IPROZILAMINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H22ClN5S
Molecular Weight	315.865
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of IPROZILAMINE

Structure Search

SMILES

CSC1=C(Cl)N=C(NC(C)C)N=C1N2CCN(C)CC2

InChI

InChIKey=UMMYPDFDLDVDCZ-UHFFFAOYSA-N

InChI=1S/C13H22ClN5S/c1-9(2)15-13-16-11(14)10(20-4)12(17-13)19-7-5-18(3)6-8-19/h9H,5-8H2,1-4H3,(H,15,16,17)

HIDE SMILES / InChI

Molecular Formula	C13H22ClN5S
Molecular Weight	315.865
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1151967

IPROZILAMINE, a member of 4-piperazinopyrimidines, has powerful antiemetic activity. It also exhibits a relaxant effect on smooth muscle fiber.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Synthesis and pharmacological properties of 4-piperazino-5-methylthiopyrimidines. Selection of new antiemetic agents.	1975-06	1151967

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:42:18 GMT 2025` Edited by `admin` on `Wed Apr 02 09:42:18 GMT 2025`
Record UNII	8WTG4RSP9Y
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IPROZILAMINE

Official Name

English

iprozilamine [INN]

Preferred Name

English

4-CHLORO-2-(ISOPROPYLAMINO)-6-(4-METHYL-1-PIPERAZINYL)-5-(METHYLTHIO)PYRIMIDINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C267

Created by admin on Wed Apr 02 09:42:18 GMT 2025 , Edited by admin on Wed Apr 02 09:42:18 GMT 2025

Code System Code Type Description

FDA UNII

8WTG4RSP9Y

Created by admin on Wed Apr 02 09:42:18 GMT 2025 , Edited by admin on Wed Apr 02 09:42:18 GMT 2025

PRIMARY

ChEMBL

CHEMBL34246

Created by admin on Wed Apr 02 09:42:18 GMT 2025 , Edited by admin on Wed Apr 02 09:42:18 GMT 2025

PRIMARY

NCI_THESAURUS

C65958

Created by admin on Wed Apr 02 09:42:18 GMT 2025 , Edited by admin on Wed Apr 02 09:42:18 GMT 2025

PRIMARY

PUBCHEM

68725

Created by admin on Wed Apr 02 09:42:18 GMT 2025 , Edited by admin on Wed Apr 02 09:42:18 GMT 2025

PRIMARY

EPA CompTox

DTXSID60204042

Created by admin on Wed Apr 02 09:42:18 GMT 2025 , Edited by admin on Wed Apr 02 09:42:18 GMT 2025

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EVMPD

SUB08288MIG

Created by admin on Wed Apr 02 09:42:18 GMT 2025 , Edited by admin on Wed Apr 02 09:42:18 GMT 2025

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INN

3945

Created by admin on Wed Apr 02 09:42:18 GMT 2025 , Edited by admin on Wed Apr 02 09:42:18 GMT 2025

PRIMARY

SMS_ID

100000083147

Created by admin on Wed Apr 02 09:42:18 GMT 2025 , Edited by admin on Wed Apr 02 09:42:18 GMT 2025

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CAS

55477-19-5

Created by admin on Wed Apr 02 09:42:18 GMT 2025 , Edited by admin on Wed Apr 02 09:42:18 GMT 2025

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