1,2-ETHANEDITHIOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H6S2
Molecular Weight	94.199
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

SCCS

InChI

InChIKey=VYMPLPIFKRHAAC-UHFFFAOYSA-N

InChI=1S/C2H6S2/c3-1-2-4/h3-4H,1-2H2

HIDE SMILES / InChI

Molecular Formula	C2H6S2
Molecular Weight	94.199
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Dithiothreitol causes HIV-1 integrase dimer dissociation while agents interacting with the integrase dimer interface promote dimer formation.	2011-03-15	21222490
Analgesic effect of highly reversible ω-conotoxin FVIA on N type Ca2+ channels.	2010-12-21	21172037
Overtone spectra of 2-mercaptoethanol and 1,2-ethanedithiol.	2010-12-09	21067132
Controlled plasmon resonance properties of hollow gold nanosphere aggregates.	2010-11-10	20961113
Design of potent inhibitors of human RAD51 recombinase based on BRC motifs of BRCA2 protein: modeling and experimental validation of a chimera peptide.	2010-08-12	20684611
Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A.	2010-06-30	20614028
Oligomerization of 1,2-ethanedithiol: an expedient approach to oligothiaethylenethioglycols.	2010-06-01	20411538
Gain of a 500-fold sensitivity on an intravital MR contrast agent based on an endohedral gadolinium-cluster-fullerene-conjugate: a new chance in cancer diagnostics.	2010-05-28	20567614
Dithiodiolate ligands: group 4 complexes and application in lactide polymerization.	2010-05-03	20356103
Attenuation of Pseudomonas aeruginosa virulence factors and biofilms by co-encapsulation of bismuth-ethanedithiol with tobramycin in liposomes.	2010-04	20159770
Critical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs.	2010-01-13	20084172
Identification of myotropic neuropeptides from the brain and corpus cardiacum-corpus allatum complex of the beetle, Zophobas atratus.	2010	21067424
Disruption of occludin function in polarized epithelial cells activates the extrinsic pathway of apoptosis leading to cell extrusion without loss of transepithelial resistance.	2009-12-09	20003227
Bis(dimethyl sulfoxide-κO)bis-(mercapto-acetato-κO,S)tin(IV).	2009-10-28	21578179
Structure/processing relationships of highly ordered lead salt nanocrystal superlattices.	2009-10-27	19728701
Novel gemini pyridinium surfactants: synthesis and study of their surface activity, DNA binding, and cytotoxicity.	2009-10-06	19788223
Indium complexes supported by 1,omega-dithiaalkanediyl-bridged bis(phenolato) ligands: synthesis, structure, and controlled ring-opening polymerization of L-lactide.	2009-06-15	19425567
Bismuth-thiol incorporation enhances biological activities of liposomal tobramycin against bacterial biofilm and quorum sensing molecules production by Pseudomonas aeruginosa.	2009-05-21	19429299
{μ-[2-(Dimethyl-amino)phen-yl](2-fluoro-phen-yl)methano-lato}penta-methyl-dialuminum(III).	2009-04-25	21583805
Treatment of glioblastoma multiforme cells with temozolomide-BioShuttle ligated by the inverse Diels-Alder ligation chemistry.	2009-02-06	19920915
A peptide targeted contrast agent specific to fibrin-fibronectin complexes for cancer molecular imaging with MRI.	2008-12	19053180
Spectroscopic characterization of extracellular polymeric substances from Escherichia coli and Serratia marcescens: suppression using sub-inhibitory concentrations of bismuth thiols.	2008-11	18937399
Determining the internal quantum efficiency of PbSe nanocrystal solar cells with the aid of an optical model.	2008-11	18823149
Total syntheses of (+)- and (-)-peribysin E.	2008-10-15	18783227
TMZ-BioShuttle--a reformulated temozolomide.	2008-09-15	18797509
Oligomerization of indole derivatives with incorporation of thiols.	2008-08-26	18794789
Use of thiols as protecting ligands in reflective surface films of silver nanoparticles.	2008-08	19049148
Synthesis, screening, and sequencing of cysteine-rich one-bead one-compound peptide libraries.	2008-07-29	18656989
Liposomal bismuth-ethanedithiol formulation enhances antimicrobial activity of tobramycin.	2008-06-24	18448284
Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans.	2008-06-11	18545691
The activity of HDAC8 depends on local and distal sequences of its peptide substrates.	2008-06-10	18470998
An improved synthesis of arsenic-biotin conjugates.	2008-05-15	18396406
Real-time visualization of HIV-1 GAG trafficking in infected macrophages.	2008-03-07	18369466
Structural, optical, and electrical properties of self-assembled films of PbSe nanocrystals treated with 1,2-ethanedithiol.	2008-02	19206627
A new, stereoselective, ring-forming reaction of 1,2-ethanedithiol with N-acylated indoles.	2007-11-09	17941672
Dynamic surface activity of a fully synthetic phospholipase-resistant lipid/peptide lung surfactant.	2007-10-17	17940603
Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides.	2007-10-01	17908326
Global analysis of posttranslational protein arginylation.	2007-10	17896865
Identification of an orthogonal peptide binding motif for biarsenical multiuse affinity probes.	2007-06-16	17569496
Quartz crystal microbalance biosensor for recombinant human interferon-beta detection based on antisense peptide approach.	2007-05-02	17416227
One-step synthesis of heterocyclic privileged medicinal scaffolds by a multicomponent reaction of malononitrile with aldehydes and thiols.	2007-04-27	17408286
Transition metal complexes of quinolino[3,2-b]benzodiazepine and quinolino[3,2-b]benzoxazepine: synthesis, characterization, and antimicrobial studies.	2007	18273383
Accumulation of FlAsH/Lumio Green in active mitochondria can be reversed by beta-mercaptoethanol for specific staining of tetracysteine-tagged proteins.	2006-06	16395611
Acetalization and thioacetalization of cabonyl compounds: a case study based on global and local electrophilicity descriptors.	2006-04-30	16526037
Role of vicinal protein thiols in radiation and cytotoxic responses.	2006-03	16494519
Dithiolate complexes of manganese and rhenium: X-ray structure and properties of an unusual mixed valence cluster Mn3(CO)6(mu-eta2-SCH2CH2CH2S)3.	2005-12-26	16363859
Interaction of Ag(I), Hg(II), and Cu(II) with 1,2-ethanedithiol immobilized on chitosan: thermochemical data from isothermal calorimetry.	2005-09-01	16009215
Studies of C-S bond cleavage reactions of Re(V) dithiolates: synthesis, reactivity, and mechanism.	2005-07-27	16028958
Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein.	2005-07-18	16026621
Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen.	2005	16207332

