIMARY
CAS
2640186-09-8
Created by admin on Sat Dec 16 19:02:10 GMT 2023 , Edited by admin on Sat Dec 16 19:02:10 GMT 2023
NO STRUCTURE GIVEN
From To
4_134 4_194
4_23 4_88
3_147 3_207
3_22 3_96
2_363 2_421
2_257 2_317
2_216 3_227
2_140 2_196
2_23 2_92
1_353 2_350
1_371 1_429
1_265 1_325
1_233 2_225
1_230 2_222
1_224 4_214
1_148 1_204
1_22 1_96
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_301
N 2_293
Related Record Type Details
INTERFERON GAMMA
TARGET->ACTIVATOR OF EXPRESSION
LYMPHOCYTE ACTIVATION GENE 3 PROTEIN
TARGET->LIGAND
GRANZYME B
TARGET->ACTIVATOR OF EXPRESSION
PROGRAMMED CELL DEATH PROTEIN 1
TARGET->LIGAND
Related Record Type Details
Tobemstomig
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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