DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 20:14:40 GMT 2025` Edited by `admin` on `Tue Apr 01 20:14:40 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	93EHW9XVKO
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DUAL SPECIFICITY YAK1-RELATED KINASE

Preferred Name

English

DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A

Common Name

English

DYRK1A

Common Name

English

HMNB

Common Name

English

HP86

Common Name

English

MNBH

Common Name

English

PROTEIN KINASE MINIBRAIN HOMOLOG

Common Name

English

MNB

Common Name

English

DYRK

Common Name

English

Code System Code Type Description

PHAROS

Q13627

Created by admin on Tue Apr 01 20:14:40 GMT 2025 , Edited by admin on Tue Apr 01 20:14:40 GMT 2025

PRIMARY

UNIPROT

Q13627

Created by admin on Tue Apr 01 20:14:40 GMT 2025 , Edited by admin on Tue Apr 01 20:14:40 GMT 2025

PRIMARY

FDA UNII

93EHW9XVKO

Created by admin on Tue Apr 01 20:14:40 GMT 2025 , Edited by admin on Tue Apr 01 20:14:40 GMT 2025

PRIMARY

Related Record Type Details


					F5A38P48PV

5-(6-benzothiazolylmethylene)-3,5-dihydro-2-[[(1S)-1-(methoxymethyl)-3-methylbutyl]amino]-4H-Imidazol-4-one, (5Z)-

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					97LG4X5P2E

NNI-351

INHIBITOR -> TARGET

Amount:

Structural Modifications

Modification Type	Location Site	Residue Modified	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_402]	T	THREONINE PHOSPHATE	3L4WX7B1EI
AMINO ACID SUBSTITUTION	[1_111] [1_140] [1_145] [1_159] [1_177] [1_219] [1_319] [1_321] [1_449]	Y	TYROSINE O-PHOSPHATE	2R86C98KDX
AMINO ACID SUBSTITUTION	[1_14] [1_310] [1_529] [1_538] [1_748] [1_758]	S	DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL