ZENAZOCINE MESYLATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C23H35NO2.CH4O3S
Molecular Weight	453.635
Optical Activity	( + / - )
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CS(O)(=O)=O.CC(C)CCC(=O)CC[C@]1(C)[C@H]2CC3=CC=C(O)C=C3[C@]1(C)CCN2C

InChI

InChIKey=GLJVRAXBUACXBP-HZLAGBECSA-N

InChI=1S/C23H35NO2.CH4O3S/c1-16(2)6-8-18(25)10-11-23(4)21-14-17-7-9-19(26)15-20(17)22(23,3)12-13-24(21)5;1-5(2,3)4/h7,9,15-16,21,26H,6,8,10-14H2,1-5H3;1H3,(H,2,3,4)/t21-,22+,23-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C23H35NO2
Molecular Weight	357.5295
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	CH4O3S
Molecular Weight	96.106
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2860595 | https://doi.org/10.1016/S0065-7743(08)61029-5

Zenazocine is an opioid analgesic that mixes both agonist/antagonist activities. This compound participated in phase II clinical trial, however, the further development was ultimately halted and it has never been marketed.

Approval Year

PubMed

Title	Date	PubMed
Pharmacological profiles of tonazocine (Win 42156) and zenazocine (Win 42964).	1985 Feb	2860595

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:07:15 UTC 2023` Edited by `admin` on `Fri Dec 15 15:07:15 UTC 2023`
Record UNII	8WIL6L9U01
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ZENAZOCINE MESYLATE

Official Name

English

ZENAZOCINE MESILATE

Common Name

English

(±)-1-((2R*,6S*,11S*)-1,2,3,4,5,6-HEXAHYDRO-8-HYDROXY-3,6,11-TRIMETHYL-2,6-METHANO-3-BENZAZOCIN-11-YL)-6-METHYL-3-HEPTANONE METHANESULPHONATE (SALT)

Common Name

English

3-HEPTANONE, 1-(1,2,3,4,5,6-HEXAHYDRO-8-HYDROXY-3,6,11-TRIMETHYL-2,6-METHANO-3-BENZAZOCIN-11-YL)-6-METHYL-, (2.ALPHA.,6.ALPHA.,11S*)-(±)-, METHANESULPHONATE (SALT)

Common Name

English

3-HEPTANONE, 1-(1,2,3,4,5,6-HEXAHYDRO-8-HYDROXY-3,6,11-TRIMETHYL-2,6-METHANO-3-BENZAZOCIN-11-YL)-6-METHYL-, (2.ALPHA.,6.ALPHA.,11S*)-(±)-, METHANESULFONATE (SALT)

Common Name

English

WIN 42964-4

Code

English

WIN-429644

Code

English

MCV-4176

Code

English

WIN-42964-4

Code

English

ZENAZOCINE MESYLATE [USAN]

Common Name

English

3-HEPTANONE, 1-((2R,6S,11S)-1,2,3,4,5,6-HEXAHYDRO-8-HYDROXY-3,6,11-TRIMETHYL-2,6-METHANO-3-BENZAZOCIN-11-YL)-6-METHYL-, REL-, METHANESULFONATE (1:1)

Systematic Name

English

(±)-1-((2R*,6S*,11S*)-1,2,3,4,5,6-HEXAHYDRO-8-HYDROXY-3,6,11-TRIMETHYL-2,6-METHANO-3-BENZAZOCIN-11-YL)-6-METHYL-3-HEPTANONE METHANESULFONATE (SALT)

Common Name

English

NIH-9625

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C681