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:47:22 GMT 2025` Edited by `admin` on `Mon Mar 31 18:47:22 GMT 2025`
Record UNII	92T634FLAR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-60481

Preferred Name

English

1,2-ETHANEDITHIOL

Systematic Name

English

1,2-ETHANEDITHIOL [FHFI]

Common Name

English

ETHYLENE MERCAPTAN

Systematic Name

English

ETHANEDITHIOL, 1,2-

Systematic Name

English

DITHIOETHYLENE GLYCOL

Common Name

English

ETHYLENE DIMERCAPTAN

Systematic Name

English

1,2-DIMERCAPTOETHANE

Systematic Name

English

FEMA NO. 3484

Code

English

1,2-DITHIOLETHANE

Common Name

English

2-MERCAPTOETHANETHIOL

Systematic Name

English

ETHYLENE GLYCOL, DITHIO-

Common Name

English

S-ETHYLENE DIMERCAPTAN

Common Name

English

ETHYLENE DITHIOGLYCOL

Common Name

English

ETHYLENEDITHIOL

Common Name

English

DITHIOGLYCOL

Common Name

English

1,2-ETHANEDITHIOL [MI]

Common Name

English

1,2-ETHYLENEDITHIOL

Common Name

English

1,2-ETHANEDITHIOL [HSDB]

Common Name

English

Classification Tree Code System Code

JECFA EVALUATION

1,2-ETHANEDITHIOL