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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H19NO4
Molecular Weight 313.3478
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Hydroxycodeinone

SMILES

COC1=CC=C2C[C@H]3N(C)CC[C@@]45[C@@H](OC1=C24)C(=O)C=C[C@@]35O

InChI

InChIKey=YYCRAERBSFHMPL-XFKAJCMBSA-N
InChI=1S/C18H19NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-6,13,16,21H,7-9H2,1-2H3/t13-,16+,17+,18-/m1/s1

HIDE SMILES / InChI
Molecular Formula C18H19NO4
Molecular Weight 313.3478
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
149124
Targets

Targets

Primary TargetPharmacologyConditionPotency
DNA
282
Target ID: CHEMBL2311221
Crosslinking Agent
83
PubMed

PubMed

TitleDatePubMed
Modified in vivo comet assay detects the genotoxic potential of 14-hydroxycodeinone, an α,β-unsaturated ketone in oxycodone.
2015-12
THE RELATIONSHIP BETWEEN ANALGESIC ACTIVITY, ACUTE TOXICITY AND CHEMICAL STRUCTURE INESTERS OF 14-HYDROXYCODEINONE.
1964-12
Patents

Patents

20060014771
1
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:29:56 GMT 2025
Edited
by admin
on Mon Mar 31 19:29:56 GMT 2025
Record UNII
91138F771G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Hydroxycodeinone
MI  
Common Name English
OXYCODONE RELATED COMPOUND A
USP  
Preferred Name English
CODEINONE, 14-HYDROXY-
Common Name English
OXYCODONE HYDROCHLORIDE IMPURITY D [EP IMPURITY]
Common Name English
14-HYDROXYCODEINONE
Common Name English
OXYCODONE RELATED COMPOUND A [USP-RS]
Common Name English
14.BETA.-HYDROXYCODEINONE
Common Name English
CODEINE MONOHYDRATE IMPURITY K [EP IMPURITY]
Common Name English
OXYCODONE RELATED COMPOUND A CII
USP-RS  
Common Name English
(5.ALPHA.)-7,8-DIDEHYDRO-4,5-EPOXY-14-HYDROXY-3-METHOXY-17-METHYLMORPHINAN-6-ONE
Systematic Name English
HYDROXYCODEINONE [MI]
Common Name English
MORPHINAN-6-ONE, 7,8-DIDEHYDRO-4,5-EPOXY-14-HYDROXY-3-METHOXY-17-METHYL-, (5-.ALPHA.)-
Common Name English
OXYCODONE RELATED COMPOUND A [USP IMPURITY]
Common Name English
CODEINE HYDROCHLORIDE DIHYDRATE IMPURITY K [EP IMPURITY]
Common Name English
CODEINE PHOSPHATE HEMIHYDRATE IMPURITY K [EP IMPURITY]
Common Name English
Code System Code Type Description
CAS
508-54-3
Created by admin on Mon Mar 31 19:29:56 GMT 2025 , Edited by admin on Mon Mar 31 19:29:56 GMT 2025
PRIMARY
MERCK INDEX
m6132
Created by admin on Mon Mar 31 19:29:56 GMT 2025 , Edited by admin on Mon Mar 31 19:29:56 GMT 2025
PRIMARY Merck Index
RS_ITEM_NUM
1485216
Created by admin on Mon Mar 31 19:29:56 GMT 2025 , Edited by admin on Mon Mar 31 19:29:56 GMT 2025
PRIMARY
EPA CompTox
DTXSID801316557
Created by admin on Mon Mar 31 19:29:56 GMT 2025 , Edited by admin on Mon Mar 31 19:29:56 GMT 2025
PRIMARY
FDA UNII
91138F771G
Created by admin on Mon Mar 31 19:29:56 GMT 2025 , Edited by admin on Mon Mar 31 19:29:56 GMT 2025
PRIMARY
ECHA (EC/EINECS)
208-085-8
Created by admin on Mon Mar 31 19:29:56 GMT 2025 , Edited by admin on Mon Mar 31 19:29:56 GMT 2025
PRIMARY
MESH
C008000
Created by admin on Mon Mar 31 19:29:56 GMT 2025 , Edited by admin on Mon Mar 31 19:29:56 GMT 2025
PRIMARY
PUBCHEM
9926820
Created by admin on Mon Mar 31 19:29:56 GMT 2025 , Edited by admin on Mon Mar 31 19:29:56 GMT 2025
PRIMARY
Related Record Type Details
Structure of CODEINE PHOSPHATE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of CODEINE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of CODEINE HYDROCHLORIDE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of OXYCODONE HYDROCHLORIDE
PARENT -> IMPURITY
Related Record Type Details
Structure of Hydroxycodeinone
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