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Details

Stereochemistry ACHIRAL
Molecular Formula C2H8N2.2ClH
Molecular Weight 133.02
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ETHYLENEDIAMINE DIHYDROCHLORIDE

SMILES

Cl.Cl.NCCN

InChI

InChIKey=OHHBFEVZJLBKEH-UHFFFAOYSA-N
InChI=1S/C2H8N2.2ClH/c3-1-2-4;;/h1-4H2;2*1H

HIDE SMILES / InChI

Molecular Formula C2H8N2
Molecular Weight 60.0983
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Ethylenediamine is a strongly basic amine useful as a building block in chemical synthesis. It is used as a solvent to dissolve proteins such as albumins, casein and in medicine to stabilize aminophylline when used in injections. Ethylenediamine is used in manufacture of chelating agents (EDTA), epoxy curing agents, dimethylolethylene-urea resins, emulsifying agents, textile lubricants, antifreeze inhibitor. It is also involved in the manufacture of many industrial chemicals and forms derivatives with carboxylic acids, nitriles, alcohols, alkylating agents, carbon disulfide, aldehydes and ketones. It is a basic building block to prepare heterocyclic compound such as imidazolidines.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Ph(2)Bi-(Ge(9))-BiPh(2)](2-): a deltahedral Zintl ion functionalized by exo-bonded ligands.
2002-03-20
Role of magnesium in nucleotide exchange on the small G protein rac investigated using novel fluorescent Guanine nucleotide analogues.
2002-03-19
Designed self-assembly of molecular necklaces.
2002-03-13
Three different bonding modes of cyano groups in the coordination polymer [Cu(en)2(H(2)O)][Cu(en)(2)Ni(2)Cu(2)(CN)(10)] x 2H(2)O (en is 1,2-diaminoethane).
2002-03
Development of preparation methods for and insights obtained from atomic force microscopy of fluid spaces in cortical bone.
2002-02-28
Structure-directing coordination template effect of ethylenediamine in formations of ZnS and ZnSe nanocrystallites via solvothermal route.
2002-02-25
c-erbB-2 is not a major factor in the development of colorectal cancer.
2002-02-12
Schiff bis bases: analytical reagents. II. Spectrophotometric determination of manganese from pharmaceutical forms.
2002-02-01
[Occupational asthma due to amines].
2002-02
Experimental studies on the nature of bonding of DNA*bipyridyl-(ethylenediamine)platinum(II) and DNA*netropsin complexes in solution and oriented wet-spun films.
2002-02
Bis(ethylenediamine)copper(II) bis(O,O'-diethyl dithiophosphate).
2002-02
Molecular characteristics of glnA linked mutations in the nitrogen-fixing cyanobacterium Nostoc muscorum.
2002-02
Direct synthesis of peptides on convective interaction media monolithic columns for affinity chromatography.
2002-01-16
Syntheses, crystal structures, and density functional theory calculations of the closo-[1-M(CO)(3)(eta(4)-E(9))](4-) (E = Sn, Pb; M = Mo, W) cluster anions and solution NMR spectroscopic characterization of [1-M(CO)(3)(eta(4)-Sn(9))](4-) (M = Cr, Mo, W).
2002-01-14
Modulation of the release of endogenous gamma-aminobutyric acid by cannabinoids in the guinea pig ileum.
2002-01-02
Gramicidin derivatives as membrane-based pH sensors.
2002-01-02
Nitriles form mixed-coligand complexes with (99m)Tc-HYNIC-peptide.
2002-01
Optimization of urease immobilization onto non-porous HEMA incorporated poly(EGDMA) microbeads and estimation of kinetic parameters.
2002-01
Galactosylated alginate as a scaffold for hepatocytes entrapment.
2002-01
Secretion of a trypsin-like thiol protease by a new keratinolytic strain of Bacillus licheniformis.
2001-12-18
Enzymatic properties of sialic acid binding lectin from Rana catesbeiana modified with a water-soluble carbodiimide in the presence of various nucleophiles.
2001-12
Plane-wave density functional theoretic study of formation of clay-polymer nanocomposite materials by self-catalyzed in situ intercalative polymerization.
2001-11-28
[[Cu(en)(2)](2)Re(4)Te(4)(CN)(12)].5H(2)O and [[Cu(en)(2)](2)Re(6)Te(8)(CN)(6)].5H(2)O: bonding of a transition-metal complex to a rhenium chalcocyanide cluster.
2001-11-19
Gold-gold interactions as crystal engineering design elements in heterobimetallic coordination polymers.
2001-11-05
A three-dimensional porous framework complex, poly[[bis(ethylenediamine)copper(II)] [potassium hexacyanocobalt(III)]].
2001-11
Layered cobalt hydroxysulfates with both rigid and flexible organic pillars: synthesis, structure, porosity, and cooperative magnetism.
2001-10-31
Inhibition of cancer cell growth by ruthenium(II) arene complexes.
2001-10-25
The effect of pH and concentration upon aggregation transitions in aqueous solutions of poloxamine T701.
