TAGRAXOFUSP

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 07:04:13 GMT 2025` Edited by `admin` on `Wed Apr 02 07:04:13 GMT 2025`
Protein Type	TOXIN
Protein Sub Type	TOXIN CONJUGATE
Sequence Type	COMPLETE
Record UNII	8ZHS5657EH
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

SL-401

Preferred Name

English

TAGRAXOFUSP

Official Name

English

MOLECULE 129

Code

English

DIPHTHERIA TOXIN (CORYNEBACTERIUM DIPHTHERIAE CATALYTIC DOMAIN/TRANSMEMBRANE DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID LINKER) FUSION PROTEIN WITH INTERLEUKIN 3 (HUMAN)

Systematic Name

English

DT-3881L3

Code

English

tagraxofusp [INN]

Common Name

English

MOLECULE-129

Code

English

L-METHIONYLDIPHTHERIA TOXIN-(1-386)-PEPTIDE (1-387) FUSION PROTEIN WITH L-ARGINYL-L-PROLYL-L-HISTIDYL-L-METHIONYL-(8-L-SERINE(P>S399))INTERLEUKIN-3 (HOMO SAPIENS) (388-524), NON-GLYCOSYLATED.

Systematic Name

English

DIPHTHERIA TOXIN-IL-3 FUSION PROTEIN TARGETING IL-3 RECEPTOR

Common Name

English

TAGRAXOFUSP [USAN]

Common Name

English

TAGRAXOFUSP [MI]

Common Name

English

Tagraxofusp [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

332811

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

FDA ORPHAN DRUG

397413

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

Code System Code Type Description

CAS

1810027-09-8

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

NO STRUCTURE GIVEN

USAN

FG-05

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

FDA UNII

8ZHS5657EH

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

WIKIPEDIA

Tagraxofusp

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

NCI_THESAURUS

C64769

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

RXCUI

2109054

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

ALTERNATIVE

INN

10770

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

SMS_ID

100000178398

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

DRUG CENTRAL

5323

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

CAS

2055491-00-2

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

DAILYMED

8ZHS5657EH

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

MERCK INDEX

m12148

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

DRUG BANK

DB14731

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

RXCUI

2109055

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

LACTMED

Tagraxofusp

Created by admin on Wed Apr 02 07:04:13 GMT 2025 , Edited by admin on Wed Apr 02 07:04:13 GMT 2025

PRIMARY

From	To
1_187	1_202
1_407	1_475

Related Record Type Details

TAGRAXOFUSP-ERZS

INNOVATOR->PARENT

Amount:


					3JW47OGM6P

INTERLEUKIN-3 RECEPTOR SUBUNIT ALPHA

TARGET->CONJUGATED TOXIN

Amount:

TAGRAXOFUSP-ERZS

SUB_CONCEPT->SUBSTANCE

Amount:

Related Record Type Details


					8ZHS5657EH

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL