ZOMETAPINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H15ClN4
Molecular Weight	274.749
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1N=C(C)C2=C1NCCN=C2C3=CC=CC(Cl)=C3

InChI

InChIKey=YCWROMXNZZIJDQ-UHFFFAOYSA-N

InChI=1S/C14H15ClN4/c1-9-12-13(10-4-3-5-11(15)8-10)16-6-7-17-14(12)19(2)18-9/h3-5,8,17H,6-7H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C14H15ClN4
Molecular Weight	274.749
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6542226 | https://www.researchgate.net/publication/285568859_An_early_phase_II_study_of_zometapine_a_new_antidepressant

Zometapine was developed as an antidepressant drug. This drug participated in phase II clinical trial in patients with depression where it showed as an effective agent. However, information about the further development of Zometapine is not available.

Approval Year

PubMed

Title	Date	PubMed
Effects of zometapine, a structurally novel antidepressant, in an animal model of depression.	1984-10	6542226

Sample Use Guides

In Vivo Use Guide

patients were administered zometapine in dosages of 300 to 600 mg/day for four weeks

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:52:07 GMT 2025` Edited by `admin` on `Mon Mar 31 17:52:07 GMT 2025`
Record UNII	9171J97IQP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CI-781

Preferred Name

English

ZOMETAPINE

Official Name

English

ZOMETAPINE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265