2001-10-23
[Effect of alpha-lipoic acid preparations on bilirubin and transferrin levels and ferritin iron and transferrin iron content].
2001-10-20
Synthesis and antifungal activity of 3,3'-ethylenebis(5-alkyl-1,3,5-thiadiazine-2-thiones).
2001-10
Polar nitrogen compounds and their behaviour in the drinking water treatment process.
2001-10
Predictive value of chromatin decondensation in vitro on fertilization rate after intracytoplasmic sperm injection (ICSI).
2001-10
Syntheses, vibrational spectra, and theoretical studies of the adamantanoid Sn(4)Ch(10)(4-) (Ch = Se, Te) anions: X-ray crystal structures of [18-crown-6-K](4)[Sn4Se10]*5en and [18-crown-6-K](4)[Sn4Te10]*3en*2THF.
2001-09-10
Design of oxytocin antagonists, which are more selective than atosiban.
2001-09
Effect of modification of the carboxyl groups of the sialic acid binding lectin from bullfrog (Rana catesbeiana) oocyte on anti-tumor activity.
2001-09
Aminoethylethanolamine: a new allergen in cosmetics?
2001-09
Synthesis and structure of [K(+)-(2,2)diaza-[18]-crown-6][K3Ge9]-2ethylenediamine: stabilization of the two-dimensional layer (2)(infinity)[K3Ge9(1-)].
2001-08-27
Prenatal HLA typing of uncultured amniocytes prior to the collection of related allogeneic cord blood.
2001-08
Speciation of rare earth elements in soil by sequential extraction then HPLC coupled with visible and ICP-MS detection.
2001-08
Hydrogen-bonded adducts of ferrocene-1,1'-diylbis(diphenylmethanol): monomeric and dimeric 1:1 adducts with 1,2-bis(4-pyridyl)ethane and 1,2-diaminoethane.
2001-08
[H3N(CH2)2NH3]0.5[BePO4], a beryllophosphate analogue of aluminosilicate zeolite gismondine.
2001-08
[Effect of calcium ion level in blood on physiological functions in rat subjected to immersion hypothermia].
2001-07
Rabbit M cells and dome enterocytes are distinct cell lineages.
2001-06
Use of a new HemoCue system for measuring haemoglobin at low concentrations.
2001-04
Mixed cobalt(III) complexes with aromatic amino acids and diamine. Part II. Synthesis and configuration of (1,2-diaminoethane)bis(L-tyrosinato)cobalt(III)complex diastereomers. The crystal structure of the delta-C1-cis(O) diastereomer.
2001
Utilization of quinolone drugs as monomers: characterization of the synthesis reaction products for poly(norfloxacin diisocyanatododecane polycaprolactone).
2001
Yield and post-yield behavior of mussel byssal thread: a self-healing biomolecular material.
2001
Kinetics and mechanisms of EDTA photocatalytic degradation with TiO2.
2001
[Effect of Na2H2EDTA on the viability of rats' organism during hypothermia].
2001
Non-detection of Chlamydia species in carotid atheroma using generic primers by nested PCR in a population with a high prevalence of Chlamydia pneumoniae antibody.
2001
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:49:43 GMT 2025
Edited
by admin
on Mon Mar 31 17:49:43 GMT 2025
Record UNII
91WQV43244
Record Status Validated (UNII)
Record Version
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Name Type Language
ETHYLENEDIAMINE DIHYDROCHLORIDE
II   MI   WHO-DD  
Systematic Name English
NSC-163962
Preferred Name English
Ethylenediamine dihydrochloride [WHO-DD]
Common Name English
1,2-ETHANEDIAMINE DIHYDROCHLORIDE
Systematic Name English
ETHYLENEDIAMINE DIHYDROCHLORIDE [II]
Common Name English
ETHYLENEDIAMINE DICHLORIDE
Systematic Name English
1,2-DIAMINOETHANE DIHYDROCHLORIDE
Systematic Name English
ETHYLENEDIAMINE DIHYDROCHLORIDE [MI]
Common Name English
Code System Code Type Description
FDA UNII
91WQV43244
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY
MERCK INDEX
m5119
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY Merck Index
MESH
C031234
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY
PUBCHEM
9521
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY
NCI_THESAURUS
C80927
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY
CHEBI
53626
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY
ECHA (EC/EINECS)
206-369-6
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
CONCEPT Industrial Aid
SMS_ID
100000115537
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY
EPA CompTox
DTXSID5043920
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY
NSC
163962
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY
CAS
333-18-6
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY
EVMPD
SUB30808
Created by admin on Mon Mar 31 17:49:43 GMT 2025 , Edited by admin on Mon Mar 31 17:49:43 GMT 2025
PRIMARY
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