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Details

Stereochemistry ABSOLUTE
Molecular Formula C26H37N3O3
Molecular Weight 439.5913
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MN-25

SMILES

CC1(C)[C@]2([H])CC[C@@](C)(C2)[C@]1([H])N=C(c3cn(CCN4CCOCC4)c5c3cccc5OC)O

InChI

InChIKey=VQGDMQICNRCQEH-UFKXBGGNSA-N
InChI=1S/C26H37N3O3/c1-25(2)18-8-9-26(3,16-18)24(25)27-23(30)20-17-29(11-10-28-12-14-32-15-13-28)22-19(20)6-5-7-21(22)31-4/h5-7,17-18,24H,8-16H2,1-4H3,(H,27,30)/t18-,24-,26+/m1/s1

HIDE SMILES / InChI

Molecular Formula C26H37N3O3
Molecular Weight 439.5913
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: P34972
Gene ID: 1269.0
Gene Symbol: CNR2
Target Organism: Homo sapiens (Human)
11.0 nM [Ki]
Target ID: P21554|||Q5UB37
Gene ID: 1268.0
Gene Symbol: CNR1
Target Organism: Homo sapiens (Human)
245.0 nM [Ki]
Substance Class Chemical
Created
by admin
on Fri Jun 25 20:32:49 UTC 2021
Edited
by admin
on Fri Jun 25 20:32:49 UTC 2021
Record UNII
8WXU5YRE25
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MN-25
Common Name English
N-(S)-FENCHYL-1-(2-MORPHOLINOETHYL)-7-METHOXYINDOLE-3-CARBOXAMIDE
Systematic Name English
UR-12
Code English
7-METHOXY-1-(2-MORPHOLINOETHYL)-N-((1S,4R)-1,3,3-TRIMETHYLBICYCLO(2.2.1)HEPTAN-2-YL)-1H-INDOLE-3-CARBOXAMIDE
Systematic Name English
Code System Code Type Description
CAS
354569-21-4
Created by admin on Fri Jun 25 20:32:49 UTC 2021 , Edited by admin on Fri Jun 25 20:32:49 UTC 2021
NON-SPECIFIC STEREOCHEMISTRY
PUBCHEM
71308243
Created by admin on Fri Jun 25 20:32:49 UTC 2021 , Edited by admin on Fri Jun 25 20:32:49 UTC 2021
PRIMARY
FDA UNII
8WXU5YRE25
Created by admin on Fri Jun 25 20:32:49 UTC 2021 , Edited by admin on Fri Jun 25 20:32:49 UTC 2021
PRIMARY
CAS
501926-82-5
Created by admin on Fri Jun 25 20:32:49 UTC 2021 , Edited by admin on Fri Jun 25 20:32:49 UTC 2021
PRIMARY
WIKIPEDIA
MN-25
Created by admin on Fri Jun 25 20:32:49 UTC 2021 , Edited by admin on Fri Jun 25 20:32:49 UTC 2021
PRIMARY
Related Record Type Details
TARGET -> AGONIST
MN-25 (UR-12) acts as a reasonably selective agonist of peripheral cannabinoid receptors. It has moderate affinity for CB2 receptors with a Ki of 11 nM.
Ki
Related Record Type Details
ACTIVE MOIETY