SODIUM PHENARSONE SULFOXYLATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H8AsNO6S.2Na
Molecular Weight	355.108
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SODIUM PHENARSONE SULFOXYLATE

Structure Search

SMILES

[Na+].[Na+].OC1=CC=C(C=C1NCS([O-])=O)[As](O)([O-])=O

InChI

InChIKey=DXOVFKCXTQMPEM-UHFFFAOYSA-L

InChI=1S/C7H10AsNO6S.2Na/c10-7-2-1-5(8(11,12)13)3-6(7)9-4-16(14)15;;/h1-3,9-10H,4H2,(H,14,15)(H2,11,12,13);;/q;2*+1/p-2

HIDE SMILES / InChI

Molecular Formula	C7H8AsNO6S
Molecular Weight	309.128
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.98976928
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/20323806 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 958, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | https://www.ncbi.nlm.nih.gov/pubmed/18868767

Phenarsone sulfoxylate (Aldarsone), a pentavalent arsenical, is a condensation product of 3-amino-4 hydroxylphenylarsonic acid with sodium formaldehyde sulfoxylate. It is an antiamoebic agent. Aldarsone has a spirochetal power superior to that of tryparsamide. Aldarsone may be used in conjunction with artificial fever therapy and penicillin therapy to improve the results in symptomatic syphilis of the central nervous system (neurosyphilis).

Approval Year

PubMed

Title	Date	PubMed
Aldarsone therapy in the treatment of general paresis.	1948-08	18888497
Aldarsone and bismuth combined in the treatment of neurosyphilis; report of 100 cases.	1948-07	18868767
Aldarsone and neurosyphilis.	1947-09	20260227
The use of aldarsone in the treatment of neurosyphilis.	1946-06	20983623
ALDARSONE IN NEURO-SYPHILIS.	1946-06	20323806

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:33:53 GMT 2025` Edited by `admin` on `Mon Mar 31 17:33:53 GMT 2025`
Record UNII	9260H9QVC4
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SODIUM PHENARSONE SULFOXYLATE

Common Name

English

ALDARSONE

Preferred Name

English

METHANESULFINIC ACID, 1-((5-ARSONOYL-2-HYDROXYPHENYL)AMINO)-, SODIUM SALT (1:2)

Common Name

English

NSC-31038

Code

English

PHENARSONE SULFOXYLATE, DISODIUM SALT

Common Name

English

4-HYDROXY-M-ARSANILIC ACID, COMPOUND WITH SODIUM FORMALDEHYDESULFOXYLATE

Common Name

English

Code System Code Type Description

EVMPD

SUB09751MIG